Multifunctional nanoparticle systems for combined chemo- and photothermal cancer therapy
Multifunctional nanoparticle systems for combined chemo- and photothermal cancer therapy
Hai WANG1, Yu-Liang ZHAO1,2(), Guang-Jun NIE1()
1. CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology (NCNST), 11 Beiyitiao, Zhongguancun, Beijing 100190, China; 2. CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China
Hyperthermia has long been considered as an adjuvant therapy for treating various diseases. Cancer treatment exploiting hyperthermia shows great clinical potential for a wide range of tumors. Importantly, the efficacy of hyperthermal therapy has recently been enhanced by the development of functional nanomaterials. The unique physicochemical properties of nanomaterials afford the specific localization of hyperthermia to primary tumors and early-stage cancers. In particular, due to their high rate of light-to-heat conversion and their capacity to be activated by tissue-penetrating electromagnetic radiation, near-infrared (NIR) light-absorbing plasmonic nanomaterials have attracted considerable attention as candidates for noninvasive photothermal therapy. The purpose of this article is to provide a overview on the current development in multifunctional nanomaterials capable of combined hyperthermia-chemotherapy delivery.
Corresponding Author(s):
ZHAO Yu-Liang,Email:zhaoyuliang@ihep.ac.cn (Y.L.Z.); NIE Guang-Jun,Email:niegj@nanoctr.cn (G.J.N.)
引用本文:
. Multifunctional nanoparticle systems for combined chemo- and photothermal cancer therapy[J]. Frontiers of Materials Science, 2013, 7(2): 118-128.
Hai WANG, Yu-Liang ZHAO, Guang-Jun NIE. Multifunctional nanoparticle systems for combined chemo- and photothermal cancer therapy. Front Mater Sci, 2013, 7(2): 118-128.
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