|
|
|
Alcohol and tea consumption in relation to the
risk of nasopharyngeal carcinoma in Guangdong, China |
| Hong-Lian RUAN1,Feng-Hua XU1,Wen-Sheng LIU2,Qi-Sheng FENG2,Li-Zhen CHEN2,Yi-Xin ZENG2,Wei-Hua JIA3, |
| 1.State Key Laboratory
of Oncology in Southern China, Guangzhou 510060, China；School of Public Health,
Sun Yat-Sen University, Guangzhou 510080, China; 2.State Key Laboratory
of Oncology in Southern China, Guangzhou 510060, China；Department of Experiment
Research, Sun Yat-sen University, Cancer Center, Guangzhou 510060,
China; 3.State Key Laboratory
of Oncology in Southern China, Guangzhou 510060, China；School of Public Health,
Sun Yat-Sen University, Guangzhou 510080, China；Department of Experiment
Research, Sun Yat-sen University, Cancer Center, Guangzhou 510060,
China; |
|
|
|
|
Abstract To investigate whether alcohol and tea consumption has an etiological association with nasopharyngeal carcinoma (NPC) in a high-incident population, a large scale case-control study was conducted. The study included 2846 individuals in Guangdong Province, China, with 1387 newly diagnosed cases of NPC and 1459 frequency-matched controls. Exposure histories of alcohol and tea consumption were obtained via personal interviews. Information regarding socio-demographic characteristics (age, sex, education, dialect and household type), family history of NPC, Epstein-Barr virus (EBV) infection, dietary habits and other potential confounding factors was also studied. An analysis was performed using unconditional logistic regression to calculate odds ratios (OR) and 95% confidence intervals (CI). The risk of NPC was found to be associated with habitual alcohol consumption and tea consumption. Tea consumption has been associated with a decreased occurrence of NPC (OR= 0.62), while consumption of alcohol was associated with a complex effect. Specifically, moderate consumption of alcohol was associated with decreased risk of NPC, while overuse, especially strong distillate spirits, appeared to be a risk factor.
|
| Keywords
nasopharyngeal carcinoma
case-control study
alcohol consumption
tea consumption
|
|
Issue Date: 05 December 2010
|
|
|
Chang E T, Adami H O. The enigmatic epidemiology of nasopharyngeal carcinoma.Cancer Epidemiol Biomarkers Prev, 2006, 15(10): 1765–1777
PMID: 17035381
|
|
Chan A T C, Teo P M L, Johnson P J. Nasopharyngeal carcinoma.Ann Oncol, 2002, 13(7): 1007–1015
PMID: 12176778
|
|
Yu M C, Yuan J M. Epidemiology of nasopharyngeal carcinoma.Semin Cancer Biol, 2002, 12(6): 421–429
PMID: 12450728
|
|
Yu W M, Hussain S S. Incidence of nasopharyngeal carcinoma in Chinese immigrants, compared with Chinese in China and South East Asia: review.J Laryngol Otol, 2009, 123(10): 1067–1074
PMID: 19486543
|
|
Wei K R, Yu Y L, Yang Y Y, Ji M F, Yu B H, Liang Z H, Reng X. Epidemiological trends of nasopharyngeal carcinoma in China.Asian Pac J Cancer Prev, 2010, 11(1): 29–32
PMID: 20593926
|
|
Yu M C, Ho J H, Ross R K, Henderson B E. Nasopharyngeal carcinoma in Chinese---salted fish or inhaled smoke?Prev Med, 1981, 10(1): 15–24
PMID: 7232343
|
|
Henle W, Henle G, Ho H C, Burtin P, Cachin Y, Clifford P, de Schryver A, de-Thé G, Diehl V, Klein G. Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasms, and control groups.J Natl Cancer Inst, 1970, 44(1): 225–231
