Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance

doi:10.1007/s11684-007-0038-y

2007, Vol. 1

Issue (2) : 200-206 https://doi.org/10.1007/s11684-007-0038-y

Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance

XIA Yanzhi¹, WAN Xuedong², DUAN Qiuhong², HE Shansu², WANG Ximing²

1.Department of Medical Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 2.Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;

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Abstract Elevated plasma levels of free fatty acids (FFAs) may contribute to insulin resistance (IR) that is characteristic of type 2 diabetes mellitus. In this study, we investigated the effects of two fatty acids, palmitate (PA) and arach

Issue Date: 05 June 2007

Cite this article:

XIA Yanzhi,WAN Xuedong,DUAN Qiuhong, et al. Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance[J]. Front. Med., 2007, 1(2): 200-206.

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https://academic.hep.com.cn/fmd/EN/10.1007/s11684-007-0038-y
https://academic.hep.com.cn/fmd/EN/Y2007/V1/I2/200

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