Please wait a minute...
Frontiers of Medicine

ISSN 2095-0217

ISSN 2095-0225(Online)

CN 11-5983/R

Postal Subscription Code 80-967

2018 Impact Factor: 1.847

Front Med    2011, Vol. 5 Issue (2) : 134-140    https://doi.org/10.1007/s11684-011-0135-9
REVIEW
Clinical acupuncture research in the West
Xianze Meng1,3, Shifen Xu2,3, Lixing Lao3()
1. Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200001, China; 2. Shanghai Municipal Hospital of Traditional Chinese Medicine affiliated with Shanghai TCM University, Shanghai 200071, China; 3. Center for Integrative Medicine, University of Maryland School of Medicine, 520 West Lombard Street, Baltimore, MD 21201, USA
 Download: PDF(135 KB)   HTML
 Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks
Abstract

In recent years, acupuncture has rapidly become part of mainstream medicine in the West, where new developments in acupuncture clinical research show extensive progress in evaluating the efficacy and safety of the modality in many categories of disease, especially in pain conditions. Although challenges and difficulties remain, the acupuncture research community has matured and its past experience may lead to even better methods and more innovative research.

Keywords acupuncture      clinical research      research methodology      the West     
Corresponding Author(s): Lao Lixing,Email:llao@compmed.umm.edu   
Issue Date: 05 June 2011
 Cite this article:   
Xianze Meng,Shifen Xu,Lixing Lao. Clinical acupuncture research in the West[J]. Front Med, 2011, 5(2): 134-140.
 URL:  
https://academic.hep.com.cn/fmd/EN/10.1007/s11684-011-0135-9
https://academic.hep.com.cn/fmd/EN/Y2011/V5/I2/134
DisorderAuthorConclusion
Low back pain [39]Brinkhaus et al. (2006)Positive
Experimental pain [40]Barlas et al. (2006)Positive
Migraine [41]Diener et al. (2006)Negative
Migraine [42]Linde et al. (2006)Positive
Perioperative pain [43]Sator-Katzenschlager et al. (2006)Positive
Chronic neck pain [44]Witt et al. (2006)Positive
Chronic low back pain [45]Witt et al. (2006)Positive
Knee osteoarthritis [46]Scharf et al. (2006)Positive
Uncomplicated neck pain [47]Vas et al. (2006)Positive
Persistent non-specific low back pain [48]Thomas et al. (2006)Positive
Osteoarthritis of the knee or hip [49]Witt et al. (2006)Positive
Pain after third molar tooth extraction [50]Michalek-Sauberer et al. (2007)Negative
Severe knee osteoarthritis [51]Williamson et al. (2007)Positive
Osteoarthritis of the knee [52]Foster et al. (2007)Negative
Migraine [38]Facco et al. (2007)Positive
Low back pain [12]Haake et al. (2007)Positive
Tab.1  RCTs using “Wait-List” control for pain conditions (2006-2007)
DisorderAuthorConclusion
Myofascial pain [55]Shen et al. (2007)Positive
Toothache [50]Michalek-Sauberer et al. (2007)Negative
Temporomandibular joint pain [56]Smith et al. (2007)Positive
Chronic neck pain [57]Itoh et al. (2007)Positive
Postthoracotomy pain [58]Wong et al. (2006)Positive
Chronic low back pain [59]Itoh et al. (2006)Positive
Low back pain [60]Inoue et al. (2006)Positive
Tab.2  RCTs using “Non-Insertion Sham Acupuncture” control for pain conditions (2006-2007)
DisorderAuthorConclusion
Migraine prophylaxis [61]Alecrim-Andrade et al. (2006)Negative
Chronic shoulder pain [62]Dyson-Hudson et al. (2007)Positive trend
