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Journal of Translational Neuroscience(转化神经科学电子杂志)

ISSN 2096-0689

CN 11-9363/R

Journal of Translational Neuroscience    2020, Vol. 5 Issue (1) : 27-32    https://doi.org/10.3868/j.issn.2096-0689.2020.01.004
Case Report
Clinical features and literature review of Cogan’s syndrome with bilateral internal carotid artery occlusion
Yi Bao, Quanying Liu, Xiaoling Wang, Ying Wang, Miao Zhang, Juan Xuan, Guangjian Liu
Department of Neurology, Taihe Hospital Affiliated to Hubei University of Medicine, Shiyan, Hubei 442000, China
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Abstract Cogan’s syndrome is rare. The purpose of this article is to describe a Cogan’s syndrome case characterized by bilateral internal carotid artery occlusion and to review the literature. Treatment remedies: we showed a patient with vertigo, nausea and retching, blurred vision, unclear speech. And the whole cerebral angiogram of the patient showed bilateral internal carotid artery occlusion without obvious neurological deficit. After differential diagnosis, compared with classic Cogan’s syndrome, granulomatous polyvasculitis (GPA), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), the patient was considered as Cogan’s syndrome. Post treatment evaluating: the patient did not significantly improve vertigo after vascular bypass therapy. Conclusions: Cogan’s syndrome may cause severe vascular occlusion. The patient had no clinical symptoms; and the chronic occlusion caused by vascular inflammation may be the reason, so that there was enough time for compensation.
Keywords Cogan’s syndrome      granulomatous polyvasculitis (GPA)      digital subtraction angiography (DSA)      compensation      artery occlusion     
Issue Date: 30 March 2020
 Cite this article:   
Yi Bao, Quanying Liu, Xiaoling Wang, Ying Wang, Miao Zhang, Juan Xuan, Guangjian Liu. Clinical features and literature review of Cogan’s syndrome with bilateral internal carotid artery occlusion[J]. Journal of Translational Neuroscience,2020, 5(1): 27-32.
 URL:  
https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2020.01.004
https://academic.hep.com.cn/jtn/EN/Y2020/V5/I1/27
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[2] Yi Bao, Lixia Ma, Xiaodong Liu, Guangjian Liu, Ying Wang. Clinical characteristics and treatment strategies of acute ischemic stroke with internal carotid artery occlusion: a case report[J]. Journal of Translational Neuroscience, 2019, 4(2): 31-38.
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