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Frontiers of Agriculture in China

ISSN 1673-7334

ISSN 1673-744X(Online)

CN 11-5729/S

Front Agric Chin    2009, Vol. 3 Issue (1) : 47-54     DOI: 10.1007/s11703-009-0001-6
Transcriptional responses and regulations to deficient phosphorus in plants
Jinxiang BAO1, Shuhua ZHANG2, Wenjing LU2, Chengjin GUO1, Juntao GU2, Kai XIAO1()
1. College of Agronomy, Agricultural University of Hebei, Baoding 071001, China; 2. College of Life Sciences, Agricultural University of Hebei, Baoding 071001, China
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Significant progress has been made over the past several years in the understanding of phosphorus (Pi)-starvation responses in plants and their regulation. The transcriptional changes that occur in response to Pi starvation are beginning to be revealed, although much is left to understand about their significance. In this paper, the recent progresses on the gene expression changes under deficient-Pi, cis-regulatory elements involved in response to deficient-Pi, the transcriptional control of Pi-starvation responses in eukaryotes, transcription factors involved in response to Pi-starvation, the role of MicroRNA on regulation of phosphate homeostasis, and phosphate sensing and signal transduction in plants have been summarized. The purpose of this review is to provide some basis for further elucidation of the transcriptional responses and regulations, and the networks of Pi sensing and signal transduction under deficient-Pi in plants in the future.