Knee osteoarthritis [46]Scharf et al. (2006)Negative
Knee pain [63]Tsang et al. (2007)Negative
Hip arthroplasty pain [64]Usichenko et al. (2006)Positive
Chronic low back pain [39]Brinkhaus et al. (2006)Negative
Migraine [41]Diener et al. (2006)Negative
Low back pain [12]Haake et al. (2007)Negative
Tab.3  RCTs using “Needling Insertion Sham Acupuncture” control for pain conditions (2006-2007)
DisorderAuthorResult
Knee osteoarthritis pain [32]Huang et al. (2010)Positive
Chronic shoulder pain [13]Molsberger et al. (2010)Positive
Chronic neck pain [67]Sahin et al. (2010)Negative
Osteoarthritis of the knee [68]Suarez-Almazor et al. (2010)Negative
Aromatase inhibitor-associated joint symptoms (joint pain and stiffness) [33]Crew et al. (2010)Positive
Opioid detoxification and pain [34]Meade et al. (2009)Positive
Low back and posterior pelvic pain in pregnant women [35]Wang et al. (2009)Positive
Delayed-onset muscle soreness [36]Hübscher M et al. (2009)Positive
Migraine pain [69]B?cker et al. (2008)Negative
Migraine pain [37]Alecrim-Andrade et al. (2008)Positive
Chronic pain [70]Zheng et al. (2008)Negative
Rheumatoid arthritis [71]Zanette et al. (2008)Negative
Migraine pain [38]Facco et al. (2008)Positive
Tab.4  RCTs using “Insertion Sham Acupuncture” control for pain conditions (2008–010)
1 Cassedy JH. Early uses of acupuncture in the United States, with an addendum (1826) by Franklin Bache, M.D. Bull N Y Acad Med 1974; 50(8): 892-906
pmid:4604365
2 NIH Consensus Conference. Acupuncture. JAMA 1998; 280(17): 1518-1524
pmid:9809733
3 Turner JS. The regulation of acupuncture needles by the United States Food and Drug Administration. J Altern Complement Med 1995; 1(1): 15-16
doi: 10.1089/acm.1995.1.15 pmid:9395599
4 Nahin RL, Barnes PM, Stussman BJ, Bloom B. Costs of complementary and alternative medicine (CAM) and frequency of visits to CAM practitioners: United States, 2007. Natl Health Stat Report 2009; (18): 1-14
5 Barnes PM, Powell-Griner E, McFann K, Nahin RL. Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004; 2004(343): 1-19
pmid:15188733
6 Barnes PM, Bloom B, Nahin RL. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health. Stat Report 2009; (12): 1-23
7 Han JS, Ho YS. Global trends and performances of acupuncture research. Neurosci Biobehav Rev 2011; 35(3): 680-687
doi: 10.1016/j.neubiorev.2010.08.006 pmid:20800613
8 Mao JJ, Kapur R. Acupuncture in primary care. Prim Care 2010; 37(1): 105-117
pmid:20189001
9 Berman BM, Lao L, Langenberg P, Lee WL, Gilpin AM, Hochberg MC. Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial. Ann Intern Med 2004; 141(12): 901-910
pmid:15611487
10 Jubb RW, Tukmachi ES, Jones PW, Dempsey E, Waterhouse L, Brailsford S. A blinded randomised trial of acupuncture (manual and electroacupuncture) compared with a non-penetrating sham for the symptoms of osteoarthritis of the knee. Acupunct Med 2008; 26(2): 69-78
doi: 10.1136/aim.26.2.69 pmid:18591906
11 Cherkin DC, Sherman KJ, Avins AL, Erro JH, Ichikawa L, Barlow WE, Delaney K, Hawkes R, Hamilton L, Pressman A, Khalsa PS, Deyo RA. A randomized trial comparing acupuncture, simulated acupuncture, and usual care for chronic low back pain. Arch Intern Med 2009; 169(9): 858-866
doi: 10.1001/archinternmed.2009.65 pmid:19433697