PMID: 11515035
|
|
Lin J C, Chen K Y, Wang W Y, Jan J S, Liang W M, Tsai C S, Wei Y H. Detection of Epstein-Barr virus DNA in the peripheral-blood cells of patientswith nasopharyngeal carcinoma: relationship to distant metastasisand survival.J Clin Oncol, 2001, 19(10): 2607–2615
PMID: 11352952
|
|
Lin J C, Wang W Y, Chen K Y, Wei Y H, Liang W M, Jan J S, Jiang R S. Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngealcarcinoma.N Engl J Med, 2004, 350(24): 2461–2470
PMID: 15190138
|
|
Ko J Y, Sheen T S, Hsu M M, Lui L T. Familial clustering of nasopharyngeal carcinoma.Otolaryngol Head Neck Surg, 1998, 118(5): 736–737
PMID: 9591887
|
|
Albeck H, Bentzen J, Ockelmann H H, Nielsen N H, Bretlau P, Hansen H S. Familial clusters of nasopharyngealcarcinoma and salivary gland carcinomas in Greenland natives.Cancer, 1993, 72(1): 196–200
PMID: 8508406
|
|
Loh K S, Goh B C, Lu J, Hsieh W S, Tan L. Familial nasopharyngeal carcinoma ina cohort of 200 patients.Arch Otolaryngol Head Neck Surg, 2006, 132(1): 82–85
PMID: 16415435
|
|
Yu M C, Ho J H, Lai S H, Henderson B E. Cantonese-style salted fish as a cause of nasopharyngeal carcinoma:report of a case-control study in Hong Kong.Cancer Res, 1986, 46(2): 956–961
PMID: 3940655
|
|
Yuan J M, Wang X L, Xiang Y B, Gao Y T, Ross R K, Yu M C. Preserved foods in relation to risk of nasopharyngealcarcinoma in Shanghai, China.Int J Cancer, 2000, 85(3): 358–363
PMID: 10652427
|
|
Zou J, Sun Q, Akiba S, Yuan Y, Zha Y, Tao Z, Wei L, Sugahara T. A case-control study of nasopharyngeal carcinoma in the high background radiation areas of Yangjiang, China.J Radiat Res (Tokyo), 2000, 41(Suppl): 53–62
PMID: 11142212
|
|
Yuan B W. (Correlation between nasopharyngeal carcinoma and HLAin Sichuan). Zhonghua Zhong Liu Za Zhi, 1988, 10(4): 263–266 (in Chinese)
PMID: 3248481
|
|
Hildesheim A, Apple R J, Chen C J, Wang S S, Cheng Y J, Klitz W, Mack S J, Chen I H, Hsu M M, Yang C S, Brinton L A, Levine P H, Erlich H A. Association of HLA class I and II allelesand extended haplotypes with nasopharyngeal carcinoma in Taiwan.J Natl Cancer Inst, 2002, 94(23): 1780–1789
PMID: 12464650
|
|
Lu C C, Chen J C, Jin Y T, Yang H B, Chan S H, Tsai S T. Genetic susceptibility to nasopharyngeal carcinoma withinthe HLA-A locus in Taiwanese.Int J Cancer, 2003, 103(6): 745–751
PMID: 12516093
|
|
Yu M C, Mo C C, Chong W X, Yeh F S, Henderson B E. Preserved foods and nasopharyngealcarcinoma: a case-control study in Guangxi, China.Cancer Res, 1988, 48(7): 1954–1959
PMID: 3349469
|
|
Zheng Y M, Tuppin P, Hubert A, Jeannel D, Pan Y J, Zeng Y, de Thé G. Environmental and dietary risk factors for nasopharyngeal carcinoma:a case-control study in Zangwu County, Guangxi, China.Br J Cancer, 1994, 69(3): 508–514
PMID: 8123482
|
|
Yu M C, Huang T B, Henderson B E. Diet and nasopharyngeal carcinoma:a case-control study in Guangzhou, China.Int J Cancer, 1989, 43(6): 1077–1082
PMID: 2732001
|
|
Ning J P, Yu M C, Wang Q S, Henderson B E. Consumption of salted fish and other risk factors for nasopharyngealcarcinoma (NPC) in Tianjin, a low-risk regionfor NPC in the people's Republic of China.J Natl Cancer Inst, 1990, 82(4): 291–296
PMID: 2299678
|
|
