Effect of Feixian Recipe on laminin, collagen
I and III in rats with pulmonary fibrosis induced by bleomycin

doi:10.1007/s11684-008-0060-8

Front. Med.

2008, Vol. 2

Issue (3) : 314-316 https://doi.org/10.1007/s11684-008-0060-8

Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei¹, JIANG Liangduo², ZHANG Wei², WU Jianjun³, LU Xiangfeng⁴

1.Department of Respiratory Diseases, Dongfang Hospital, Beijing University of Chinese Medicine; 2.Department of Internal Medicine, Dongzhimen Hospital, Beijing University of Chinese Medicine; 3.Department of Traditional Chinese Medicine, Beijing Royal Integrative Medicine Hospital; 4.Department of Pathology, Dongzhimen Hospital, Beijing University of Chinese Medicine

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Abstract The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats. A rat model with pulmonary fibrosis was established by intratracheal injection of bleomycin. On days 14, 28 and 45, the contents of laminin, collagen I and collagen III in lung tissue homogenate in the model group, the sham operated group, the Feixian group and the prednisone group were measured. The contents of laminin and collagen I and III were decreased significantly by the Feixian Recipe. Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.

Issue Date: 05 September 2008

Cite this article:

JIANG Liangduo,ZHANG Xiaomei,ZHANG Wei, et al. Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin[J]. Front. Med., 2008, 2(3): 314-316.

URL:

https://academic.hep.com.cn/fmd/EN/10.1007/s11684-008-0060-8
https://academic.hep.com.cn/fmd/EN/Y2008/V2/I3/314

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