Artificial intelligence (AI) is a revolutionary and overwhelming technology that is yet to immature. While profoundly changing and shaping people and society, AI also splits into its own opposites and develops into a new external alien force. As the basic technical support of the entire society, intelligent technology entails the overt or covert domination of human beings, who are becoming the “vassals” and “slaves” of this high-speed intelligent social system. Various intelligent systems are constantly replacing human work, so that the “digital poor” gradually lose the opportunities and values offered by labor and hence are excluded by the global economic and social system, rendering their existence empty and absurd. The rapid development of intelligent robots has blurred the boundary between humans and machines and had a strong impact on the nature of man and his position as a conscious agent, making “What is man?” and the human-machine relationship prominent issues for our times, challenging the commonplaces of philosophy. We must face up to the existing or imminent risk of alienation, expand our theoretical horizons, innovate theories of alienation in the era of intelligence, take constructive action in terms of the construction of an ideal society and the evolution of man himself, build an ecological system for the joint evolution and growth of human beings and intelligent machines, and achieve liberty of man and the all-round and free development.