The positive effects of Mediterranean-neutropenic diet on nutritional status of acute myeloid leukemia patients under chemotherapy

doi:10.1007/s11515-018-1519-x

Front. Biol.

2018, Vol. 13

Issue (6) : 475-480 https://doi.org/10.1007/s11515-018-1519-x

RESEARCH ARTICLE

The positive effects of Mediterranean-neutropenic diet on nutritional status of acute myeloid leukemia patients under chemotherapy

Jalali, Seyyed Mostafa, Morteza Abdollahi(

), Atiyeh Hosseini, Dehghani Kari Bozorg, Ajami, Marjan Azadeh, Kimia Moiniafshar

7th Floor, Bldg No.2 SBUMS, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Tehran 19839-63113, Iran

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Abstract

INTRODUCTION: Cancer and chemotherapy-induced malnutrition increase death, reduce the response to treatment, and increase multiple kinds of side effects. The aim of this study was to investigate the effects of Mediterranean-neutropenic diet on the nutritional status of acute myeloid leukemia patients under chemotherapy.

MATERIALS AND METHODS: 50 patients were divided into two groups by a random allocation scheme: the Mediterranean-neutropenic diet (n = 25) and the neutropenic diet group (n = 25). The intervention was implemented during a one month period. The nutritional status was evaluated based on PG-SGA. Serum albumin levels and dietary intake were also measured.

RESULTS: After the intervention, the mean serum albumin level in the intervention group was significantly higher than the beginning of the study (p = 0.09) and in comparison with the control group (p = 0.01). Also, the mean serum albumin level in the control group significantly decreased at the end of the study compared to the beginning of the study (p = 0.03). After intervention, the nutritional status of the patients in the intervention group was significantly improved compared to the control group.

CONCLUSION: In general, based on the results of this study, the Mediterranean neutropenic diet improves nutritional status during chemotherapy by increasing food intake, preventing weight loss and increasing serum albumin levels

Keywords nutritional status Mediterranean diet neutropenic diet AML chemotherapy

Corresponding Author(s): Morteza Abdollahi

Online First Date: 07 November 2018 Issue Date: 30 November 2018

Cite this article:

Jalali,Seyyed Mostafa,Morteza Abdollahi, et al. The positive effects of Mediterranean-neutropenic diet on nutritional status of acute myeloid leukemia patients under chemotherapy[J]. Front. Biol., 2018, 13(6): 475-480.

URL:

https://academic.hep.com.cn/fib/EN/10.1007/s11515-018-1519-x
https://academic.hep.com.cn/fib/EN/Y2018/V13/I6/475

Tab.1 participant's basic information in intervention and control group before and after intervention

Tab.2 serum albumin level before and after intervention

Tab.3 participant's calorie and macronutrients intake

Tab.4 bodyweight, BMI before and after intervention

Tab.5 nutritional status before and after intervention

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