Fundamental studies on enhancement and blinking mechanism of surface-enhanced Raman scattering (SERS) and basic applications of SERS biological sensing
Fundamental studies on enhancement and blinking mechanism of surface-enhanced Raman scattering (SERS) and basic applications of SERS biological sensing
Yuko S. Yamamoto1, Mitsuru Ishikawa2, Yukihiro Ozaki3, Tamitake Itoh1()
1. Nano-Bioanalysis Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan; 2. Department of Chemistry, Josai University, Itado, Saitama 350-0295, Japan; 3. Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo 669-1337, Japan
We review recent our results in the fundamental study of surface-enhanced Raman scattering (SERS) with emphasis on experiments that attempted to identify the enhancement and blinking mechanism using single Ag nanoparticle dimers attached to dye molecules. These results are quantitatively discussed in the framework of electromagnetic mechanism. We also review recent our results in basic SERS applications for biological sensing regarding detections of cell surface molecules and distinction of disease marker molecules under single cell and single molecule level.
. Fundamental studies on enhancement and blinking mechanism of surface-enhanced Raman scattering (SERS) and basic applications of SERS biological sensing[J]. Frontiers of Physics, 2014, 9(1): 31-46.
Yuko S. Yamamoto, Mitsuru Ishikawa, Yukihiro Ozaki, Tamitake Itoh. Fundamental studies on enhancement and blinking mechanism of surface-enhanced Raman scattering (SERS) and basic applications of SERS biological sensing. Front. Phys. , 2014, 9(1): 31-46.
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