Determination and occurrence of endocrine disrupting compounds, pharmaceuticals and personal care products in fish (<i>Morone saxatilis</i>)

doi:10.1007/s11783-014-0640-6

Front. Environ. Sci. Eng.

2015, Vol. 9

Issue (3) : 475-481 https://doi.org/10.1007/s11783-014-0640-6

RESEARCH ARTICLE

Determination and occurrence of endocrine disrupting compounds, pharmaceuticals and personal care products in fish (Morone saxatilis)

Yong YU(

), Laosheng WU

Department of Environmental Sciences, University of California, Riverside, CA 92521, USA

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Abstract

Endocrine disrupting compounds (EDCs), pharmaceuticals and personal care products (PPCPs) have attracted much attention due to widespread contamination in aquatic environment. In this study, we determined 13 EDCs and PPCPs in fish blood, bile and muscle by using gas chromatography-mass spectrometry (GC-MS). The limits of quantitation (LOQ) were in the ranges of 0.23–2.54, 0.22–2.36 ng·mL⁻¹, and 0.24–2.57 ng·g⁻¹ dry weight (dw) for fish blood, bile and muscle, respectively. Recoveries of target compounds spiked into sample matrices and passed through the entire analytical procedure ranged from 65% to 95%, from 60% to 92% and from 62% to 91% for blood, bile and muscle, respectively. The methods were applied to the analysis of fish from a lake in California. Target compounds were relatively low in bile, and only bisphenol A (BPA) and diclofenac were measurable near the LOQ. Seven of 13 compounds were detected in blood, with total concentrations up to 39 ng·mL⁻¹. Only BPA was frequently found in muscle, with mean concentration of 7.26 ng·g⁻¹ dw. The estimated daily intake of BPA through fish consumption for U.S. resident was significantly lower than the tolerable daily intake recommended by the European Food Safety Authority. This study showed that the exposure to the bisphenol A from fish diet is unlikely to pose a health risk.

Keywords endocrine disrupting compounds (EDCs) pharmaceuticals and personal care products (PPCPs) fish bisphenol A (BPA) risk assessment

Corresponding Author(s): Yong YU

Online First Date: 18 February 2014 Issue Date: 30 April 2015

Cite this article:

Yong YU,Laosheng WU. Determination and occurrence of endocrine disrupting compounds, pharmaceuticals and personal care products in fish (Morone saxatilis)[J]. Front. Environ. Sci. Eng., 2015, 9(3): 475-481.

URL:

https://academic.hep.com.cn/fese/EN/10.1007/s11783-014-0640-6
https://academic.hep.com.cn/fese/EN/Y2015/V9/I3/475

Fig.1 GC-MS-SIM chromatograms of analytes: (a) standard solution of 13 analytes, 50?ng·mL⁻¹; (b) fish blood sample

Tab.1 Analytical method performance

Fig.2 Recovery and precision of the method optimized by different solvents. EA: ethyl acetate; FA in MeOH: 1% formic acid in methanol

Tab.2 Concentrations of 13 compounds in fish

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