Keywords deficient phosphorus      transcriptional response      transcriptional factor      Pi sensing and signal transduction     
Corresponding Authors: XIAO Kai,   
Issue Date: 05 March 2009
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1 Abel S, Ticconi C A, Delatorre C A (2002). Phosphate sensing in higher plants. Physiologia Plantarum , 115: 1–8
2 Adai A, Johnson C, Mlotshwa S, Archer-Evans S, Manocha V, Vance V, Sundaresan V (2005). Computational prediction of miRNAs in Arabidopsis thaliana. Genome Research , 15: 78–91
3 Aoyama T, Dong C H, Wu Y, Carabelli M, Sessa G, Ruberti U, Morelli G, Chua N H (1995). Ectopic expression of the Arabidopsis transcriptional activator Athb-1 alters leaf cell fate in tobacco. The Plant Cell , 7: 1773–1785
4 Atchley W R, Therhalle W, Dress A (1999). Positional dependence, cliques and predictive motifs in the bHLH protein domain. Journal of Molecular Evolution , 48: 501–516
5 Aung K, Lin S I, Wu C C, Huang Y T, Su C, Chiou T J (2006). pho2, a phosphate overaccumulator, is caused by a nonsense mutation in a microRNA399 target gene. Plant Physiology , 141: 1000–1011
6 Axtell M J, Bartel D P (2005). Antiquity of microRNAs and their targets in land plants. The Plant Cell , 17: 1658–1673
7 Baldwin J C, Karthikeyan A S, Raghothama K G (2001). Leps2, a phosphorus starvation-induced novel acid phosphatase from tomato. Plant Physiology , 125: 728–737
8 Bartel D P (2004). MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell , 116: 218–297
9 Bates T R, Lynch J P (1996). Stimulation of root hair elongation in Arabidopsis thaliana by low phosphorous availability. Plant, Cell and Environment , 19: 529–538
10 Burleigh S H, Harrison M J (1998). Characterization of the Mt4 gene from Medicago truncatula. Gene , 216: 47–53
11 Burleigh S H, Harrison M J (1999). The down regulation of Mt4-like genes by phosphate fertilization occurs systemically and involves phosphate translocation to the shoots. Plant Physiology , 119: 241–248
12 Burleigh S H, Cavagnaro T, Jakobsen I (2002). Functional diversity of arbuscular mycorrhizas extends to the expression of plant genes involved in P nutrition. Journal of Experimental Botany , 53: 1593–1601
13 Carrington J C, Ambros V (2003). Role of microRNAs in plant and animal development. Science , 301: 336–338
14 Chiou T J, Aung K, Lin S I, Wu C C, Chiang S F, Su C (2005). Regulation of phosphate homeostasis by microRNA in Arabidopsis. The Plant Cell , 18: 412–421
15 Creelman R A, Mullet J E (1997). Biosynthesis and action of jasmonates in plants. Annual Review Plant Physiology Plant Molecular Biology , 48: 355–381
16 Delhaize E, Randall P J (1995). Characterization of a phosphate-accumulator mutant of Arabidopsis thaliana. Plant Physiology , 107: 207–213
17 Devaiah B N, Karthikeyan A S, Raghothama K G (2007b). WRKY75 transcription factor is a modulator of phosphate acquisition and root development in Arabidopsis. Plant Physiology , 143: 1789–1801
18 Devaiah B N, Nagarajan V K, Raghothama K G (2007a). Phosphate homeostasis and root development in Arabidopsis are synchronized by the zinc finger transcription factor ZAT6. Plant Physiology , 145: 147–159
19 DeWald D B, Sadka A, Mullet J E (1994). Sucrose modulation of soybean Vsp gene expression is inhibited by auxin. Plant Physiology , 104: 439–444
20 Dugas D V, Bartel B (2004). MicroRNA regulation of gene expression in plants. Current Opinion Plant Biology , 7: 512–520
21 Englbrecht C C, Schoof H, B?hm S (2004). Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. BMC Genomics , 5: 39–46
22 Fujii H, Chiou T J, Lin S I, Aung K, Zhu J K (2005). A miRNA involved in phosphate-starvation response in Arabidopsis. Current Biology , 15: 2038–2043
23 Hammond J P, Bennett M J, Bowen H C, Broadley M R, Eastwood D C, May S T, Rahn C, Swarup R, Woolaway K E, White P J (2003). Changes in genes expression in Arabidopsis shoots during phosphate starvation and the potential for developing smart plants. Plant Physiology , 132: 1–19
24 Harrison M J (1999). Molecular and cellular aspects of the arbuscular mycorrhizal symbiosis. Annual Reviews in Plant Physiology and Plant Molecular Biology , 50: 361–389
25 Holford I C R (1997) Soil phosphorus: its measurement, and its uptake by plants. Australia Journal of Soil Research , 35: 227–239
26 Kaffman A, Rank N M, O’Neill E M, Huang L S, O’Shea E K (1998a). The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature , 396: 482–486
27 Kaffman A, Rank N M, O’Shea E K (1998b). Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes and Development , 12: 2673–2683
28 Kidner C A, Martienssen R A (2005). The developmental role of microRNA in plants. Current Opinion Plant Biology , 8: 38–44
29 K?ck M, Theierl K, Stenzel I, Glund K (1998). Extracellular administration of phosphate-sequestering metabolites induces ribonucleases in cultured tomato cells. Planta , 204: 404–407
30 Lenburg M E, O’Shea E K (1996). Signaling phosphate starvation. Trends in Biochemical Sciences , 21: 383–387
31 Linkohr B I, Williamson L C, Fitter A H, Leyser H M (2002). Nitrate and phosphate availability and distribution have different effects on root system architecture of Arabidopsis. The Plant Journal , 29: 751–760
32 Liu C, Muchhal U S, Raghothama K G (1997). Differential expression of TPSI1, a phosphate starvation-induced gene in tomato. Plant Molecular Biology , 33: 867–874
33 López-Bucio J, Hernández-Abreu E, Sánchez-Calderón L, Nieto-Jacobo M F, Simpson J, Herrera-Estrella L (2002). Phosphate availability alters architecture and causes changes in hormone sensitivity in the Arabidopsis root system. Plant Physiology , 129: 244–256
34 Ma Z, Bielenberg D, Brown K M, Lynch J P (2001). Regulation of root hair density by phosphorus availability in Arabidopsis thaliana. Plant, Cell and Environment , 24: 459–467
35 Martín A C, del Pozo J C, Iglesias J, Rubio V, Solano R, de la Pe?a A, Leyva A, Paz-Ares J (2000). Influence of cytokinins on the expression of phosphate starvation responsive genes in Arabidopsis. The Plant Journal , 24: 559–567
