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Journal of Translational Neuroscience(转化神经科学电子杂志)

ISSN 2096-0689

CN 11-9363/R

Journal of Translational Neuroscience    2020, Vol. 5 Issue (2) : 34-39    https://doi.org/10.3868/j.issn.2096-0689.2020.02.004
Research Article
Effect of improving prehospital hypotension and hypoxemia on the prognosis of patients with traumatic brain injury
Liang Liang1*, Liwei Wu1, Yaowen Hu1, Xin Li1, Haiqing Dong1, Xiaofeng Sun2
1.Department of Neurosurgery, the First Central Hospital of Baoding, Baoding 071000, China
2.Department of Neurosurgery, the Second Hospital of Hebei Medical University, Shijiazhuang 050051, China
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Abstract Objective: to investigate the effect of improving prehospital hypotension and hypoxemia on the prognosis of different subgroups of patients with traumatic brain injury (TBI). Methods: medical staff were trained about the prehospital first aid for 2 months to fully master the methods of improving prehospital hypotension and hypoxemia, then the prognosis of TBI patients pre- and post-training for 12 months was collected and recorded. The prognostic differences of different TBI subgroups were discussed through data analysis. Results: after the training, the proportion of prehospital hypotension and hypoxemia in TBI patients decreased by 77% (8.5% vs. 1.9%) and 63% (9.9% vs. 3.6%, P < 0.05), respectively. However, only the prognosis of moderate and severe TBI patients was improved, the proportion of patients with “good prognosis” increased by 14% (61.4% vs. 70.5%, respectively) and 62% (35.6% vs. 58%), and no significant effect showed in mild and critical TBI patients.Conclusion: reducing the incidence of prehospital hypoxemia and hypotension can improve the prognosis of moderate and severe TBI patients, while no significant effect on mild and critical TBI patients.
Keywords traumatic brain injury (TBI)      prehospital hypotension and hypoxemia      Glasgow outcome scale (GOS)      management guide     
Issue Date: 25 June 2020
 Cite this article:   
Liang Liang, Liwei Wu, Yaowen Hu, Xin Li, Haiqing Dong, Xiaofeng Sun. Effect of improving prehospital hypotension and hypoxemia on the prognosis of patients with traumatic brain injury[J]. Journal of Translational Neuroscience,2020, 5(2): 34-39.
 URL:  
https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2020.02.004
https://academic.hep.com.cn/jtn/EN/Y2020/V5/I2/34
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