Effect of Feixian Recipe on laminin, collagen
I and III in rats with pulmonary fibrosis induced by bleomycin
Effect of Feixian Recipe on laminin, collagen
I and III in rats with pulmonary fibrosis induced by bleomycin
ZHANG Xiaomei1, JIANG Liangduo2, ZHANG Wei2, WU Jianjun3, LU Xiangfeng4
1.Department of Respiratory Diseases, Dongfang Hospital, Beijing University of Chinese Medicine; 2.Department of Internal Medicine, Dongzhimen Hospital, Beijing University of Chinese Medicine; 3.Department of Traditional Chinese Medicine, Beijing Royal Integrative Medicine Hospital; 4.Department of Pathology, Dongzhimen Hospital, Beijing University of Chinese Medicine
Abstract：The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats. A rat model with pulmonary fibrosis was established by intratracheal injection of bleomycin. On days 14, 28 and 45, the contents of laminin, collagen I and collagen III in lung tissue homogenate in the model group, the sham operated group, the Feixian group and the prednisone group were measured. The contents of laminin and collagen I and III were decreased significantly by the Feixian Recipe. Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.
出版日期: 2008-09-05
引用本文:
. Effect of Feixian Recipe on laminin, collagen
I and III in rats with pulmonary fibrosis induced by bleomycin[J]. Frontiers of Medicine in China - Selected Publications from Chinese Universities, 2008, 2(3): 314-316.
ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng. Effect of Feixian Recipe on laminin, collagen
I and III in rats with pulmonary fibrosis induced by bleomycin. Front. Med., 2008, 2(3): 314-316.
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