Chapter 34 Basic Mechanisms of Clinically Used Drugs(Annika B. Malmberg)

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Molecular Pain 作者：Min Zhuo Ed.　　 ISBN：978-7-04-018954-4　出版时间：2007-11-04

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Front Matter

Part Ⅰ Genes, Neurons and Neurotransmission

Chapter 1 Genes and Neurons (Bong-Kiun Kaang)

Chapter 2 Synapses: Coupling of PresynapttcVoltage-gated Ca 2+Channels to Vesicular Release of Neurotransmitter (Lu-Yang Wang)

Chapter 3 Synaptic Vesicle Cycle at Nerve Terminals(Ling-Gang Wu, Jianhua Xu)

Part Ⅱ Glutamate, Excitatory Transmission and Pain

Chapter 4 Postsynaptic Excitatory Transmission (John F.MacDonald, Suhas Kotecha, Michael F.Jackson, Michael Beazely)

Chapter 5 Kainate Receptors (Christophe Mulle)

Chapter 6 Excitatory Amino Acid Neurotransmitter Regulation (Rochelle Hines, Alaa EI-Husseini )

Chapter 7 Spinal Glutamate Receptors (Megumu Yoshimura)

Chapter 8 Glutamate Kainate Receptor in Pam Transmission and Modulation（Min Zhuo)

Part Ⅲ Neuropeptides, ATP, Retrograde Messengers and Opioids

Chapter 9 Neuropeptides（Xu Zhang, Lan Bao)

Chapter 10 ATP and Its Receptors in Pain (Terumasa Nakatsuka, Jianguo G.Gu)

Chapter 11 Opioid Receptors (Zhizhong Z.Pan)

Chapter 12 Retrograde Messengers (Min Zhuo)

Part Ⅳ Inhibitory Transmission and Plasticity

Chapter 13 Inhibitory Transmission (Tian-Le Xu）

Chapter 14 Plasticity of Inhibition; GABA/glycine Svstems (Yves De Koninck)

Part Ⅴ Postsynaptic Signaling and Gene Regulation

Chapter 15 Protein Kinases and Phosphatases(Ronald A. Merrill, Stefan Strack）

Chapter 16 Activity-dependent Gene Regulation:How Do Synapses Talk to the Nucleus and Fine-tune Neuronal Outputs? (Haruhiko Bito, Sayaka Takemoto-Kimura,Hiroyuki Okunc)

Chapter 17 Second Messenger Pathways in Pain (Kathleen A.Sluka, David A.Skyba, Marie K.Hoeger Bement, Katherine M. Audette,Rajan Radhakrishnan )

Chapter 18 Genetic Approaches for the Study of Pam（Rohini Kuner)

Part Ⅵ Peripheral Nociceptor, Amygdala and Fear

Chapter 19 Peripheral Nociceptors (Makoto Tominaga)

Cbapter 20 Amygdala—Pain Processing and Pain Modulation (Volker Neugebauer)

Chapter 2l Fear Learning (Paul W.Frankland Sheena A.Josselyn)

Part Ⅶ Spinal Plasticity, Reorganization and Chronic Pain

Chapter 22 Silent Glutamatergic Synapses and Long-term Facilitation in Spinal Dorsal Horn Neurons (Min Zhuo)

Chapter 23 Anatomical Changes in the Spinal Dorsal Horn after Peripheral Nerve Injury(Andrew J.Todd, Alfredo Ribeiro-da-Silva)

Chapter 24 Spinal Microglia in Neuropathic Pain Plasticity (MichaelWSalter )

Part Ⅷ Cortical Plasticity, Reorganization and Amputation

Chapter 25 ACC Plasticity (Min Zhuo)

Chapter 26 Reorganization of the Sensorimotor System after Injury(Huixin Qi,Jon H.Kaas)

Part Ⅸ Endogenous Analgesia and Other Form of Analgesia

Chapter 27 Endogenous Biphasic Modulation (Min Zhuo,Gerald F.Gebhart)

Chapter 28 Paradoxical Analgesic and Hyperalgesic Effects of Stress (Meredith Tumbach Robbins Timothy J.Ness)

Chapter 29 Acupuncture Analgesia (Zhi-Qi Zhao)

Chapter 30 Mechanisms of Opioid Tolerance (Zhizhong Z.Pan)

Part Ⅹ Models for Studying Pain and Searching for Pain Killers

Chapter 31 Models in Pain Research (Timothy J.Ness)

Chapter 32 Models for Studying Pain and Searching for Pain Killers in Intro Electrophysiological Studies of Pain(Peter Goldstein, Jianguo Gu)

Chapter 33 Whole-cell Patch-clamp Recording in rivo (Megumu Yoshimura)

Chapter 34 Basic Mechanisms of Clinically Used Drugs(Annika B. Malmberg)

Selected References

Appendix Ⅰ Units in Pain Research

Appendix Ⅱ Useful Websites for the Study of Pain

Appendix Ⅲ List of Scientific Journals Publishing Studies in Pain

Appendix Ⅳ Fundamental and Innovative Contribution to Understanding of Basic Mechanism of Pain, Analgesia and Persistent Pain

Chapter 34 Basic Mechanisms of Clinically Used Drugs(Annika B. Malmberg)

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