This study selects the science and technology-themed papers between 2000 and 2020 from five high-quality philosophical journals within the China National Knowledge Infrastructure (CNKI) database. Through the quantitative and visual processing of CiteSpace and the analysis of literature content, it is found that since the 21st century, the philosophical study of science and technology has made comprehensive advancements in science, technology and humanities, science, technology and nature, science, technology and society, and the theoretical interpretation and discipline construction of the philosophy of science and technology. Moreover, these advancements have given rise to a distinctive Chinese research paradigm, forging unique trajectories of the discipline and fostering collaborative research groups. The philosophical study of science and technology is firmly rooted in the fabric of real-life experience intricately linked to the national context. It has gone through the transformation from theoretical research to practical exploration, and holds both theoretical and practical value. Meanwhile, the conceptual boundaries of science and technology have branched into various fields, including information philosophy, industry philosophy, and biological philosophy, signifying a more profound, concrete, extensive, and farreaching exploration of the subject.