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Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front Med    2013, Vol. 7 Issue (3) : 277-279    https://doi.org/10.1007/s11684-013-0273-3
MINI-REVIEW
Understanding channel tropism in traditional Chinese medicine in the context of systems biology
Ping Liu, Songlin Liu, Gang Chen, Ping Wang()
Key Laboratory of Traditional Chinese Medicine Resource and Compound Prescription, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, China
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Abstract

Channel tropism is investigated and developed through long-term clinical practice. In recent years, the development of channel tropism theory has attracted increasing attention. This study analyzed channel tropism theory and the problems associated with it. Results showed that this theory and systems biology have a similar holistic viewpoint. Systems biology could provide novel insights and platform in the study of channel tropism. Some problems in channel tropism theory, including pharmacology and action mechanism, were investigated.

Keywords systems biology      channel tropism theory      traditional Chinese medicine      application     
Corresponding Author(s): Wang Ping,Email:lp_wh2008@126.com   
Issue Date: 05 September 2013
 Cite this article:   
Songlin Liu,Gang Chen,Ping Wang, et al. Understanding channel tropism in traditional Chinese medicine in the context of systems biology[J]. Front Med, 2013, 7(3): 277-279.
 URL:  
https://academic.hep.com.cn/fmd/EN/10.1007/s11684-013-0273-3
https://academic.hep.com.cn/fmd/EN/Y2013/V7/I3/277
1 Wang HM, Zhang SS , Zhao HZ. The present state and prospect of experimental study on channel tropism. Shanxi Tradit Chin Med (Shanxi Zhong Yi) 2000; 16(5): 48-50 (in Chinese)
2 Lu XC. Research ideas and method on the theory of four properties, five tastes and channel distribution in Chinese herbal. Chin J Basic Med TCM (Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi) 2006; 12(11): 803-804 (in Chinese)
3 Wang J, Liang MX. Thoughts and methods of modern research on channel distribution of Chinese herbs. Modern Trat Chin Med Mat Mat World Sci & Tech(Shi Jie Ke Xue Ji Shu—Zhong Yi Yao Xian Dai Hua) 2012; 14(1): 1237-1241 (in Chinese)
4 Chen Z. System Biology—the core driving force of 21 century medical and biological development. World Sci (Shi Jie Ke Xue) 2005; 3: 2-6 (in Chinese)
5 Qu HQ, Ai MY, Zhang B, Huang JM. Study on property theory of Chinese herbal medicine based on complex system. J Beijing Univ Tradit Chin Med (Beijing Zhong Yi Yao Da Xue Xue Bao) 2008; 31 (8): 522-525 (in Chinese)
6 Huang LM, Tang SH. Study of the theory origin and connotative meaning of channel tropism in TCM. J Tradit Chin Med (Zhong Yi Za Zhi) 2009; 50(8): 680-682 (in Chinese)
7 Zhang Y. Therapeutic action of drugs and channel tropism in TCM. Chin J Basic Med TCM (Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi) 2004; 10(8): 67-70 (in Chinese)
8 Zhao ZJ, Hu HX, Zhang XX. Study on the modernization of the meridian affinity doctrine. J Beijing Univ Tradit Chin Med (Beijing Zhong Yi Yao Da Xue Xue Bao) 2002; 24(1): 5-7 (in Chinese)
9 Wang T, Guan JH. Views of study of channel tropism of Chinese herb and disease. J Tradit Chin Med (Zhong Yi Za Zhi) 2012; 53(4): 356-357 (in Chinese)
10 Wang ZY, Liu Y. Experimental studies of channel tropism in TCM. J Zhejiang Univ Tradit Chin Med (Zhejiang Zhong Yi Yao Da Xue Xue Bao) 2004; 28(1): 79-80 (in Chinese)
11 Jia HZ, Wang ZZ. The method and limitation of experimental study of channel tropism theory. J Tradit Chin Med (Zhong Yi Za Zhi) 1998; 39(6): 369-370 (in Chinese)
12 Zhao ZJ, Chen W. The present research state and prospect of doctrine of channel distribution of Chinese medicine. J Tradit Chin Med (Zhong Yi Za Zhi) 2003; 18(1): 40-45 (in Chinese)
13 Wang GH, Xu YF, Zhang WH. Study of the distribution of active ingredients of Chinese herb to explore channel tropism theory. J Jiangxi Univ Tradit Chin Med (Jiangxi Zhong Yi Yao Da Xue Xue Bao) 1997; 9(4): 32-33 (in Chinese)
14 Liang AH, Xue BY. The status quo and prospect of experimental study on channel tropism of Chinese herbal drugs. China J Chin Materia Medica (Zhongguo Zhong Yao Za Zhi) 1996; 21(1): 58-60 (in Chinese)
pmid:8703357
15 Wang HD. Study the relationship between receptor theory and Channel tropism. J Zhejiang Univ Tradit Chin Med (Zhejiang Zhong Yi Yao Da Xue Xue Bao) 2001; 8: 324-326 (in Chinese)
16 Yuan CJ, Huang ZL. Study of channel tropism and guide theory of traditional Chinese medicine based on receptor pharmacology and vector theory. J Hubei Insti Nat(Med Edi) (Hubei Ming Zu Xue Yuan Xue Bao:Yi Xue Ban) 2000; 17(1): 30-32 (in Chinese)
17 Xu SN. Investing modern research on meridian-reaching actions of Traditional Chinese medicinal herbs. Chin Phar Bull (Zhongguo Yao Li Xue Tong Bao) 2004; 20(5): 598-600 (in Chinese)
18 Zhang ZZ. Potential crises in modernization of Chinese materia medica in systems biology era. J Shanghai Univ Tradit Chin Med (Shanghai Zhong Yi Yao Da Xue Xue Bao) 2007; 21(3): 3-6 (in Chinese)
19 Xiao C. Contribution of metabolomics study on the complex system and overall effect of Chinese herb. Chin J Nat Med (Zhongguo Tian Ran Yao Wu) .2009; 7(2): 81-85 (in Chinese)
doi: 10.3724/SP.J.1009.2009.00081
20 Zhou M, Fan Z, Jia W, Zhao AH. The integrity of traditional medicine and modern medicine——Application of Metabolomics in the study of Traditional Chinese Prescription. Chin J Nat Med (Zhongcuo Tian Ran Yao Wu) 2009; 7(2): 97-101 (in Chinese)
21 Liu CX, Si RY, Wan RZ, Lin YP, Xu YY. Metabonomics in Research of Natural Drugs and Traditional Chinese Medicines. Chin J Nat Med (Zhongguo Tian Ran Yao Wu) 2008; 6(2): 82-88 (in Chinese)
22 Sun M, Lu SM. The thought of modern study based on channel tropism theory in traditional Chinese medicine. Chin J of Inform Tradit Chin Med (Zhongguo Zhong Yi Yao Xin Xi Za Zhi) 2010; 27(5): 3-4 (in Chinese)
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