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Meta-analysis of the risk factors of breast cancer
concerning reproductive factors and oral contraceptive use |
Qiong DAI MD,Bei LIU MD,Yukai DU MM, |
Department of Maternal
and Children Health Care and Adolescent Hygiene, School of Public
Health, Tongji Medical College, Huazhong University of Science and
Technology, Wuhan 430030, China; |
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Abstract The authors performed a meta-analysis of case-control studies that addressed whether reproductive factors and oral contraceptive use were associated with breast cancer by searching the MEDLINE, PubMed, Proquest, Embase, ScienceDirect, African Healthline, BMJ Health Intelligence and Chinese Periodical net databases for all English-language and Chinese-language papers published from January 1, 1997 to December 31, 2007. A total of 15 studies calculating pool ORs indicated that menopausal age >50yr [odds ratio (OR), 1.39; 95% confidence interval (CI), 1.22―1.57] and oral contraceptive use (OR, 2.12*, “*”: summary OR was adjusted; 95% CI, 1.24―3.62) were correlated with the increase in breast cancer risk while the summary OR based on number of full-term pregnancies ≥1 (OR, 0.63*; 95% CI, 0.60―0.68) and breast-feeding (OR, 0.76; 95% CI, 0.64―0.90) indicated no association with breast cancer risk. The correlation was statistically significant. Menopausal age >50yr and oral contraceptive use are positively correlated with an increase in breast cancer risk while breast-feeding and number of full-term pregnancies ≥1 are protective factors.
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Keywords
meta-analysis
breast cancer
risk factors
reproductive factors
oral contraceptive use
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Issue Date: 05 December 2009
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Li J, Liu H, Rong S Y, Niu F L, Zhang G Z, Yao S Q, Wang M Q, Zhao Q. A case-control study on environmental risk factors offemale breast cancer in Tangshan city. Zhongguo Gonggong Weisheng, 2007, 23(3): 312―314 (in Chinese)
|
|
Zhao Y, Shi Z, Liu L. Matched case-control study for detecting risk factorsfor breast cancer in women living in Chengdu. Zhonghua Liu Xing Bing Xue Za Zhi, 1999, 20(2): 91―94 (in Chinese)
|
|
Lin X Y, XU G F, Xu H, Zhao X L, Yu H X, Zhao C F. Case-control study on the risk factors of breast cancer among womenin Jinan. Shandong Daxue Xuebao (Yixueban), 2001, 39(6): 552―553 (in Chinese)
|
|
Li X F, Gao X H, Zhang C L, Cheng Y, Ma L. A conditional logistic regression analysisof risk factors of breast cancer. ZhongguoWeisheng Tongji, 2001, 18(1): 20―21 (in Chinese)
|
|
Yuan B J, Dai Y, Shi Z M, Pan X Q, Hang W S. A case-control study on risk factorsof female breast cancer. Zhongguo GonggongWeisheng, 2004, 20(9): 1036 (in Chinese)
|
|
Ursin G, London S, Yang D, Tseng C C, Pike M C, Bernstein L, Stanczyk F Z, Gentzschein E. Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratioand family history of breast cancer in premenopausal women. Breast Cancer Res Treat, 2002, 72(2): 139―143
doi: 10.1023/A:1014896417653
|
|
Li C I, Stanford J L, Daling J R. Anthropometric variables in relation to risk of breastcancer in middle-aged women. Int J Epidemiol, 2000, 29(2): 208―213
doi: 10.1093/ije/29.2.208
|
|
Sala E, Warren R, McCann J, Duffy S, Luben R, Day N. Highrisk mammographic parenchymal patterns, hormone replacement therapyand other risk factors: a cases-control study. Int J Epidemiol, 2000, 29(4): 629―636
doi: 10.1093/ije/29.4.629
|
|
Moorman P G, Kuwabara H, Millikan R C, Newman B. Menopausalhormones and breast cancer in a biracial population. Am J Public Health, 2000, 90(6): 966―971
doi: 10.2105/AJPH.90.6.966
|
|
