Please wait a minute...
Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front. Med.    2008, Vol. 2 Issue (4) : 348-351    https://doi.org/10.1007/s11684-008-0066-2
Soy food consumption in relation to breast cancer modified by menopause status
YANG Rong1, ZHANG Bin2, YANG Shaoping2, ZHANG Dan2, DU Yukai3
1.Department of Maternal and Children Health Care, Tongji Medical College, Huazhong University of Science & Technology;Center of Wuhan Maternal and Child Health Care; 2.Center of Wuhan Maternal and Child Health Care; 3.Department of Maternal and Children Health Care, Tongji Medical College, Huazhong University of Science & Technology;
 Download: PDF(57 KB)   HTML
 Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks
Abstract It has been found that lifestyle and diet are associated with the development of cancers. The mortality of breast cancer in Wuhan city is increasing, according to the statistics of recent years. This case control study was aimed to provide data for alimentary therapeutics for breast carcinomas. It included a case group (n = 196) and an age frequency-matched control group (n = 202). A validated food frequency questionnaire was used to obtain information on usual food consumption. The results indicate that intake of soy foods more than 5 times per week was associated with a decreased risk of breast cancer, especially in premenopausal women. The adjusted OR was 0.294 [95% CI was (0.158–0.546), P = 0.000]. Our results indicate that alimentary therapeutics for breast cancer can be adjusted by status of menopause.
Issue Date: 05 December 2008
 Cite this article:   
YANG Rong,ZHANG Bin,YANG Shaoping, et al. Soy food consumption in relation to breast cancer modified by menopause status[J]. Front. Med., 2008, 2(4): 348-351.
 URL:  
https://academic.hep.com.cn/fmd/EN/10.1007/s11684-008-0066-2
https://academic.hep.com.cn/fmd/EN/Y2008/V2/I4/348
1 Brekelmans C T . Risk factors and risk reduction of breast and ovarian cancer. Curr Opin Obstet Gynecol, 2003, 15(1): 63–68.
doi:10.1097/00001703-200302000-00010
2 Ziegler R G, Hoover R N, Pike M C, Hildesheim A, Nomura A M, West D W, Wu-Williams A H, Kolonel L N, Horn-Ross P L, Rosenthal J F, Hyer M B . Migration patterns and breastcancer risk in Asian-American women. JNatl Cancer Inst, 1993, 85(22): 1819–1827.
doi:10.1093/jnci/85.22.1819
3 Wu A H, Ziegler R G, Horn-Ross P L, Nomura A M, West D W, Kolonel L N, Rosenthal J F, Hoover R N, Pike M C . Tofu andrisk of breast cancer in Asian-Americans. Cancer Epidemiol Biomarkers Prev, 1996, 5(11): 901–906
4 Divisi D, Di Tommaso S, Salvemini S, Garramone M, Crisci R . Diet and cancer. Acta Biomed, 2006, 77(2): 118–123
5 McTiernan A . Behavioralrisk factors in breast cancer: can risk be modified? Oncologist, 2003, 8(4): 326–334.
doi:10.1634/theoncologist.8-4-326
6 Willett W C . Diet and cancer: an evolving picture. JAMA, 2005, 293(2): 233–234.
doi:10.1001/jama.293.2.233
7 Wu A H, Stanczyk F Z, Martinez C, Tseng C C, Hendrich S, Murphy P, Chaikittisilpa S, Stram D O, Pike M C . A controlled2-mo dietary fat reduction and soy food supplementation study in postmenopausalwomen. Am J Clin Nutr, 2005, 81(5): 1133–1141
8 Allred C D, Allred K F, Ju Y H, Goeppinger T S, Doerge D R, Helferich W G . Soy processing influences growth of estrogen-dependentbreast cancer tumors. Carcinogenesis, 2004, 25(9): 1649–1657.
doi:10.1093/carcin/bgh178
9 Cassidy A, Bringham S, Setchell K D . Biological effects of isoflavones present in soy in premenopausalwomen: implications for the prevention of breast cancer. Am J Clin Nutr, 1994, 60(3): 333–340
10 Lu L J, Anderson K E, Grady J J, Kohen F, Nagamani M . Decreased ovarian hormones during a soyadiet: Implications for breast cancer prevention. Cancer Res, 2000, 60(15): 4112–4121
11 Dave B, Eason R R, Till S R, Geng Y, Velarde M C, Badger T M, Simmen R C . The soy isoflavone genisteinpromotes apoptosis in mammary epithelial cells by inducing the tumorsuppressor PTEN. Carcinogenesis, 2005, 26(10): 1793–1803.
doi:10.1093/carcin/bgi131
12 Pinkerton J V, Santen R . Alternatives to the use ofestrogen in postmenopausal women. EndocrRev, 1999, 20(3): 308–320.
doi:10.1210/er.20.3.308
13 Wood C E, Register T C, Franke A A, Anthony M S, Cline J M . Dietary soy isoflavones inhibitestrogen effects in the postmenopausal breast. Cancer Res, 2006, 66 (2): 1241–1249.
doi:10.1158/0008-5472.CAN-05-2067
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed