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Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front. Med.    2008, Vol. 2 Issue (1) : 105-107     DOI: 10.1007/s11684-008-0019-9
Genetics analysis of haptoglobin gene in Fujian Han nationality
ZOU Qilian1, LIN Ying1, LIN Xiangquan2, CHEN Yuanzhong3
1.Division of Cell Biology and Genetics, Fujian Medical University; 2.Fuzhou Children Hospital; 3.Fujian Institute of Hematology, The Affiliated Union Hospital, Fujian Medical University;
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Abstract  To study the genetic features (characteristics) of haptoglobin gene, four different age groups of Fujian Han people were investigated. The phenotypes of the haptoglobin of four different groups were analyzed by using polyacrylamide gel electrophoresis. The frequency of Hp1 in the population of Fujian Han nationality accounted for 0.340, among which children, youths, middle aged and elder groups were 0.307, 0.338, 0.363 and 0.383, respectively. The Hp0–0 phenotype frequency was 0.026 in which the four age groups accounted for 0.032, 0.046, 0.014 and 0.014, respectively. The frequency of Hp1 gene is rising with increasing age. The frequency of Hp0–0 phenotype is highest in the middle aged group and then tends to drop with increasing age.
Issue Date: 05 March 2008
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