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Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers |
Zhifei Li1,2, Xueliang Ge3, Yixiao Zhang2, Lvqin Zheng1, Suparna Sanyal3( ), Ning Gao1,2( ) |
1. State Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing 100871, China 2. Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China 3. Department of Cell and Molecular Biology, Uppsala University, BMC, Box-596, Uppsala, Sweden |
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Corresponding Author(s):
Suparna Sanyal,Ning Gao
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Issue Date: 27 April 2018
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1 |
Ben-Shem A, Garreau de Loubresse N, Melnikov S, Jenner L, Yusupova G, Yusupov M (2011) The structure of the eukaryotic ribosome at 3.0 A resolution. Science 334:1524–1529
https://doi.org/10.1126/science.1212642
|
2 |
Byrgazov K, Grishkovskaya I, Arenz S, Coudevylle N, Temmel H, Wilson DN, Djinovic-Carugo K, Moll I (2015) Structural basis for the interaction of protein S1 with the Escherichia coli ribosome. Nucleic Acids Res 43:661–673
https://doi.org/10.1093/nar/gku1314
|
3 |
Cortes T, Schubert OT, Rose G, Arnvig KB, Comas I, Aebersold R, Young DB (2013) Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis. Cell Rep 5:1121–1131
https://doi.org/10.1016/j.celrep.2013.10.031
|
4 |
Hentschel J, Burnside C, Mignot I, Leibundgut M, Boehringer D, Ban N (2017) The complete structure of the mycobacterium smegmatis 70S ribosome. Cell Rep 20:149–160
https://doi.org/10.1016/j.celrep.2017.06.029
|
5 |
Jenner L, Demeshkina N, Yusupova G, Yusupov M (2010) Structural rearrangements of the ribosome at the tRNA proofreading step. Nat Struct Mol Biol 17:1072–1076
https://doi.org/10.1038/nsmb.1880
|
6 |
Khusainov I, Vicens Q, Bochler A, Grosse F, Myasnikov A, Menetret JF, Chicher J, Marzi S, Romby P, Yusupova Get al. (2016) Structure of the 70S ribosome from human pathogen Staphylococcus aureus. Nucleic Acids Res 44:10491–10504
|
7 |
Li X, Sun Q, Jiang C, Yang K, Hung LW, Zhang J, Sacchettini JC (2015) Structure of ribosomal silencing factor bound to mycobacterium tuberculosis ribosome. Structure 23:1858–1865
https://doi.org/10.1016/j.str.2015.07.014
|
8 |
Pulk A, Cate JH (2013) Control of ribosomal subunit rotation by elongation factor G. Science 340:1235970
https://doi.org/10.1126/science.1235970
|
9 |
Ramakrishnan V (2014) The ribosome emerges from a black box. Cell 159:979–984
https://doi.org/10.1016/j.cell.2014.10.052
|
10 |
Schmalisch M, Langbein I, Stulke J (2002) The general stress protein Ctc of Bacillus subtilis is a ribosomal protein. J Mol Microbiol Biotechnol 4:495–501
|
11 |
Selmer M, Dunham CM, Murphy FV, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V (2006) Structure of the 70S ribosome complexed with mRNA and tRNA. Science 313:1935–1942
https://doi.org/10.1126/science.1131127
|
12 |
Shasmal M, Sengupta J (2012) Structural diversity in bacterial ribosomes: mycobacterial 70S ribosome structure reveals novel features. PLoS ONE 7:e31742
https://doi.org/10.1371/journal.pone.0031742
|
13 |
Shell SS, Wang J, Lapierre P, Mir M, Chase MR, Pyle MM, Gawande R, Ahmad R, Sarracino DA, Ioerger TRet al. (2015) Leaderless transcripts and small proteins are common features of the mycobacterial translational landscape. PLoS Genet 11:e1005641
https://doi.org/10.1371/journal.pgen.1005641
|
14 |
Wilson DN (2014) Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Nat Rev Microbiol 12:35–48
https://doi.org/10.1038/nrmicro3155
|
15 |
Yusupova G, Yusupov M (2017) Crystal structure of eukaryotic ribosome and its complexes with inhibitors. Philos Trans R Soc Lond B Biol Sci372
https://doi.org/10.1098/rstb.2016.0184
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