Simultaneous acquisition of CT angiography and whole brain CT perfusion images by using multiphase dynamic helical scan on 16 MDCT

doi:10.1007/s11684-009-0023-8

Front Med Chin

2009, Vol. 3

Issue (2) : 230-235 https://doi.org/10.1007/s11684-009-0023-8

RESEARCH ARTICLE

Simultaneous acquisition of CT angiography and whole brain CT perfusion images by using multiphase dynamic helical scan on 16 MDCT

Weiwei CHEN(

), Jianpin QI, Wenzhen ZHU, Wenhua HUANG, Jinmei SONG

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

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Abstract

We implemented a new protocol — multiphase dynamic helical scan to acquire CT angiography (CTA) and whole brain CT perfusion (CTP) images simultaneously with single scan on 16 multidetector CT (MDCT). A total of 90 patients who were randomly assigned into 3 groups were included in our study. Each group underwent CT scan by using the new protocol, traditional CTA and CTP protocol, respectively. The image quality of CTA, the CTP parameter values and the X-ray doses were measured and compared between the new protocol and the traditional protocols. There was no statistically significant difference in the CTA image quality between the above methods (P=0.55). For CTP parameters, the new protocol tended to overestimate the blood volume (BV) and blood flow (BF) value, and to underestimate the mean transit time (MTT) value compared with the traditional method. However, there was no statistically significant difference in BV, BF, and MTT value between the two methods except permeability surface (PS) (P>0.05). The volume CT dose index (CTDIvol) and dose length product (DLP) of our protocol were lower than the traditional one. The new protocol can obtain valuable diagnostic information in a shorter time without significant compromise in image quality. In addition, it reduces the radiation dose as well as contrast medium usage on the patient.

Keywords computed tomography angiography computed tomography perfusion

Corresponding Author(s): CHEN Weiwei,Email:chenweiwei@yahoo.cn

Issue Date: 05 June 2009

Cite this article:

Jianpin QI,Wenzhen ZHU,Wenhua HUANG, et al. Simultaneous acquisition of CT angiography and whole brain CT perfusion images by using multiphase dynamic helical scan on 16 MDCT[J]. Front Med Chin, 2009, 3(2): 230-235.

URL:

https://academic.hep.com.cn/fmd/EN/10.1007/s11684-009-0023-8
https://academic.hep.com.cn/fmd/EN/Y2009/V3/I2/230

Tab.1 Parameters of different scan protocols

Fig.1 A 40-year-old woman suffered from astrocytoma (grade III) was included in group 1. (a) CTP images of the whole brain depicted the outline and hemodynamic change of a tumor in the deep right temporal region. (b), (c), and (d) CTA images (VR and MIP) show the feeding vessels (arrow) and displacement of M1, M2 segments of right middle cerebral artery (arrowhead).

Fig.2 CTP images of the two methods. (a) and (b) show the CTP images gained by multiphase dynamic helical scan and traditional method, respectively. We chose only one slice from the whole brain CTP images here to compare the image quality with the traditional method. Both of the CTP images of the two methods could show the location and hemodynamic change of the tumor clearly.

Tab.2 Comparison of the values of CTP parameters of the two methods

Fig.3 CTA images gained by two methods. (a) CTA images gained by multiphase dynamic helical scan. The CTP images gained simultaneously of this patient are shown in Fig. 2a. (b) CTA images gained by traditional method. Both show the abundant abnormal vessels and the main feeding arteries clearly.

Tab.3 Diagnostic image quality of cerebral arteries in different scan protocols

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