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Synthesis and fungicidal activity of novel 3,5-diarylpyrazole
derivatives |
| LIU Xinhua1, ZHU Jing1, PAN Chunxiu1, LI Bo1, SONG Bao‘an2 |
| 1.School of Chemistry and Chemical Engineering, Anhui University of Technology; 2.Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Education |
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Abstract (E)-3-(2-chlorophenyl)-1-(2,4-dichlorophenyl)prop-2-en-1-one was prepared from 2-chlorobenzaldehyde followed by cyclization with hydrazine monohydrate. Eight new 3-(2,4-Di-chlorophenyl)-5-(2-chlorophenyl)-4,5- dihydro-N-acylpyrazole derivatives were synthesized and characterized by elemental analysis, IR and 1H NMR spectroscopy. The experimental results show that the inhibition ratio of compounds 3f towards H. Oryzae and P. oryzae at 50 mg·L-1 is 55.2% and 57.1%, respectively. The inhibition ratio of compounds 3g towards H. Oryzae, P. oryza, S. Sclerotiorum at 50 mg·L-1 is 53.3%, 60.0%, 50.4% respectively.
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Issue Date: 05 December 2008
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