|
Iron oxide nanoparticle-based theranostics for cancer imaging and therapy
Xiaoqing REN,Hongwei CHEN,Victor YANG,Duxin SUN
Front. Chem. Sci. Eng.. 2014, 8 (3): 253-264.
https://doi.org/10.1007/s11705-014-1425-y
Theranostic platform, which is equipped with both diagnostic and therapeutic functions, is a promising approach in cancer treatment. From various nanotheranostics studied, iron oxide nanoparticles have advantages since IONPs have good biocompatibility and spatial imaging capability. This review is focused on the IONP-based nanotheranostics for cancer imaging and treatment. The most recent progress for applications of IONP nanotheranostics is summarized, which includes IONP-based diagnosis, magnetic resonance imaging (MRI), multimodal imaging, chemotherapy, hyperthermal therapy, photodynamic therapy, and gene delivery. Future perspectives and challenges are also outlined for the potential development of IONP based theranostics in clinical use.
Figures and Tables |
References |
Related Articles |
Metrics
|
|
The influence of manufacturing parameters and adding support layer on the properties of Zirfon? separators
Li XU,Yue YU,Wei LI,Yan YOU,Wei XU,Shaoxing ZHANG
Front. Chem. Sci. Eng.. 2014, 8 (3): 295-305.
https://doi.org/10.1007/s11705-014-1433-y
The composite separator comprising of polysulfone and zirconia was prepared by phase inversion precipitation technique. The influence of manufacturing parameters on its properties was investigated, and the results show that the manufacturing parameters affect the ionic resistance and maximum pore size significantly. A modified composite separator with a support layer was prepared to enhance the tensile strength of separator. By adding support layer, the tensile strength of the separator increases from 1.85 MPa to 13.66 MPa. In order to evaluate the practical applicability of the composite separator, a small-scale industrial electrolytic experiment was conducted to investigate the changes of cell voltage, gas purity and separator stability. The results show that the modified composite separator has a smaller cell voltage and a higher H2 purity than the asbestos separator, and are promising material for industrial hydrogen production.
Figures and Tables |
References |
Related Articles |
Metrics
|
|
Calculation on phase diagrams of polyetherimide/ N,N-dimethylacetamide/H2O-BuOH casting system and their relevance to membrane performances
Ming TAN,Gaohong HE,Yan DAI,Rujie WANG,Wenhua SHI
Front. Chem. Sci. Eng.. 2014, 8 (3): 312-319.
https://doi.org/10.1007/s11705-014-1434-x
The ternary phase diagrams of polyetherimide (PEI)/N,N-dimethylacetamide (DMAc) with H2O and BuOH as non-solvent were simulated using solubility parameter and Flory-Huggins theory. The phase diagrams show that 5.5% H2O/BuOH system containing 5% BuOH and 0.5% H2O, or 6.5% H2O/BuOH system containing 6.2% BuOH and 0.3% H2O is required to induce liquid-liquid demixing for 20 wt-% PEI/DMAc casting solution. Therefore, BuOH can enhance the phase separation of the PEI casting solution and hereby induce higher porosity of the membrane, and the diffusion of BuOH into the water coagulation bath causes larger pore size easily compared with DMAc. Our predictions that the membrane pure water flux first increases then decreases, and the rejection ratio of bovine serum albumin decreases with the increasing concentration of BuOH were validated by the experiments using the prepared membranes.
Figures and Tables |
References |
Related Articles |
Metrics
|
|
Isolation, identification and primary application of bacteria from putrid alkaline silica sol
Lijie REN,Ye HAN,Shuwen YANG,Xiqian TAN,Jin WANG,Xin ZHAO,Jie FAN,Ting DONG,Zhijiang ZHOU
Front. Chem. Sci. Eng.. 2014, 8 (3): 330-339.
https://doi.org/10.1007/s11705-014-1419-9
The putrefaction of alkaline silica sol was investigated in this paper. The total colony numbers in three alkaline silica sol samples were 1.47×105, 1.25×104, and 9.45×104 cfu·mL–1, respectively. The salt- and alkali-tolerant strains were isolated and selected using nutrient agar medium at 2.5% salinity and pH 9.5. Basic morphological, physiological and biochemical tests were conducted to confirm the preliminary characterizations of the strains. Based on API 50 CH test and 16S rDNA gene sequence analysis, the isolated strains were finally identified as Exiguobacterium aurantiacum, Cyclobacteriaceae bacterium, Microbacterium sp., Acinetobacter sp., Stenotrophomonas maltophilia and Bacillus thuringiensis. The survivability of the strains under different conditions such as salinities, acidities and temperatures was also studied. Some suitable methods for degerming, such as product pipe steam sterilization and regular canister cleaning, were proposed. To explore the possibility of isolates in industrial application, their alkaline protease and amylase production abilities were preliminarily studied. Five strains produced alkaline protease, whereas two strains produced alkaline amylase. Thus, understanding of the putrefaction on alkaline silica sol would be beneficial for improving industrial production.
Figures and Tables |
References |
Related Articles |
Metrics
|
|
CuAlCl4 doped MIL-101 as a high capacity CO adsorbent with selectivity over N2
Yixiu WANG,Chao LI,Fanchao MENG,Shuling LV,Jintao GUO,Xiaoqin LIU,Chongqing WANG,Zhengfei MA
Front. Chem. Sci. Eng.. 2014, 8 (3): 340-345.
https://doi.org/10.1007/s11705-014-1438-6
A CuAlCl4 doped metal organic framework, CuAlCl4@MIL-101, was prepared by introducing CuAlCl4 into the pores of MIL-101 for the selective adsorption of CO over N2. The CuAlCl4 molecules were evenly distributed into various pores sizes and did not change the intrinsic structure of the MIL-101. Isotherms for CO and N2 adsorption at 298 K showed that the CO capacity on CuAlCl4@MIL-101 was much higher than that on virgin MIL-101, whereas the N2 capacity decreased. The selectivity for CO over N2 improved from 4.64 to 31.5 at 298 K and 1 bar. The CuAlCl4@MIL-101 adsorbent displayed outstanding CO adsorption stability and the adsorbent could be regenerated by applying a simple vacuum of 4 mmHg.
Figures and Tables |
References |
Related Articles |
Metrics
|
15 articles
|