Research progress of hsa-miR-495-3p and proteolipid protein 1 involvement in the pathogenesis of schizophrenia

doi:10.3868/j.issn.2096-0689.2022.01.003

Journal of Translational Neuroscience

2022, Vol. 7

Issue (1) : 11-14 https://doi.org/10.3868/j.issn.2096-0689.2022.01.003

Special Topic: Research Progress of Schizophrenia Related Genes

Research progress of hsa-miR-495-3p and proteolipid protein 1 involvement in the pathogenesis of schizophrenia

Zhilan Yang, Hongying Pan, Lan Jiang, Tiantian Jiang, Jie Wu^*

Department of Clinical Psychology, The Affiliated Mental Hospital of Kunming Medical University, Kunming 650000, China

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Abstract Schizophrenia (SCZ) is a serious mental illness whose etiology and pathogenesis are not yet clear. The level of miRNA may be a crucial factor in the occurrence and development of SCZ. This study found that miR-495 may regulate the susceptibility gene of SCZ and that proteolipid protein 1 (PLP1) as a risk gene for schizophrenia may be involved in its pathogenesis. In this article we review the research progress related to hsa-miR-495-3p (miR-495), PLP1, and schizophrenia.

Keywords schizophrenia (SCZ) hsa-miR-495-3p (miR-495) proteolipid protein 1 (PLP1)

Issue Date: 23 November 2022

Cite this article:

Zhilan Yang, Hongying Pan, Lan Jiang, Tiantian Jiang, Jie Wu. Research progress of hsa-miR-495-3p and proteolipid protein 1 involvement in the pathogenesis of schizophrenia[J]. Journal of Translational Neuroscience,2022, 7(1): 11-14.

URL:

https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2022.01.003
https://academic.hep.com.cn/jtn/EN/Y2022/V7/I1/11

[1]	Zhilan Yang, Hongying Pan, Lan Jiang, Tiankai Jiang, Yinhang Li, Jie Wu. Research progress on the mechanism of N6-methyladenosine methylation modification and proteolipid protein 1 gene in schizophrenia[J]. Journal of Translational Neuroscience, 2022, 7(1): 6-10.
[2]	Zhilan Yang, Hongying Pan, Lan Jiang, Yuhang Liang, Jie Wu. Research progress of the synapsin 2 gene polymorphism in the pathogenesis of schizophrenia[J]. Journal of Translational Neuroscience, 2022, 7(1): 1-5.

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