12 Haake M, Müller HH, Schade-Brittinger C, Basler HD, Sch?fer H, Maier C, Endres HG, Trampisch HJ, Molsberger A. German Acupuncture Trials (GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups. Arch Intern Med 2007; 167(17): 1892-1898
doi: 10.1001/archinte.167.17.1892 pmid:17893311
13 Molsberger AF, Schneider T, Gotthardt H, Drabik A. German Randomized Acupuncture Trial for chronic shoulder pain (GRASP) – a pragmatic, controlled, patient-blinded, multi-centre trial in an outpatient care environment. Pain 2010; 151(1): 146-154
doi: 10.1016/j.pain.2010.06.036 pmid:20655660
14 Madsen MV, G?tzsche PC, Hróbjartsson A. Acupuncture treatment for pain: systematic review of randomised clinical trials with acupuncture, placebo acupuncture, and no acupuncture groups. BMJ 2009; 338: a3115
doi: 10.1136/bmj.a3115 pmid:19174438
15 Manheimer E, White A, Berman B, Forys K, Ernst E. Meta-analysis: acupuncture for low back pain. Ann Intern Med 2005; 142(8): 651-663
pmid:15838072
16 Manheimer E, Cheng K, Linde K, Lao L, Yoo J, Wieland S, van der Windt DA, Berman BM, Bouter LM. Acupuncture for peripheral joint osteoarthritis. Cochrane Database Syst Rev 2010; (1): CD001977
pmid:20091527
17 Trinh KV, Phillips SD, Ho E, Damsma K. Acupuncture for the alleviation of lateral epicondyle pain: a systematic review. Rheumatology (Oxford) 2004; 43(9): 1085-1090
doi: 10.1093/rheumatology/keh247 pmid:15213328
18 Ernst E, Pittler MH. The effectiveness of acupuncture in treating acute dental pain: a systematic review. Br Dent J 1998; 184(9): 443-447
doi: 10.1038/sj.bdj.4809654 pmid:9617000
19 Linde K, Allais G, Brinkhaus B, Manheimer E, Vickers A, White AR. Acupuncture for migraine prophylaxis. Cochrane Database Syst Rev 2009; (1): CD001218
pmid:19160193
20 Manber R, Schnyer RN, Lyell D, Chambers AS, Caughey AB, Druzin M, Carlyle E, Celio C, Gress JL, Huang MI, Kalista T, Martin-Okada R, Allen JJ. Acupuncture for depression during pregnancy: a randomized controlled trial. Obstet Gynecol 2010; 115(3): 511-520
doi: 10.1097/AOG.0b013e3181cc0816 pmid:20177281
21 Lee A, Fan LT. Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev 2009; (2): CD003281
pmid:19370583
22 Ezzo JM, Richardson MA, Vickers A, Allen C, Dibble SL, Issell BF, Lao L, Pearl M, Ramirez G, Roscoe J, Shen J, Shivnan JC, Streitberger K, Treish I, Zhang G. Acupuncture-point stimulation for chemotherapy-induced nausea or vomiting. Cochrane Database Syst Rev 2006; (2): CD002285
pmid:16625560
23 Helmreich RJ, Shiao SY, Dune LS. Meta-analysis of acustimulation effects on nausea and vomiting in pregnant women. Explore (NY) 2006; 2(5): 412-421
doi: 10.1016/j.explore.2006.06.002 pmid:16979105
24 Shiao SY, Dune LS. Metaanalyses of acustimulations: effects on nausea and vomiting in postoperative adult patients. Explore (NY) 2006; 2(3): 202-215
doi: 10.1016/j.explore.2006.02.005 pmid:16781643
25 Dune LS, Shiao SY. Metaanalysis of acustimulation effects on postoperative nausea and vomiting in children. Explore (NY) 2006; 2(4): 314-320
doi: 10.1016/j.explore.2006.04.004 pmid:16846819
26 Cao H, Pan X, Li H, Liu J. Acupuncture for treatment of insomnia: a systematic review of randomized controlled trials. J Altern Complement Med 2009; 15(11): 1171-1186
doi: 10.1089/acm.2009.0041 pmid:19922248