Armstrong R W, Armstrong M J, Yu M C, Henderson B E. Salted fish and inhalants as risk factors for nasopharyngealcarcinoma in Malaysian Chinese.Cancer Res, 1983, 43(6): 2967–2970
PMID: 6850606
|
|
Armstrong R W, Eng A C. Salted fish and nasopharyngeal carcinoma in Malaysia.Soc Sci Med, 1983, 17(20): 1559–1567
PMID: 6635717
|
|
Armstrong R W, Imrey P B, Lye M S, Armstrong M J, Yu M C, Sani S. Nasopharyngeal carcinoma in Malaysian Chinese: saltedfish and other dietary exposures.Int J Cancer, 1998, 77(2): 228–235
PMID: 9650558
|
|
Lee H P, Gourley L, Duffy S W, Esteve J, Lee J, Day N E. Preserved foods and nasopharyngeal carcinoma:a case-control study among Singapore Chinese.Int J Cancer, 1994, 59(5): 585–590
PMID: 7960230
|
|
Chen C J, Liang K Y, Chang Y S, Wang Y F, Hsieh T, Hsu M M, Chen J Y, Liu M Y. Multiple risk factors of nasopharyngealcarcinoma: Epstein-Barr virus, malarial infection, cigarette smoking and familial tendency.Anticancer Res, 1990, 10(2B): 547–553
PMID: 2161639
|
|
Mabuchi K, Bross D S, Kessler I I. Cigarette smoking and nasopharyngealcarcinoma.Cancer, 1985, 55(12): 2874–2876
PMID: 3995493
|
|
Chow W H, McLaughlin J K, Hrubec Z, Nam J M, Blot W J. Tobacco use and nasopharyngeal carcinoma in a cohort of US veterans.Int J Cancer, 1993, 55(4): 538–540
PMID: 8406978
|
|
Lin T M, Chen K P, Lin C C, Hsu M M, Tu S M, Chiang T C, Jung P F, Hirayama T. Retrospective study on nasopharyngeal carcinoma.J Natl Cancer Inst, 1973, 51(5): 1403–1408
PMID: 4762926
|
|
Yu M C, Garabrant D H, Huang T B, Henderson B E. Occupational and other non-dietary risk factors for nasopharyngealcarcinoma in Guangzhou, China.Int J Cancer, 1990, 45(6): 1033–1039
PMID: 2351484
|
|
Lanier A, Bender T, Talbot M, Wilmeth S, Tschopp C, Henle W, Henle G, Ritter D, Terasaki P. Nasopharyngeal carcinoma in Alaskan Eskimos Indians, and Aleuts: a review of cases and study of Epstein-Barr virus, HLA, and environmental risk factors.Cancer, 1980, 46(9): 2100–2106
PMID: 6253051
|
|
Cheng Y J, Hildesheim A, Hsu M M, Chen I H, Brinton L A, Levine P H, Chen C J, Yang C S. Cigarette smoking, alcohol consumption and risk of nasopharyngealcarcinoma in Taiwan.Cancer Causes Control, 1999, 10(3): 201–207
PMID: 10454065
|
|
Nam J M, McLaughlin J K, Blot W J. Cigarette smoking, alcohol, and nasopharyngeal carcinoma: a case-control study among U.S. whites.J Natl Cancer Inst, 1992, 84(8): 619–622
PMID: 1556772
|
|
IARC Working Group onthe Evaluation of Carcinogenic Risks to Humans. Tobacco smoke and involuntary smoking.IARC Monogr Eval Carcinog Risks Hum, 2004, 83: 1–1438
PMID: 15285078
|
|
Duhayon S, Hoet P, Van Maele-Fabry G, Lison D. Carcinogenic potential of formaldehyde in occupationalsettings: a critical assessment and possible impact on occupationalexposure levels.Int Arch Occup EnvironHealth, 2008, 81(6): 695–710
PMID: 17955258
|
|
Hildesheim A, West S, DeVeyra E, De Guzman M F, Jurado A, Jones C, Imai J, Hinuma Y. Herbal medicine use, Epstein-Barr virus, and risk of nasopharyngeal carcinoma.Cancer Res, 1992, 52(11): 3048–3051
PMID: 1317256
|
|
Vaughan T L, Shapiro J A, Burt R D, Swanson G M, Berwick M, Lynch C F, Lyon J L. Nasopharyngeal cancer in a low-risk population: definingrisk factors by histological type.Cancer Epidemiol Biomarkers Prev, 1996, 5(8): 587–593
PMID: 8824359
|
|
