Genomic regions under selection for important traits in domestic horse breeds

doi:10.15302/J-FASE-2017155

Front. Agr. Sci. Eng.

2017, Vol. 4

Issue (3) : 289-294 https://doi.org/10.15302/J-FASE-2017155

REVIEW

Genomic regions under selection for important traits in domestic horse breeds

Xuexue LIU^1,², Yuehui MA^1,², Lin JIANG^1,²(

)

¹. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
². CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China

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Abstract

Horses were domesticated 5500 years ago, thousands of years later than other domestic animals; however, in this relatively short period, domestic horses have had a great impact on human history by accelerating civilization, revolutionizing warfare and advancing agricultural production. Modern breeding using marker-assisted selection has greatly accelerated breeding progress. Therefore, identification of genetic markers underlying the traits of interest in domestic horses is the basis for the modern breeding system. In this review, we present an overview of genetic mapping studies and genome wide analyses to identify the genomic regions targeted by positive selection for four important aspects of horses, coat color, racing performance, gait and height at withers. The MC1R locus, for example, has been shown to be the main gene responsible for chestnut color, and the MSTN locus has been shown to control the muscle fiber growth in racing breeds. The missense mutation in DMRT3 is the causal mutation for the alternate gaits in horses. Height at withers, a quantitative trait, was mapped to four major loci (3:105547002, 6:81481064, 9:75550059 and 11:232597 32) that can explain 83% of the height variations in domestic horses.

Keywords horse coat color racing performance gait height

Corresponding Author(s): Lin JIANG

Just Accepted Date: 07 April 2017 Online First Date: 26 April 2017 Issue Date: 12 September 2017

Cite this article:

Xuexue LIU,Yuehui MA,Lin JIANG. Genomic regions under selection for important traits in domestic horse breeds[J]. Front. Agr. Sci. Eng. , 2017, 4(3): 289-294.

URL:

https://academic.hep.com.cn/fase/EN/10.15302/J-FASE-2017155
https://academic.hep.com.cn/fase/EN/Y2017/V4/I3/289

Tab.1 Causative mutations for coat coloration in domestic horses

Tab.2 Causative mutations for the height at withers in domestic horses

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