27 Han JS. Acupuncture analgesia: Areas of consensus and controversy. Pain 2011; 152(3 Suppl): s41–48
28 Dhond RP, Kettner N, Napadow V. Neuroimaging acupuncture effects in the human brain. J Altern Complement Med 2007; 13(6): 603-616
doi: 10.1089/acm.2007.7040 pmid:17718643
29 Asghar AU, Green G, Lythgoe MF, Lewith G, MacPherson H. Acupuncture needling sensation: the neural correlates of deqi using fMRI. Brain Res 2010; 1315: 111-118
doi: 10.1016/j.brainres.2009.12.019 pmid:20025853
30 Langevin HM, Bouffard NA, Badger GJ, Churchill DL, Howe AK. Subcutaneous tissue fibroblast cytoskeletal remodeling induced by acupuncture: evidence for a mechanotransduction-based mechanism. J Cell Physiol 2006; 207(3): 767-774
doi: 10.1002/jcp.20623 pmid:16511830
31 Langevin HM, Hammerschlag R, Lao L, Napadow V, Schnyer RN, Sherman KJ. Controversies in acupuncture research: selection of controls and outcome measures in acupuncture clinical trials. J Altern Complement Med 2006; 12(10): 943-953
doi: 10.1089/acm.2006.12.943 pmid:17212566
32 Huang W, Bliwise DL, Carnevale CV, Kutner NG. Acupuncture for pain and sleep in knee osteoarthritis. J Am Geriatr Soc 2010; 58(6): 1218-1220
doi: 10.1111/j.1532-5415.2010.02886.x pmid:20722870
33 Crew KD, Capodice JL, Greenlee H, Brafman L, Fuentes D, Awad D, Yann Tsai W, Hershman DL. Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer. J Clin Oncol 2010; 28(7): 1154-1160
doi: 10.1200/JCO.2009.23.4708 pmid:20100963
34 Meade CS, Lukas SE, McDonald LJ, Fitzmaurice GM, Eldridge JA, Merrill N, Weiss RD. A randomized trial of transcutaneous electric acupoint stimulation as adjunctive treatment for opioid detoxification. J Subst Abuse Treat 2010; 38(1): 12-21
doi: 10.1016/j.jsat.2009.05.010 pmid:19574017
35 Wang SM, Dezinno P, Lin EC, Lin H, Yue JJ, Berman MR. Auricular acupuncture as a treatment for pregnant women who have low back and posterior pelvic pain: a pilot study. Am J Obstet Gynecol 2009; 201(3):271.e1-9 .
36 Hübscher M, Vogt L, Bernh?rster M, Rosenhagen A, Banzer W. Effects of acupuncture on symptoms and muscle function in delayed-onset muscle soreness. J Altern Complement Med 2008; 14(8): 1011-1016
doi: 10.1089/acm.2008.0173 pmid: PMID:18990049
37 Alecrim-Andrade J, Maciel-Júnior JA, Carnè X, Severino Vasconcelos GM, Correa-Filho HR. Acupuncture in migraine prevention: a randomized sham controlled study with 6-months posttreatment follow-up. Clin J Pain 2008; 24(2): 98-105
doi: 10.1097/AJP.0b013e3181590d66 pmid:18209514
38 Facco E, Liguori A, Petti F, Zanette G, Coluzzi F, De Nardin M, Mattia C. Traditional acupuncture in migraine: a controlled, randomized study. Headache 2008; 48(3): 398-407
doi: 10.1111/j.1526-4610.2007.00916.x pmid:17868354
39 Brinkhaus B, Witt CM, Jena S, Linde K, Streng A, Wagenpfeil S, Irnich D, Walther HU, Melchart D, Willich SN. Acupuncture in patients with chronic low back pain: a randomized controlled trial. Arch Intern Med 2006; 166(4): 450-457
doi: 10.1001/.450 pmid:16505266
40 Barlas P, Ting SL, Chesterton LS, Jones PW, Sim J. Effects of intensity of electroacupuncture upon experimental pain in healthy human volunteers: a randomized, double-blind, placebo-controlled study. Pain 2006; 122(1-2): 81-89
doi: 10.1016/j.pain.2006.01.012 pmid:16527396
