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Determination of selected semi-volatile organic compounds in water using automated online solid-phase extraction with large-volume injection/gas chromatography/mass spectrometry |
Yongtao LI1(), Christina L. MCCARTY1, Ed J. GEORGE2 |
1. Drinking Water Quality Laboratory, Underwriters Laboratories Inc., South Bend, IN 46617, USA; 2. Chemical Analysis, Bruker Daltonics, Fremont, CA 94538, USA |
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Abstract A rapid, sensitive, and cost-effective analytical method was developed for the analysis of selected semi-volatile organic compounds in water. The method used an automated online solid-phase extraction technique coupled with programmed-temperature vaporization large-volume injection gas chromatography/mass spectrometry. The water samples were extracted by using a fully automated mobile rack system based on x-y-z robotic techniques using syringes and disposable 96-well extraction plates. The method was validated for the analysis of 30 semi-volatile analytes in drinking water, groundwater, and surface water. For a sample volume of 10 mL, the linear calibrations ranged from 0.01 or 0.05 to 2.5μg·L-1, and the method detection limits were less than 0.1μg·L-1. For the reagent water samples fortified at 1.0μg·L-1 and 2.0?μg·L-1, the obtained mean absolute recoveries were 70%–130% with relative standard deviations of less than 20% for most analytes. For the drinking water, groundwater, and surface water samples fortified at 1.0μg·L-1, the obtained mean absolute recoveries were 50%–130% with relative standard deviations of less than 20% for most analytes. The new method demonstrated three advantages: 1) no manipulation except the fortification of surrogate standards prior to extraction; 2) significant cost reduction associated with sample collection, shipping, storage, and preparation; and 3) reduced exposure to hazardous solvents and other chemicals. As a result, this new automated method can be used as an effective approach for screening and/or compliance monitoring of selected semi-volatile organic compounds in water.
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Keywords
automated solid-phase extraction
programmed-temperature vaporization
large-volume injection
gas chromatography/mass spectrometry
semi-volatile organic compounds
water analysis
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Corresponding Author(s):
LI Yongtao,Email:Yongtao.Li@us.ul.com
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Issue Date: 05 September 2011
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