ISBN:978-7-04-017675-9
出版时间:2006-04-28
语种:
开本:16
页数:582
基因的表达与调控
作 者:马骏 主编
定价:  128.00元 购买
  • 内容简介

    Jun Ma is an Associate Professor at the Division of Developmental Biology,Cincinnati Children’s Hospital Research Foundation and University of Cincinnati College of Medicine.He graduated from Peking University in 1982,majoring in Biology.He did his graduate work with Mark Ptashne at the Department of Biochemistry and Molecular Biology in Harvard University,and was a Junior Fellow at the Harvard Society of Fellows between 1989-1992.He spent the summer of 1988 in the laboratory of Christiane Nüsslein-Volhard at the Max-Planck-Institute for Developmental Biology in Tübingen to collaborate with Wolfgang Driever.He joined the faculty of the University of Cincinnati College of Medicine in 1992 and has remained there since.Currently he also has a collaborative base at the Institute of Biophysics of the Chinese Academy of Sciences in Beijing.His earlier work on the yeast activator GAL4 helped pave the way to the development of the yeast two-hybrid system.His current research focuses on the mechanisms of transcript on control and development in Drosophila.

关键词 生物类
目录
内封   
PDF (187 KB) (
版权   
PDF (269 KB) (
目录   
PDF (39 KB) (
front matter   
PDF (35 KB) (
Section I The History
Chapter01 Transcription: The Never Ending Story   
摘要   PDF (469 KB) ( ) P. 3-18
Section II The Machinery
Chapter02 The General Transcription Machinery and Preinitiation Complex Formation   
摘要   PDF (413 KB) ( ) P. 21-48
Chapter03 The Dynamic Association of RNA Polymerase II with Initiation, Elongation, and RNA Processing Factors during the Transcription Cycle   
摘要   PDF (365 KB) ( ) P. 49-66
Chapter04 General Cofactors:TFIID, Mediator and USA   
摘要   PDF (499 KB) ( ) P. 67-94
Chapter05 Chromatin and Regulation of Gene Expression   
摘要   PDF (403 KB) ( ) P. 95-110
Chapter06 HATs and HDACs   
摘要   PDF (329 KB) ( ) P. 111-134
Chapter07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription   
摘要   PDF (205 KB) ( ) P. 135-144
Section III The Regulators
Chapter08 Transcriptional Activators and Activation Mechanisms   
摘要   PDF (197 KB) ( ) P. 147-158
Chapter09 Transcriptional Repressors and Repression Mechanisms   
摘要   PDF (292 KB) ( ) P. 159-174
Chapter10 STATs in Cytokine-mediated Transcriptional Regulation   
摘要   PDF (206 KB) ( ) P. 175-184
Chapter11 Transcriptional Regulation by Smads   
摘要   PDF (455 KB) ( ) P. 185-206
Chapter12 The Rb and E2F Families of Proteins   
摘要   PDF (254 KB) ( ) P. 207-218
Chapter13 c-Jun:A Complex Tale of a Simple Transcription Factor   
摘要   PDF (385 KB) ( ) P. 219-238
Chapter14 HIV Tat and the Control of Transcriptional Elongation   
摘要   PDF (445 KB) ( ) P. 239-256
Chapter15 Post-translational Modifications of the p53 Transcription Factor   
摘要   PDF (388 KB) ( ) P. 257-272
Chapter16 Actions of Nuclear Receptors   
摘要   PDF (288 KB) ( ) P. 273-292
Chapter17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators   
摘要   PDF (511 KB) ( ) P. 293-308
Chapter18 Hox Genes   
摘要   PDF (245 KB) ( ) P. 309-320
Chapter19 Nuclear Factor-kappa B   
摘要   PDF (257 KB) ( ) P. 321-328
Chapter20 The ATF Transcription Factors in Cellular Adaptive Responses   
摘要   PDF (388 KB) ( ) P. 329-340
Section IV The Genome
Chapter21 Function and Mechanism of Chromatin Boundaries   
摘要   PDF (498 KB) ( ) P. 343-3
Chapter22 Heterochromatin and X Inactivation   
摘要   PDF (230 KB) ( ) P. 365-376
Chapter23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development   
摘要   PDF (312 KB) ( ) P. 377-392
Chapter24 Comparative Genomics of Tissue Specific Gene Expression   
摘要   PDF (488 KB) ( ) P. 393-408
Chapter25 Transcription and Genomic Integrity   
摘要   PDF (424 KB) ( ) P. 409-430
Chapter26 Cell Death and Transcription   
摘要   PDF (344 KB) ( ) P. 431-444
Section V Special Topics
Chapter27 Pre-mRNA Splicing in Eukaryotic Cells   
摘要   PDF (570 KB) ( ) P. 447-468
Chapter28 Genome Organization:The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation   
摘要   PDF (232 KB) ( ) P. 469-480
Chapter29 The Biogenesis and Function of MicroRNAs   
摘要   PDF (341 KB) ( ) P. 481-492
Chapter30 Transcription Factor Dynamics   
摘要   PDF (398 KB) ( ) P. 493-502
Chapter31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control   
摘要   PDF (335 KB) ( ) P. 503-518
Chapter32 Wnt Signaling and Transcriptional Regulation   
摘要   PDF (485 KB) ( ) P. 519-532
Chapter33 Regulatory Mechanisms for Floral Organ Identity Specification in Arabidopsis thaliana   
摘要   PDF (429 KB) ( ) P. 533-548
Chapter34 Transcription Control in Bacteria   
摘要   PDF (565 KB) ( ) P. 549-564
Chapter35 Gene Therapy:Back to the Basics   
摘要   PDF (264 KB) ( ) P. 565-582