41 Diener HC, Kronfeld K, Boewing G, Lungenhausen M, Maier C, Molsberger A, Tegenthoff M, Trampisch HJ, Zenz M, Meinert R. Efficacy of acupuncture for the prophylaxis of migraine: a multicentre randomised controlled clinical trial. Lancet Neurol 2006; 5(4): 310-316
doi: 10.1016/S1474-4422(06)70382-9 pmid:16545747
42 Linde K, Streng A, Hoppe A, Brinkhaus B, Witt CM, Hammes M, Irnich D, Hummelsberger J, Willich SN, Melchart D. Treatment in a randomized multicenter trial of acupuncture for migraine (ART migraine). Forsch Komplement Med 2006; 13(2): 101-108
doi: 10.1159/000091999 pmid:16645290
43 Sator-Katzenschlager SM, W?lfler MM, Kozek-Langenecker SA, Sator K, Sator PG, Li B, Heinze G, Sator MO. Auricular electro-acupuncture as an additional perioperative analgesic method during oocyte aspiration in IVF treatment. Hum Reprod 2006; 21(8): 2114-2120
doi: 10.1093/humrep/del110 pmid:16679325
44 Witt CM, Jena S, Brinkhaus B, Liecker B, Wegscheider K, Willich SN. Acupuncture for patients with chronic neck pain. Pain 2006; 125(1-2): 98-106
doi: 10.1016/j.pain.2006.05.013 pmid:16781068
45 Witt CM, Jena S, Selim D, Brinkhaus B, Reinhold T, Wruck K, Liecker B, Linde K, Wegscheider K, Willich SN. Pragmatic randomized trial evaluating the clinical and economic effectiveness of acupuncture for chronic low back pain. Am J Epidemiol 2006; 164(5): 487-496
doi: 10.1093/aje/kwj224 pmid:16798792
46 Scharf HP, Mansmann U, Streitberger K, Witte S, Kr?mer J, Maier C, Trampisch HJ, Victor N. Acupuncture and knee osteoarthritis: a three-armed randomized trial. Ann Intern Med 2006; 145(1): 12-20
pmid:16818924
47 Vas J, Perea-Milla E, Mández C, Sónchez Navarro C, León Rubio JM, Brioso M, García Obrero I. Efficacy and safety of acupuncture for chronic uncomplicated neck pain: a randomised controlled study. Pain 2006; 126(1-3): 245-255
doi:10.1016/j.pain.2006.07.002 PMID:16934402
48 Thomas KJ, MacPherson H, Thorpe L, Brazier J, Fitter M, Campbell MJ, Roman M, Walters SJ, Nicholl J. Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain. BMJ 2006; 333(7569): 623
doi: 10.1136/bmj.38878.907361.7C pmid:16980316
49 Witt CM, Jena S, Brinkhaus B, Liecker B, Wegscheider K, Willich SN. Acupuncture in patients with osteoarthritis of the knee or hip: a randomized, controlled trial with an additional nonrandomized arm. Arthritis Rheum 2006; 54(11): 3485-3493
doi: 10.1002/art.22154 pmid:17075849
50 Michalek-Sauberer A, Heinzl H, Sator-Katzenschlager SM, Monov G, Knolle E, Kress HG. Perioperative auricular electroacupuncture has no effect on pain and analgesic consumption after third molar tooth extraction. Anesth Analg 2007; 104(3): 542-547
doi: 10.1213/01.ane.0000253233.51490.dd pmid:17312205
51 Williamson L, Wyatt MR, Yein K, Melton JT. Severe knee osteoarthritis: a randomized controlled trial of acupuncture, physiotherapy (supervised exercise) and standard management for patients awaiting knee replacement. Rheumatology (Oxford) 2007; 46(9): 1445-1449
doi: 10.1093/rheumatology/kem119 pmid:17604311
52 Foster NE, Thomas E, Barlas P, Hill JC, Young J, Mason E, Hay EM. Acupuncture as an adjunct to exercise based physiotherapy for osteoarthritis of the knee: randomised controlled trial. BMJ 2007; 335(7617): 436
doi: 10.1136/bmj.39280.509803.BE pmid:17699546