Armstrong R W, Imrey P B, Lye M S, Armstrong M J, Yu M C, Sani S. Nasopharyngeal carcinoma in Malaysian Chinese: saltedfish and other dietary exposures.Int J Cancer, 1998, 77(2): 228–235
PMID: 9650558
|
|
Geser A, Charnay N, Day N E, de-The G, Ho H C. Environmental factors in the etiology of nasopharyngeal carcinoma: report on a case-controlstudy in Hong Kong.IARC Sci Publ, 1978, (20): 213–229
PMID: 730191
|
|
Sriamporn S, Vatanasapt V, Pisani P, Yongchaiyudha S, Rungpitarangsri V. Environmental risk factors for nasopharyngeal carcinoma: a case-controlstudy in northeastern Thailand.Cancer Epidemiol Biomarkers Prev, 1992, 1(5): 345–348
PMID: 1305465
|
|
Gu Q, Hu C, Chen Q, Xia Y, Feng J, Yang H. Prevention of chinese green tea on 3,4-benzopyrene-induced lung cancer and its mechanism in animal mode. Zhongguo Fei Ai Za Zhi, 2008, 11(4): 519–523 (in Chinese)
PMID: 20735961
|
|
Arts I C. A review of the epidemiological evidence on tea, flavonoids, and lung cancer.J Nutr, 2008, 138(8): 1561S–1566S
PMID: 18641207
|
|
Lee A H, Liang W, Hirayama F, Binns C W. Association between green tea consumption and lung cancer risk.J Prev Med Public Health, 2010, 43(4): 366–367
PMID: 20689363
|
|
Tang N, Wu Y, Zhou B, Wang B, Yu R. Green tea, black tea consumption and risk of lung cancer: a meta-analysis.Lung Cancer, 2009, 65(3): 274–283
PMID: 19128856
|
|
Ogunleye A A, Xue F, Michels K B. Green tea consumption and breast cancerrisk or recurrence: a meta-analysis.Breast Cancer Res Treat, 2010, 119(2): 477–484
PMID: 19437116
|
|
Dai Q, Shu X O, Li H, Yang G, Shrubsole M J, Cai H, Ji B, Wen W, Franke A, Gao Y T, Zheng W. Is green tea drinking associated with a later onset ofbreast cancer?Ann Epidemiol, 2010, 20(1): 74–81
PMID: 20006278
|
|
Boggs D A, Palmer J R, Stampfer M J, Spiegelman D, Adams-Campbell L L, Rosenberg L. Tea and coffee intake inrelation to risk of breast cancer in the Black Women's Health Study. Cancer Causes Control, 2010, 21(11): 1941–1948
doi: 10.1007/s10552-010-9622-6
|
|
Ganmaa D, Willett W C, Li T Y, Feskanich D, van Dam R M, Lopez-Garcia E, Hunter D J, Holmes M D. Coffee, tea, caffeine and risk of breastcancer: a 22-year follow-up.Int J Cancer, 2008, 122(9): 2071–2076
PMID: 18183588
|
|
Zhang M, Huang J, Xie X, Holman C D. Dietary intakes of mushrooms and green tea combine to reduce therisk of breast cancer in Chinese women.Int J Cancer, 2009, 124(6): 1404–1408
PMID: 19048616
|
|
Drinking coffee and tea doesn't raise breast cancer risk.Mayo Clin Womens Healthsource, 2008, 12(12): 3
PMID: 18985018
|
|
Shrubsole M J, Lu W, Chen Z, Shu X O, Zheng Y, Dai Q, Cai Q, Gu K, Ruan Z X, Gao Y T, Zheng W. Drinking green tea modestly reduces breast cancer risk.J Nutr, 2009, 139(2): 310–316
PMID: 19074205
|
|
Kumar N, Titus-Ernstoff L, Newcomb P A, Trentham-Dietz A, Anic G, Egan K M. Tea consumption and risk of breast cancer.Cancer Epidemiol Biomarkers Prev, 2009, 18(1): 341–345
PMID: 19124518
|
|
Sun C L, Yuan J M, Koh W P, Yu M C. Green tea, black tea and colorectal cancer risk:a meta-analysis of epidemiologic studies.Carcinogenesis, 2006, 27(7): 1301–1309
PMID: 16638787
|
|
Yang G, Shu X O, Li H, Chow W H, Ji B T, Zhang X, Gao Y T, Zheng W. Prospective cohort study of green tea consumption andcolorectal cancer risk in women.Cancer Epidemiol Biomarkers Prev, 2007, 16(6): 1219–1223
