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Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

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2018 Impact Factor: 1.847

Front Med    0, Vol. Issue () : 178-184    https://doi.org/10.1007/s11684-011-0131-0
REVIEW
An introduction to the medicinal plant genome project
Shilin Chen(), Li Xiang, Xu Guo, Qiushi Li
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China
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Abstract

In recent years, genomics has developed rapidly with the application of next-generation sequencing technology. However, very few studies have been carried out on genomics for medicinal plants. This paper introduces the genome research of medicinal plants, including genome sequencing, assembly, annotation, and functional genomics, to set up the foundation for the development of natural medicines and the selection of cultivars with good agricultural traits. This study places the study on traditional Chinese medicine into the frontier field of life science.

Keywords genomics      medicinal plant      sequencing      application     
Corresponding Author(s): Chen Shilin,Email:slchen@implad.ac.cn   
Issue Date: 05 June 2011
 Cite this article:   
Shilin Chen,Li Xiang,Xu Guo, et al. An introduction to the medicinal plant genome project[J]. Front Med, 0, (): 178-184.
 URL:  
https://academic.hep.com.cn/fmd/EN/10.1007/s11684-011-0131-0
https://academic.hep.com.cn/fmd/EN/Y0/V/I/178
SpeciesGenome size (Mb)Sequencing methodsCoverage (released)Status (released)References
Glycine max1100Sanger8.0 ×DraftNature 2010;463(7278):178-183
Brachypodium distachyon272Sanger9.4 ×High-qualitydraftNature 2010;463(7282):763-768
Malus × domestica Borkh.742Sanger+ 4544.0 × + 11.4 ×High-quality draftNature Genetics 2010;Doi:10.1038/ng.654
Ricinus communis320Sanger4.6 ×DraftNature Biotechnology 2010; 28(9):951-959
Fragaria vesca240454+ Illumina+ SOLiD25.4 × + 11.7 × + 45.3 ×DraftNature Genetics 2010; Doi:10.1038/ng740
Theobroma cacao430454+ Sanger+ Illumina16.5 × + 0.2 × + 44.4 ×DraftNature Genetics 2010;Doi:10.1038/ng.736
Zea mays2300Sanger6.0 ×Improved high-qualitydraftScience 2009;326(5956):1112 - 1115
Cucumis sativus367Sanger+ Illumina4.0 × + 68.3 ×DraftNature Genetics, 2009, 41(12):1275-1281
Sorgum bicolor730Sanger8.5 ×High-qualitydraftNature 2009;457(7229):551-556
Physcomitrella patens511Sanger9.0 ×DraftScience 2008;319(5859):64-69
Carica papaya372Sanger3.0 ×DraftNature 2008;452(7190):991-996
Vitis vinifera487Sanger8.4 ×High-qualitydraftNature 2007;449(7161):463-467
Populus trichocarpa485Sanger7.5 ×DraftScience 2006;313(5793):1596-1604
Oryza sativa.indica466Sanger4.0 ×DraftScience 2002;296(5565):79-92
Oryza sativa.japonica420Sanger6.0 ×DraftScience 2002;296(5565):92-100
Arabidopsis thaliana125Sanger\DraftNature 2000;408(6814):796-815
Ganoderma lucidum48Sanger+ 454+ SOLiD\AssembledNCBI
Ganoderma sinesis60454+ SOLiD\AssembledNCBI
Salvia miltiorrhiza600454+ SOLiD\AssembledNCBI
Panax ginseng3200\\In progressNCBI
Panax Notoginseng\\\In progressNCBI
Tab.1  Completed plant genome projects and medicinal plants genome projects in progress
PlatformsRead length (bp)Throughput per run (Gb)Run time (days)Cost ($/Mb)
Roche GS FLX Titanium4000.60.35~60
Illumina Hiseq20002 × 1002008<2
ABI/SOLiD5500xl2 × 603007<2
Tab.2  Comparison of next-generation sequencing platforms
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