53 Goldman RH, Stason WB, Park SK, Kim R, Schnyer RN, Davis RB, Legedza AT, Kaptchuk TJ. Acupuncture for treatment of persistent arm pain due to repetitive use: a randomized controlled clinical trial. Clin J Pain 2008; 24(3): 211-218
doi: 10.1097/AJP.0b013e31815ec20f pmid:18287826
54 Lao LX. Acupuncture clinical studies and evidence-based medicine—an update. Acupunct Res (Zhen Ci Yan Jiu) 2008; 33(1): 53-61
pmid:18386647(in Chinese)
55 Shen YF, Goddard G. The short-term effects of acupuncture on myofascial pain patients after clenching. Pain Pract 2007; 7(3): 256-264
doi: 10.1111/j.1533-2500.2007.00140.x pmid:17714105
56 Smith P, Mosscrop D, Davies S, Sloan P, Al-Ani Z. The efficacy of acupuncture in the treatment of temporomandibular joint myofascial pain: a randomised controlled trial. J Dent 2007; 35(3): 259-267
doi: 10.1016/j.jdent.2006.09.004 pmid:17095133
57 Itoh K, Katsumi Y, Hirota S, Kitakoji H. Randomised trial of trigger point acupuncture compared with other acupuncture for treatment of chronic neck pain. Complement Ther Med 2007; 15(3): 172-179
doi: 10.1016/j.ctim.2006.05.003 pmid:17709062
58 Wong RH, Lee TW, Sihoe AD, Wan IY, Ng CS, Chan SK, Wong WW, Liang YM, Yim AP. Analgesic effect of electroacupuncture in postthoracotomy pain: a prospective randomized trial. Ann Thorac Surg 2006; 81(6): 2031-2036
doi: 10.1016/j.athoracsur.2005.12.064 pmid:16731125
59 Itoh K, Katsumi Y, Hirota S, Kitakoji H. Effects of trigger point acupuncture on chronic low back pain in elderly patients—a sham-controlled randomised trial. Acupunct Med 2006; 24(1): 5-12
doi: 10.1136/aim.24.1.5 pmid:16618043
60 Inoue M, Kitakoji H, Ishizaki N, Tawa M, Yano T, Katsumi Y, Kawakita K. Relief of low back pain immediately after acupuncture treatment—a randomised, placebo controlled trial. Acupunct Med 2006; 24(3): 103-108
doi: 10.1136/aim.24.3.103 pmid:17013356
62 Dyson-Hudson TA, Kadar P, LaFountaine M, Emmons R, Kirshblum SC, Tulsky D, Komaroff E. Acupuncture for chronic shoulder pain in persons with spinal cord injury: a small-scale clinical trial. Arch Phys Med Rehabil 2007; 88(10): 1276-1283
doi:10.1016/j.apmr.2007.06.014 PMID:17908569
63 Tsang RC, Tsang PL, Ko CY, Kong BC, Lee WY, Yip HT. Effects of acupuncture and sham acupuncture in addition to physiotherapy in patients undergoing bilateral total knee arthroplasty—a randomized controlled trial. Clin Rehabil 2007; 21(8): 719-728
doi:10.1177/0269215507077362
pmid:17846072
64 Usichenko TI, Dinse M, Lysenyuk VP, Wendt M, Pavlovic D, Lehmann C. Auricular acupuncture reduces intraoperative fentanyl requirement during hip arthroplasty—a randomized double-blinded study. Acupunct Electrother Res 2006; 31(3-4): 213-221
pmid:17608061
65 Bing Z, Villanueva L, Le Bars D. Acupuncture and diffuse noxious inhibitory controls: naloxone-reversible depression of activities of trigeminal convergent neurons. Neuroscience 1990; 37(3): 809-818
doi: 10.1016/0306-4522(90)90110-P pmid:2247225
66 Langevin HM, Wayne PM, Macpherson H, Schnyer R, Milley RM, Napadow V, Lao L, Park J, Harris RE, Cohen M, Sherman KJ, Haramati A, Hammerschlag R. Paradoxes in acupuncture research: strategies for moving forward. Evid Based Complement Alternat Med 2011; 2011: 1–11
67 Sahin N, Ozcan E, Sezen K, Karatas O, Issever H. Efficacy of acupunture in patients with chronic neck pain—a randomised, sham controlled trial. Acupunct Electrother Res 2010; 35(1-2): 17-27