PMID: 17548688
|
|
Arab L, Il'yasova D. The epidemiology of tea consumption and colorectal cancer incidence.J Nutr, 2003, 133(10): 3310S–3318S
PMID: 14519831
|
|
Yuan J M, Gao Y T, Yang C S, Yu M C. Urinary biomarkers of tea polyphenols and risk of colorectal cancerin the Shanghai Cohort Study.Int J Cancer, 2007, 120(6): 1344–1350
PMID: 17149697
|
|
Kim J W, Amin A R, Shin D M. Chemoprevention of head and neck cancerwith green tea polyphenols.Cancer Prev Res (Phila), 2010, 3(8): 900–909
PMID: 20663981
|
|
Galeone C, Tavani A, Pelucchi C, Turati F, Winn D M, Levi F, Yu G P, Morgenstern H, Kelsey K, Dal Maso L, Purdue M P, McClean M, Talamini R, Hayes R B, Franceschi S, Schantz S, Zhang Z F, Ferro G, Chuang S C, Boffetta P, La Vecchia C, Hashibe M. Coffee and tea intake andrisk of head and neck cancer: pooled analysis in the internationalhead and neck cancer epidemiology consortium.Cancer Epidemiol Biomarkers Prev, 2010, 19(7): 1723–1736
PMID: 20570908
|
|
Zou C, Liu H, Feugang J M, Hao Z, Chow H H, Garcia F. Green tea compound in chemoprevention of cervical cancer.Int J Gynecol Cancer, 2010, 20(4): 617–624
PMID: 20686382
|
|
Singh M, Tyagi S, Bhui K, Prasad S, Shukla Y. Regulation of cell growththrough cell cycle arrest and apoptosis in HPV 16 positive human cervicalcancer cells by tea polyphenols.Invest New Drugs, 2010, 28(3): 216–224
PMID: 19271153
|
|
Hsu A, Bruno R S, Lohr C V, Taylor A W, Dashwood R H, Bray T M, Ho E. Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFkappaBpathway in the Noble rat model. J Nutr Biochem, 2010 Aug 27. [Epub ahead of print]
PMID: 20801632
|
|
Pandey M, Gupta S. Green tea and prostate cancer: from bench to clinic.Front Biosci (Elite Ed), 2009, 1: 13–25
PMID: 19482620
|
|
Khan N, Adhami V M, Mukhtar H. Review: green tea polyphenols in chemopreventionof prostate cancer: preclinical and clinical studies.Nutr Cancer, 2009, 61(6): 836–841
PMID: 20155624
|
|
Kurahashi N, Sasazuki S, Iwasaki M, Inoue M, Tsugane S, Green tea consumption and prostate cancer risk in Japanese men: aprospective study.Am J Epidemiol, 2008, 167(1): 71–77
PMID: 17906295
|
|
Siddiqui I A, Adhami V M, Saleem M, Mukhtar H. Beneficial effects of tea and its polyphenols against prostate cancer.Mol Nutr Food Res, 2006, 50(2): 130–143
PMID: 16425281
|
|
Lee A H, Fraser M L, Meng X, Binns C W. Protective effects of green tea against prostate cancer.Expert Rev Anticancer Ther, 2006, 6(4): 507–513
PMID: 16613539
|
|
Jia W H, Luo X Y, Feng B J, Ruan H L, Bei J X, Liu W S, Qin H D, Feng Q S, Chen L Z, Yao S Y, Zeng Y X. Traditional Cantonese diet and nasopharyngeal carcinomarisk: a large-scale case-control study in Guangdong, China.BMC Cancer, 2010, 10(1): 446
PMID: 20727127
|
|
Ung A, Chen C J, Levine P H, Cheng Y J, Brinton L A, Chen I H, Goldstein A M, Hsu M M, Chhabra S K, Chen J Y, Apple R J, Yang C S, Hildesheim A. Familial and sporadic cases of nasopharyngeal carcinoma in Taiwan.Anticancer Res, 1999, 19(1B): 661–665
PMID: 10216473
|
|
Zheng X, Yan L, Nilsson B, Eklund G, Drettner B. Epstein-Barr virus infection,salted fish and nasopharyngeal carcinoma. A case-control study insouthern China.Acta Oncol, 1994, 33(8): 867–872
PMID: 7818917
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
