As a significant exposition, promoting the “two adaptions” of the basic tenets of Marxism holistically relates to the essence of Marxism. In the realistic dimension, adapting the basic tenets of Marxism to China’s specific realities is essentially to enable Marxism to blossom and bear fruits in China, which include seeking a right path for China to solve the principal contradiction facing Chinese society and the fundamental issues and advance its development and progress, as well as pursuing innovation of Marxism. In the historical dimension, adapting the basic tenets of Marxism to China’s fine traditional culture is essentially to help Marxism take root in China, and to use Marxist standpoints, viewpoints, and methods to transform and develop traditional Chinese culture in a creative and innovative manner. In the theoretical dimension, the “two adaptions,” which are fundamental to pursuing innovation of Marxism, have created Marxism adapted to the Chinese context. To advance the “two adaptions,” it is necessary to systematically and thoroughly sum up and adhere to the experience of “two adaptions,” draw the essence of China’s fine traditional culture, combine “advantage combination” with “functional complementation,” and grasp the connotation of China’s specific realities from the perspective of “historical juncture,” “principal social contradiction,” “fundamental issues” and “Chinese path.”