Clinical observation of Shenling Baizhu Powder combined with triamcinolone acetonide in treating macular edema induced by retinal vein occlusion

doi:10.3868/j.issn.2096-0689.2021.03.005

2021, Vol. 6

Issue (3) : 30-36 https://doi.org/10.3868/j.issn.2096-0689.2021.03.005

Clinical observation of Shenling Baizhu Powder combined with triamcinolone acetonide in treating macular edema induced by retinal vein occlusion

Zhiqiang Wang¹, Muchen Luo¹, Ziyang Huang²,Wanyu Zhou^*

1.Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing 100029, China
2.Department of Ophthalmology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China

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Abstract Objective: to observe the clinical efficacy of Shenling Baizhu Powder (SLBZP) combined with a subconjunctival injection of triamcinolone acetonide (TA) in treating macular edema (ME) induced by retinal vein occlusion (RVO). Methods: there were 62 patients (62 eyes) with ME induced by RVO that were selected and divided into two groups in accordance with the random number table. Each group had 31 eyes. Group one, the control group, was treated with a single subconjunctival injection of TA; group two, the observation group, was treated with a single subconjunctival injection of TA (20mg/0.5mL) per eye and one month of SLBZP. To evaluate the clinical efficacy, both groups were checked (3×) with the best corrected-visual acuity (BCVA), center macular thickness (CMT), and intraocular pressure (IOP). The checks were before treatment, one month after injection, and three months after injection. Results: there were 26 eyes (83.87％) in the observation group, and 17 eyes (54.84%) in the control group in which the BCVA was significantly improved. The ME obviously decreased in 27 eyes (87.10%) the observation group and in 19 eyes (61.29%) the control group. The clinical efficacy of the observation group was significantly better than that of the control group (P<0.05). Conclusion: as one method to treat ME induced by RVO, SLBZP combined with subconjunctival injection of TA is significantly more effective than a single subconjunctival injection of TA.Besides, the SLBZP had less side-effects. Based on the above, this method deserves in-depth research.

Keywords Shenling Baizhu Powder (SLBZP) tiamcinolone acetonide (TA) retinal vein occlusion (RVO) macular edema (ME) injection

Issue Date: 25 September 2021

Cite this article:

Zhiqiang Wang, Muchen Luo, Ziyang Huang,Wanyu Zhou. Clinical observation of Shenling Baizhu Powder combined with triamcinolone acetonide in treating macular edema induced by retinal vein occlusion[J]. Journal of Translational Neuroscience,2021, 6(3): 30-36.

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https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2021.03.005
https://academic.hep.com.cn/jtn/EN/Y2021/V6/I3/30

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