36 Mason H S, DeWald D B, Creelman R A, Mullet J E (1992). Coregulation of soybean vegetative storage protein gene expression by methyl jasmonate and soluble sugars. Plant Physiology , 98: 859–867
37 Mason H S, Mullet J E (1990). Expression of two soybean vegetative storage protein genes during development and in response to water deficit, wounding, and jasmonic acid. The Plant Cell , 2: 569–579
38 Massari M E, Murre C (2000). Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Molecular Cell Biology , 20: 429–440
39 Meijer A, Scarpella E, Van Dijk E L, Qin L, Taal J C, Rueb S, Harrington S E, McCouch S R, Schilperoort R, Hoge J H C (1997). Transcriptional repression by Oshox1, a novel homeodomain leucine zipper protein from rice. Plant Journal , 11: 263–276
40 Mukatira U T, Liu C, Varadarajan D K, Raghothama K G (2001). Negative regulation of phosphate starvation-induced genes. Plant Physiology , 127: 1854–1862
41 Ohta M, Matsui K, Hiratsu K, Shinshi H, Ohme-Takagi M (2001). Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. The Plant Cell , 13: 1959–1968
42 Oshima Y (1997). The phosphatase system in Saccharomyces cerevisiae. Genes Genetics System , 72: 323–334
43 Poirier Y, Thoma S, Somerville C, Schiefelbein J (1991). A mutant of Arabidopsis deficient in xylem loading of phosphate. Plant Physiology , 97: 1087–1093
44 Raghothama K G (1999). Phosphate acquisition. Annual Review of Plant Physiology , 50: 665–693
45 Rausch C, Bucher M (2002). Molecular mechanisms of phosphate transport in plants. Planta , 216: 23–37
46 Reinhart B J, Weinstein E G, Rhoades M W, Bartel B, Bartel D P (2002). MicroRNAs in plants. Genes and Development , 16: 1616–1626
47 Rubio V, Linhares F, Solano R, Martín A C, Iglesias J, Leyva A, Paz-Ares J (2001). A conserved MYB transcription factor involved in phosphate starvation signalling both in vascular plants and unicellular algae. Genes and Development , 15: 2122–2133
48 Runge-Metzger A (1995). Closing the cycle: obstacles to efficient P management for improved global security. In: Tiessen H, ed. Phosphorus in the global environment: transfers, cycles and management . New York: John Wiley & Sons, 27–42
49 Sessa G, Carabelli M, Ruberti I (1994). Identification of distinct families of HD-ZIP proteins in Arabidopsis thaliana. In: Coruzzi G, Puigdomenech P, eds. Plant Molecular Biology, NATO ASI Series , Vol. H81. Berlin: Springer-Verlag, 411–426
50 Sessa G, Morelli G, Ruberti I (1993). The Athb-1 and-2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities. EMBO Journal , 12: 3507–3517
51 Sessa G, Steindler C, Morelli G, Ruberti I (1998). The Arabidopsis Athb-8, -9, and -14 genes are members of a small gene family coding for highly related HD-ZIP proteins. Plant Molecular Biology , 38: 609–622
52 Soderman E, Mattsson J, Engstrom P (1996). The Arabidopsis homeobox gene athb-7 is induced by water-deficit and by abscisic acid. Planta , 10: 275–281
53 Staswick P E (1990). Novel regulation of vegetative storage protein genes. The Plant Cell , 2: 1–6
54 Steindler C, Matteucci A, Sessa G, Weimar T, Ohgishi M, Aoyama T, Morelli G, Ruberti I (1999). Shade avoidance responses are mediated by the ATHB-2 HD-Zip protein, a negative regulator of gene expression. Development , 126: 4235–4245
55 Sunkar R, Girke T, Jain P K, Zhu J K (2005). Cloning and characterization of microRNAs from rice. The Plant Cell , 17: 1397–1411
56 Tang Z, Sadka A, Morishige D T, Mullet J E (2001). Homeodomain leucine zipper proteins bind to the phosphate response domain of the soybean VspB tripartite promoter. Plant Physiology , 125: 797–809
57 Ulker B, Somssich I E (2004). WRKY transcription factors: from DNA binding towards biological function. Current Opinion Plant Biology , 7: 491–498
58 Vance C P, Uhde-Stone C, Allan D L (2003). Phosphorus acquisition and use: critical adaptations by plants for securing a nonrenewable resource. New Phytologist , 157: 423–447
59 Von Uexküll H R, Mutert E (1995). Global extent, development and economic impact of acid soils. Plant and Soil , 171: 1–15
60 Wang Y H, Garvin D F, Kochian L V (2002). Rapid induction of regulatory and transporter genes in response to phosphorus, potassium, and iron deficiencies in tomato roots. Evidence for cross talk and root/rhizosphere-mediated signals. Plant Physiology , 130: 1361–1370
61 Wasaki J, Yonetani R, Shinano T, Kai M, Osaki M (2003). Expression of the OsPI1 gene, cloned from rice roots using cDNA microarray, rapidly responds to phosphorus status. New Phytologist , 158: 603–605
62 Watt M, Evans J R (1999). Proteoid roots. Physiology and development. Plant Physiology , 121: 317–324
63 Williamson L C, Ribrioux S P, Fitter A H, Leyser H M (2001). Phosphate availability regulates root system architecture in Arabidopsis. Plant Physiology , 126: 875–882
64 Wu P, Ma L, Hou X, Wang M, Wu Y, Liu F, Deng X W (2003). Phosphate starvation triggers distinct alterations of genome expression in Arabidopsis roots and leaves. Plant Physiology , 132: 1260–1271
65 Wykoff D D, Grossman A R, Weeks D P, Usuda H, Shimogawara K (1999). Psr1, a nuclear localized protein that regulates phosphorus metabolism in Chlamydomonas. Proceedings of the National Academy of Sciences , USA, 96: 15336–15341
66 Xiao K, Liu J, Dewbre G, Harrison M, Wang Z (2006). Isolation and characterization of root-specific phosphate transporter promoters from Medicago truncatula. Plant Biology , 8: 439–449
67 Yi K, Wu Z, Zhou J, Du L, Guo L, Wu Y, Wu P (2005). OsPTF1, a novel transcription factor involved in tolerance to phosphate starvation in rice. Plant Physiology , 138: 2087–2096
68 Zhou J, Jiao F, Wu Z, Li Y, Wang X, He X, Wu P (2008). OsPHR2 is involved in phosphate-starvation signaling and excessive phosphate accumulation in shoots of plants. Plant Physiology , 146: 1673–1686
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