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Effect of Ca2+ complexation on oxygen partial pressure in the urinary bladder meridian of goats |
Qi WANG1(), Hongzhi JIANG1, Shengli CHEN2, Mingmin ZHANG3, Mingxing DING4, Esheng KONG5, Guangying HUANG1 |
1. Institute of Traditional Chinese & Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 2. Department of Pharmaceutical Analysis, Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China; 3. Department of Traditional Chinese & Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 4. College of Animal Breeding and Veterinary, Huazhong Agricultural University, Wuhan 430070, China; 5. Institute of Environmental Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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Abstract The aim of this paper was to explore the relationship between energy metabolism and the meridian phenomenon. The manner of change of oxygen partial pressure in acupoints and no-acupoints of the urinary bladder meridian of goats was observed with a needle-type tissue oxygen tension sensor after the acupuncture effect was blocked by Ca2+ complexation with ethylenediamine tetraacetic acid (EDTA)-Na2. The results showed that: (1) the concentration of calcium ion in urinary bladder meridian acupoints was higher than that in no-acupoints (P<0.01 or P<0.05); (2) the tissue oxygen tension in urinary bladder meridian acupoints was higher than that in no-acupoints (P<0.01); (3) the oxygen partial pressure in acupoints decreased significantly after injection with EDTA-Na2, compared with injection of either normal sodium or nothing (P<0.01); (4) the oxygen partial pressure in acupoints was higher than that in no-acupoints after EDTA-Na2 injection (P<0.01). Acupuncture could reduce oxygen partial pressure in acupoints by regulating microcirculation and increasing metabolic levels.
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Keywords
oxygen partial pressure
biosensor
calcium channels
acupoint
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Corresponding Author(s):
WANG Qi,Email:wangqixlp@hotmail.com
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Issue Date: 05 March 2009
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