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Metformin for cancer prevention |
Yonghua Yang( ) |
| School of Pharmacy, Fudan University, Shanghai 201203, China |
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Corresponding Author(s):
Yang Yonghua,Email:yonghuayang@hotmail.com
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Issue Date: 05 June 2011
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Dowling RJ, Zakikhani M, Fantus IG, Pollak M, Sonenberg N. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. Cancer Res 2007; 67(22): 10804–10812
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Tomimoto A, Endo H, Sugiyama M, Fujisawa T, Hosono K, Takahashi H, Nakajima N, Nagashima Y, Wada K, Nakagama H, Nakajima A. Metformin suppresses intestinal polyp growth in ApcMin/+ mice. Cancer Sci 2008; 99(11): 2136–2141
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Hosono K, Endo H, Takahashi H, Sugiyama M, Sakai E, Uchiyama T, Suzuki K, Iida H, Sakamoto Y, Yoneda K, Koide T, Tokoro C, Abe Y, Inamori M, Nakagama H, Nakajima A. Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial. Cancer Prev Res (Phila) , 2010, 3(9): 1077–1083
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| 14 |
Hirsch HA, Iliopoulos D, Tsichlis P N, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 2009; 69(19): 7507–7511
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| 15 |
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doi: 10.1073/pnas.0807991106 pmid:19237574
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