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Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front. Med.    2008, Vol. 2 Issue (2) : 174-177    https://doi.org/10.1007/s11684-008-0032-z
Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes patients
SUN Mingxiao, WANG Yao, CHI Jiamin
Department of Endocrinology & Metabolism, Beijing Hospital, Ministry of Healthy
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Abstract The modulatory effect of Xuezhikang on dyslipidemia and the preventive effect on atherosclerosis in newly diagnosed type 2 diabetic patients were studied. A prospective clinical trial was conducted to test the effectiveness of Xuezhikang in selected 201 newly diagnosed type 2 diabetic patients. All patients were randomly divided into two groups: 108 with Xuezhikang therapy and 93 without Xuezhikang therapy. The mean follow-up period was 22 months. The blood glucose and blood pressure of all patients were under control. Serum levels of total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) were significantly lowered and their decreased percentages were significantly higher in Xuezhikang therapy group (P < 0.05). The number of patients with arteria iliaca intima thickening was significantly lower in group of Xuezhikang therapy (P = 0.024). With stepwise multivariate logistic regression analysis, the decreased percentage of TG was significantly and independently related with the decreased number of patients with arteria iliaca intima thickening (P = 0.005). The study demonstrates that Xuezhikang therapy is effective on modulating dyslipidemia in newly diagnosed type 2 diabetes patients, and may be related with the improvement of early atherosclerosis.
Issue Date: 05 June 2008
 Cite this article:   
WANG Yao,SUN Mingxiao,CHI Jiamin. Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes patients[J]. Front. Med., 2008, 2(2): 174-177.
 URL:  
http://academic.hep.com.cn/fmd/EN/10.1007/s11684-008-0032-z
http://academic.hep.com.cn/fmd/EN/Y2008/V2/I2/174
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