|
|
Effects of aflatoxin-detoxifizyme on growth performance and liver biochemical indices of broilers fed with aflatoxin B1 |
Baojiang CHEN1( ), Yong WANG1, Huimin YU2, Qing XU1 |
1. College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071000, China; 2. Feed Research Institute, Chinese Academy of Agricultural Science, Beijing 100086, China |
|
|
Abstract Aflatoxin-detoxifizyme (ADTZ) was evaluated for its ability to reduce the deleterious effects of aflatoxin B1 (AFB1) in broiler diets. A total of 624 one-day-old AA broilers were randomly divided into 3 treatment groups with 8 replicates each. The control, AFB1 and ADTZ treatments were fed with basal diet, basal diet+ 0.1 mg/kg AFB1 and basal diet+ 0.1 mg/kg AFB1 + 0.3% ADTZ, respectively. The trials lasted 42 days. The results showed that: (1) AFB1 diminished the growth performance of broilers significantly (P<0.01). (2) The AFB1 supplement caused significant alteration of related liver enzyme activities and significantly decreased the body’s antioxidant capacity. (3) Related parameters were returned to normal levels by a 0.3% ADTZ addition to the AFB1-contaminated diet. All the results in the trials indicate that ADTZ has the ability to detoxify AFB1 and recover the negative effects of AFB1.
|
Keywords
aflatoxin-detoxifizyme (ADTZ)
aflatoxin B1(AFB1)
broilers
growth performance
liver biochemical indices
|
Corresponding Author(s):
CHEN Baojiang,Email:chenbaojiang@sina.vip.com
|
Issue Date: 05 December 2011
|
|
1 |
Chen F, Lu Y H, Wang X H (2008). Study on non-selectional adsorption of vitamins by mycotoxin adsorbent. Chinese Journal of Animal Science , 44(18): 8–10 (in Chinese)
|
2 |
Hou R R, Xie P, Zhang M H, Feng J H, Zheng S S, Ma A P (2008b). Effects of glucomannan on liver biochemical indices and hepatic pathological observation of broilers fed with dietary containing aflatoxin B1. Chinese Journal of Animal Nutrition , 20(2): 152–157 (in Chinese)
|
3 |
Hou R R, Zheng S S, Zhang M H, Feng J H, Ma A P, Xie P (2008a). Effects of glucomannan on growth performance, serum and organ indices of broilers fed with dietary containing aflatoxin B1. Chinese Journal of Animal Nutrition , 20(2): 146–151 (in chinese)
|
4 |
Richard L (1989). Microbial toxins in foods and feeds. Symposium on Cellular and Molecular Mode of Action of Selected Microbial Toxins in Foods and Feeds . New York: Plenum Press, 1990
|
5 |
Lindemann M D, Blodgett D J, Kornegay E T, Schurig G G (1993). Potential ameliorators of aflatoxicosis in weanling/growing swine. J Anim Sci , 71(1): 171–178 pmid:8384193
|
6 |
Long X K, Tang R G, Hang H Q (2007). Analysis of detection level of serum lipid and cholinesterase in patients with liver cancer. Journal of Practical Medical Techiques , 14(12): 1574–1575 (in Chinese)
|
7 |
Quezada T, Cuellar H, Jaramillo-Juarez F, Valdivia A G, Reyes J L (2000). Effect of aflatoxin B1 on the liver and kidney of broiler chickens during development. Comp Biochem Physiol , 125(Part C): 265–272
|
8 |
Shi Y H, Xu Z R, Wang C Z (2007). Effects of aflatoxin on growth performance and immunology and antioxidant indices in pigs. Chin J Vet Sci , 27(5): 733–736 (in Chinese)
|
9 |
Verma J, Swain B K, Johri T S (2002). Effect of various levels of aflatoxin and ochratoxin A and combinations thereof on protein and energy utilisation in broilers. J Sci Food Agric , 82(12): 1412–1417
|
10 |
Wills E D (1966). Mechanism of lipid peroxide formation in animal tissues. J Biochem , 99: 667–676
|
11 |
Wilson R W, Bergman H L, Wood C M (1994). Metabolic costs and physiological consequences of acclimation to aluminum in juvenile rainbow trout (Oncorhynchus mykiss). II. Gill morphology, swimming performance, and aerobic scope. Can J Fish Aquat Sci , 51: 536–544
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|