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Fluorescent molecular probes for the detection
of chemical warfare agents and their mimics |
Yanchun BAI,Chao ZHANG,Chunhu XU,Chunhua YAN, |
Beijing National Laboratory
for Molecular Sciences, State Key Lab of Rare Earth, Materials Chemistry
and Applications and PKU-HKU Joint Lab in Rare Earth Materials and
Bioinorganic Chemistry, Peking University, Beijing 100871, China; |
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Abstract Owing to their direct toxic effects on human beings, animals, and plants, chemical warfare agents (CWAs) and their mimics have become widespread in chemical warfare and agriculture. The considerable concerns about their entry into biological systems and the residues in environment stimulate the development of rapid and sensitive methods for the detection and analysis of this family of compounds. In the progress of sensitive, selective, and fast responsive detection, fluorescent molecular probes have been widely used in the detection of CWAs in recent years. Here the recent reports on the design of fluorescent molecular probes and their advantages in the detection of CWAs were reviewed. Furthermore, the extensive interests accelerate the development of novel fluorescent molecular probes and detection techniques in this field.
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Keywords
chemical warfare agents
detection
fluorescent
molecular probes
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Issue Date: 05 June 2010
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