pmid:20578644
68 Suarez-Almazor ME, Looney C, Liu Y, Cox V, Pietz K, Marcus DM, Street RL Jr. A randomized controlled trial of acupuncture for osteoarthritis of the knee: effects of patient-provider communication. Arthritis Care Res (Hoboken) 2010; 62(9): 1229-1236
doi: 10.1002/acr.20225 pmid:20506122
69 B?cker M, Grossman P, Schneider J, Michalsen A, Knoblauch N, Tan L, Niggemeyer C, Linde K, Melchart D, Dobos GJ. Acupuncture in migraine: investigation of autonomic effects. Clin J Pain 2008; 24(2): 106-115
pmid:18209515
70 Zheng Z, Guo RJ, Helme RD, Muir A, Da Costa C, Xue CC. The effect of electroacupuncture on opioid-like medication consumption by chronic pain patients: a pilot randomized controlled clinical trial. Eur J Pain 2008; 12(5): 671-676
doi: 10.1016/j.ejpain.2007.10.003 pmid:18035566
71 Zanette SA, Born IG, Brenol JC, Xavier RM. A pilot study of acupuncture as adjunctive treatment of rheumatoid arthritis. Clin Rheumatol 2008; 27(5): 627-635
doi: 10.1007/s10067-007-0759-y pmid:17989918
[1] Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung Jang, Younbyoung Chae. Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural network model[J]. Front. Med., 2019, 13(1): 112-120.
[2] Hujie Song, Xiao Chen, Yalan Yu, Ling Zhang. Xingnao Kaiqiao acupuncture combined with Angong Niuhuang Wan for a patient under persistent vegetative state: a case report[J]. Front. Med., 2018, 12(3): 334-339.
[3] Hong Zhao, Fengxia Liang, Yigong Fang, Baoyan Liu. Application of Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to the guideline development for clinical practice with acupuncture and moxibustion[J]. Front. Med., 2017, 11(4): 590-594.
[4] Likun Yang,Yang Wang,Qian Mo,Zhishun Liu. A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder symptoms[J]. Front. Med., 2017, 11(1): 129-136.
[5] Juanjuan Xin,Yangshuai Su,Zhaokun Yang,Wei He,Hong Shi,Xiaoyu Wang,Ling Hu,Xiaochun Yu,Xianghong Jing,Bing Zhu. Distinct roles of ASIC3 and TRPV1 receptors in electroacupuncture-induced segmental and systemic analgesia[J]. Front. Med., 2016, 10(4): 465-472.
[6] Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu. Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional Chinese medicine[J]. Front. Med., 2014, 8(3): 300-309.
[7] Guozheng Li,Xuewen Zuo,Baoyan Liu. Scientific computation of big data in real-world clinical research[J]. Front. Med., 2014, 8(3): 310-315.
[8] Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo. Construction of a shared system-based real-world clinical research system[J]. Front. Med., 2014, 8(3): 382-388.
[9] Peijing Rong, Bing Zhu, Yuqing Li, Xinyan Gao, Hui Ben, Yanhua Li, Liang Li, Wei He, Rupeng Liu, Lingling Yu. Mechanism of acupuncture regulating visceral sensation and mobility[J]. Front Med, 2011, 5(2): 151-156.
[10] Jisheng Han, Cailian Cui, Liuzhen Wu. Acupuncture-related techniques for the treatment of opiate addiction: a case of translational medicine[J]. Front Med, 2011, 5(2): 141-150.
[11] Cuihong ZHENG, Yunxia WU, Guangying HUANG, Wei WANG. Gene silencing efficiency of shRNA expression vectors targeting Cx43 in vitro[J]. Front Med Chin, 2009, 3(2): 130-135.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed