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Frontiers of Chemistry in China

ISSN 1673-3495

ISSN 1673-3614(Online)

CN 11-5726/O6

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Front. Chem. China    2008, Vol. 3 Issue (3) : 353-358    https://doi.org/10.1007/s11458-008-0055-7
Electrochemical behaviors of ofloxacin and its voltammetric determination at carbon nanotubes film modified electrode
YANG Chunhai1, ZHANG Shenghui2, LIU Yingxuan2, HUANG Wensheng2
1.Key Laboratory of Biological Resources Protection and Utilization of Hubei Province; Department of Chemistry, Hubei Institute for Nationalities; College of Chemistry and Molecular Sciences, Wuhan University; 2.Key Laboratory of Biological Resources Protection and Utilization of Hubei Province; Department of Chemistry, Hubei Institute for Nationalities
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Abstract A multi-wall carbon nanotubes (MWNTs)-Nafion film-coated glassy carbon electrode (GCE) was fabricated and the electrochemical behavior of ofloxacin on the MWNTs-Nafion film-coated GCE were investigated by cyclic voltammetry (CV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS). The oxidation peak current of ofloxacin increased significantly on the MWNTs-Nafion film modified GCE compared with that using a bare GCE. This nano-structured film electrode exhibited excellent enhancement effects on the electrochemical oxidation of ofloxacin. A well-defined oxidation peak attributed to ofloxacin was observed at 0.97 V and was applied to the determination of ofloxacin. The oxidation peak current was proportional to ofloxacin concentration in the ranges 1.0 × 10-8 to 1.0 × 10-6 mol/L and 1.0 × 10-6 to 2.0 × 10-5 mol/L. A detection limit of 8.0 × 10-9 mol/L was obtained for 400 s accumulation at open circuit (S/N = 3). This method for the detection of ofloxacin in human urine was satisfactory.
Issue Date: 05 September 2008
 Cite this article:   
ZHANG Shenghui,YANG Chunhai,LIU Yingxuan, et al. Electrochemical behaviors of ofloxacin and its voltammetric determination at carbon nanotubes film modified electrode[J]. Front. Chem. China, 2008, 3(3): 353-358.
 URL:  
https://academic.hep.com.cn/fcc/EN/10.1007/s11458-008-0055-7
https://academic.hep.com.cn/fcc/EN/Y2008/V3/I3/353
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