It is of great necessity to observe Lu Xun from the human-geographical or cultural geographical perspective. Even the couple of corresponding case studies are able to reveal the whole picture. The “memes” of Lu Xun existed in the tie of Lu Xun with Shaanxi province, in the existential and imaginary relationships between him and the two cities of “An” (Xi’an and Yan’an), in Lu Xun studies conducted by Shaanxi’s academic community, and in a variety of cultural events and phenomena such as Shaanxi writers’ publications, as well as conferences and calligraphy activities in Shaanxi, are hinting from the indirect aspects at the profound impacts of Lu Xun over the modern and contemporary culture in China. The transmission, reception and transformation of Lu Xun in Shaanxi during various historical stages also indicate the changes occurring to political ideology, aesthetic judgment, values and academic paradigms. To discuss Lu Xun’s “memes” in the regional culture of Shaanxi, which closely combines the region in the physical sense of cultural geography and Lu Xun study, is an important component of Lu Xun studies, as well as an effective path to delve into the research on the ties of Lu Xun with China, or even with the world, for the further attempt to comprehensively understand the significance and value of Lu Xun to the new culture in China, as well as to the modern and contemporary culture.