Gomes A L, Guimarães M D, Gomes C C, Chaves I G, Gobbi H, Camargos A F. Risk factors for breast cancer among pre- or post-menopausalwomen in Belo Horizonte, Brazil. GynecolObstet Invest, 2001, 52(3): 173―179
doi: 10.1159/000052968
|
|
Petro-Nustas W, Norton M E, al-Masarweh I. Risk factors for breast cancer in Jordanian women. J Nurs Scholarsh, 2002, 34(1): 19―25
doi: 10.1111/j.1547-5069.2002.00019.x
|
|
McCormack V A, Mangtani P, Bhakta D, McMichael A J, dos Santos Silva I. Heterogeneityof breast cancer risk within the South Asian female population inEngland: a population-based case-control study of first-generationmigrants. Br J Cancer, 2004, 90(1): 160―166
doi: 10.1038/sj.bjc.6601440
|
|
Zhang Y, Wise J P, Holford T R, Xie H, Boyle P, Zahm S H, Rusiecki J, Zou K, Zhang B, Zhu Y, Owens P H, Zheng T. Serum polychlorinated biphenyls,cytochrome P-450 1A1 polymorphisms, and risk of breast cancer in Connecticutwomen. Am J Epidemiol, 2004, 160(12): 1177―1183
|
|
Lee M M, Chang I Y, Horng C F, Chang J S, Cheng S H, Huang A. Breastcancer and dietary factors in Taiwanese women. Cancer Causes Control, 2005, 16(8): 929―937
doi: 10.1007/s10552-005-4932-9
|
|
Thanos J, Cotterchio M, Boucher B A, Kreiger N, Thompson L U. Adolescent dietary phytoestrogenintake and breast cancer risk (Canada). Cancer Causes Control, 2006, 17(10): 1253―1261
doi: 10.1007/s10552-006-0062-2
|
|
Freedman L S, Potischman N, Kipnis V, Midthune D, Schatzkin A, Thompson F E, Troiano R P, Prentice R, Patterson R, Carroll R, Subar A F. A comparison of two dietaryinstruments for evaluating the fat-breast cancer relationship. Int J Epidemiol, 2006, 35(4): 1011―1021
doi: 10.1093/ije/dyl085
|
|
Rosner B, Colditz G A, Willett W C. Reproductive risk factor in a prospective study of breastcancer: the Nurses’ Health Study. Am J Epidemiol, 1994, 139: 819―835
|
|
Trichopoulos D, Hsieh C C, MacMahon B, Lin T M, Lowe C R, Mirra A P, Ravnihar B, Salber E J, Valaoras V G, Yuasa S. Age at any birth and breastcancer risk. Int J Cancer, 1983, 31(6): 701―704
doi: 10.1002/ijc.2910310604
|
|
Han D F, Ma J, Zhou X, Qiu H, Fang L, Huang S. ACase-control study on the risk of female beast cancer in Wuhan area. Zhonghua Liu Xing Bing Xue Za Zhi, 2004, 25(3): 256―260 (in Chinese)
|
|
Harris J R, Lippman M E. Diseases of the breast. 3rd ed. Lippmcott Williamand Wilkins, Inc., U S A, 2006, 214
|
|
Collaborative Group on Hormonal Factors inBreast Cancer. Breast cancer and breastfeeding:collaborative reanalysis of individual data from 47 epidemiologicalstudies in 30 countries, including 50302 women with breast cancerand 96973 women without the disease. Lancet, 2002, 360(9328): 187―195
doi: 10.1016/S0140-6736(02)09454-0
|
|
Tryggvadóttir L, Tulinius H, Eyfjord J E, Sigurvinsson T. Breastfeedingand reduced risk of breast cancer in an Icelandic cohort study. Am J Epidemiol, 2001, 154(1): 37―42
doi: 10.1093/aje/154.1.37
|
|
Jernström H, Lubinski J, Lynch H T, Ghadirian P, Neuhausen S, Isaacs C, Weber B L, Horsman D, Rosen B, Foulkes W D, Friedman E, Gershoni-Baruch R, Ainsworth P, Daly M, Garber J, Olsson H, Sun P, Narod S A. Breast-feedingand the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. J Natl Cancer Inst, 2004, 96(14): 1094―1098
|
|
Li H L. Repoductive factor and breast cancer in a population-based case-controlstudy. Zhongliu (Shanghai), 2000, 20(2): 88―91 (in Chinese)
|
|
Kahlenborn C, Modugno F, Potter D M, Severs W B. Oral contraceptive use as a risk factor for premenopausal breastcancer: a meta-analysis. Mayo Clin Proc, 2006, 81(10): 1290―1302
doi: 10.4065/81.10.1290
|
|
Thomas D B. Oral contraceptive breast cancer: review of the epidemiologic literature. Contraception, 1991, 43(6): 597―642
doi: 10.1016/0010-7824(91)90006-2
|
|
Hu J. MedicalResearch Methodology. Chengdu: Sichuan Science and Technology Press, 2007, 120
|
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