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Frontiers of Materials Science

ISSN 2095-025X

ISSN 2095-0268(Online)

CN 11-5985/TB

Postal Subscription Code 80-974

2018 Impact Factor: 1.701

Front. Mater. Sci.    2008, Vol. 2 Issue (2) : 214-220    https://doi.org/10.1007/s11706-008-0036-2
Preparation and antibacterial activity of chitosan microshperes in a solid dispersing system
KONG Ming1, CHEN Xi-guang2, LIU Cheng-sheng2, YU Le-jun2, JI Qiu-xia2, XUE Yu-ping3, CHA Dong Su4, PARK Hyun Jin4
1.College of Marine Life Science, Ocean University of China;The Graduate School of Biotechnology, Korea University; 2.College of Marine Life Science, Ocean University of China; 3.Qingdao Technical College; 4.The Graduate School of Biotechnology, Korea University
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Abstract In this study, we investigated the interface contacting inhibition behaviors of chitosan against bacterial in the dispersing state. For that purpose, chitosan microspheres (CMs) in the dispersing state was prepared by the emulsification cross-linking method. The CMs had smooth surface and spherical shape with the diameter of about 124 ?m. They were stable after sterilization at 121°C and 150 kPa for 20 min. The CMs had similar antibacterial activity to that of chitosan in the solution form. Their antibacterial activities increased with the increase of the CM concentration, while decreased with the increase of pH of the system. It was found that the CMs with the degree of deacetylation (DD) of 63.6% exhibited the highest antibacterial activity, while the CMs with the DD of 83.7% exerted the lowest antibacterial activity among the three tested samples.
Issue Date: 05 June 2008
 Cite this article:   
CHEN Xi-guang,KONG Ming,CHA Dong Su, et al. Preparation and antibacterial activity of chitosan microshperes in a solid dispersing system[J]. Front. Mater. Sci., 2008, 2(2): 214-220.
 URL:  
https://academic.hep.com.cn/foms/EN/10.1007/s11706-008-0036-2
https://academic.hep.com.cn/foms/EN/Y2008/V2/I2/214
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