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The effects of hypoxia on major blood components: a brief review |
| Ming Li1,3, Yang Li1,2, Changhong Ren1, Hong An1,3,4, Fang Jiang4, Feng Yan4, Sijie Li1, Di Wu3, Changqing Xia2, Xunming Ji1,3,4 |
| 1. Beijing Key Laboratory of Hypoxia Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University,Beijing 100053, China
2. Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
3. China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
4. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China |
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Abstract The prevalence of stroke displays obvious geographical variation and is higher on plateaus.Similarly, prolonged stay at high altitude is associated with higher incidence of stroke. High-altitude hypoxia can elicit various physiological dysfunctions, and hypoxia is suggested to be the principal contributing factor of stroke. In this brief review, the effects of hypoxia on the properties of the blood components such as erythrocytes, leukocytes and thrombocytes are presented, in an effort to inform the prevention and treatment of stroke in high-altitude areas.
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| Keywords
hypoxia
cerebral blood
stroke
high altitude
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Issue Date: 15 October 2017
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| Cite this article: |
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Ming Li, Yang Li, Changhong Ren, Hong An, Fang Jiang, Feng Yan, Sijie Li, Di Wu, Changqing Xia, Xunming Ji . The effects of hypoxia on major blood components: a brief review[J]. Journal of Translational Neuroscience,2017, 2(2): 31-36.
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| URL: |
https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2017.02.005
https://academic.hep.com.cn/jtn/EN/Y2017/V2/I2/31
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