|
|
|
Flotillin-1 downregulates K+ current by directly coupling with Kv2.1 subunit |
Rui Liu,Guang Yang,Meng-Hua Zhou,Yu He,Yan-Ai Mei( ),Yu Ding() |
| School of Life Sciences, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai 200438, China |
|
|
|
|
|
|
Corresponding Author(s):
Yan-Ai Mei,Yu Ding
|
|
Issue Date: 20 June 2016
|
|
| 1 |
Babuke T, Ruonala M, Meister M, Amaddii M, Genzler C, Esposito A, Tikkanen R (2009) Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis. Cell Signal 21:1287–1297
https://doi.org/10.1016/j.cellsig.2009.03.012
|
| 2 |
Browman DT, Hoegg MB, Robbins SM (2007) The SPFH domain-containing proteins: more than lipid raft markers. Trends Cell Biol 17:394–402
https://doi.org/10.1016/j.tcb.2007.06.005
|
| 3 |
Kihira Y, Hermanstyne TO, Misonou H (2010) Formation of heteromeric Kv2 channels in mammalian brain neurons. J Biol Chem 285:15048–15055
https://doi.org/10.1074/jbc.M109.074260
|
| 4 |
Langhorst MF, Reuter A, Stuermer CA (2005) Scaffolding micro-domains and beyond: the function of reggie/flotillin proteins. Cell Mol Life Sci 62:2228–2240
https://doi.org/10.1007/s00018-005-5166-4
|
| 5 |
Langhorst MF, Reuter A, Jaeger FA, Wippich FM, Luxenhofer G, Plattner H, Stuermer CA (2008) Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2. Eur J Cell Biol 87:211–226
https://doi.org/10.1016/j.ejcb.2007.12.001
|
| 6 |
Martens JR, O’Connell K, Tamkun M (2004) Targeting of ion channels to membrane microdomains: localization of KV chan-nels to lipid rafts. Trends Pharmacol Sci 25:16–21
https://doi.org/10.1016/j.tips.2003.11.007
|
| 7 |
Monje FJ, Divisch I, Demit M, Lubec G, Pollak DD (2013) Flotillin-1 is an evolutionary-conserved memory-related protein up-regulated in implicit and explicit learning paradigms. Ann Med 45:301–307
https://doi.org/10.3109/07853890.2013.770637
|
| 8 |
Munderloh C, Solis GP, Bodrikov V, Jaeger FA, Wiechers M, Malaga-Trillo E, Stuermer CA (2009) Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons. J Neurosci 29:6607–6615
https://doi.org/10.1523/JNEUROSCI.0870-09.2009
|
| 9 |
O’Connell KM, Loftus R, Tamkun MM (2010) Localization-dependent activity of the Kv2.1 delayed-rectifier K+ channel. Proc Natl Acad Sci USA 107:12351–12356
https://doi.org/10.1073/pnas.1003028107
|
| 10 |
Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestol K, Danielsen HE, van Deurs B (2013) Flotillins as regulators of ErbB2 levels in breast cancer. Onco-gene 32:3443–3451
https://doi.org/10.1038/onc.2012.357
|
| 11 |
Solis GP, Schrock Y, Hulsbusch N, Wiechers M, Plattner H, Stuermer CA (2012) Reggies/flotillins regulate E-cadherin-medi-ated cell contact formation by affecting EGFR trafficking. Mol Biol Cell 23:1812–1825
https://doi.org/10.1091/mbc.E11-12-1006
|
| 12 |
Stuermer CA (2011) Microdomain-forming proteins and the role of the reggies/flotillins during axon regeneration in zebrafish. Biochim Biophys Acta 1812:415–422
https://doi.org/10.1016/j.bbadis.2010.12.004
|
| 13 |
Swanwick CC, Shapiro ME, Vicini S, Wenthold RJ (2010) Flotillin-1 promotes formation of glutamatergic synapses in hippocampal neurons. Dev Neurobiol 70:875–883
|
| 14 |
Yu FH, Yarov-Yarovoy V, Gutman GA, Catterall WA (2005) Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol Rev 57:387–395
https://doi.org/10.1124/pr.57.4.13
|
| 15 |
Zhuang JL, Wang CY, Zhou MH, Duan KZ, Mei YA (2012) TGF-beta1 enhances Kv2.1 potassium channel protein expression and promotes maturation of cerebellar granule neurons. J Cell Physiol 227:297–307
https://doi.org/10.1002/jcp.22735
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
