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Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front. Med.    2008, Vol. 2 Issue (2) : 117-126    https://doi.org/10.1007/s11684-008-0022-1
Development and clinical trial of a novel bioactive bone cement
LEONG John1, LI Zhaoyang2, LU William2
1.The Open University of Hong Kong;Department of Orthopaedics and Traumatology, The University of Hong Kong; 2.Department of Orthopaedics and Traumatology, The University of Hong Kong
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Abstract Strontium (Sr) and related compounds have become more attractive in the prevention and treatment of osteoporosis. Previously, we developed a novel bioactive bone cement which is mainly composed of strontium-containing hydroxyapatite (Sr-HA) filler and bisphenol A diglycidylether dimethacrylate (Bis-GMA) resin. This bone cement is superior to conventional polymethylmethacrylate (PMMA) bone cement in bioactivity, biocompatibility, and osseointegration. It also has shown sufficient mechanical strength properties for its use in percutaneous vertebroplasty (PVP) and total hip replacement (THR). In this paper, we review the in vitro, in vivo and clinical evidence for the effectiveness of this bioactive bone cement.
Issue Date: 05 June 2008
 Cite this article:   
LI Zhaoyang,LEONG John,LU William. Development and clinical trial of a novel bioactive bone cement[J]. Front. Med., 2008, 2(2): 117-126.
 URL:  
https://academic.hep.com.cn/fmd/EN/10.1007/s11684-008-0022-1
https://academic.hep.com.cn/fmd/EN/Y2008/V2/I2/117
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