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Frontiers of Agriculture in China

ISSN 1673-7334

ISSN 1673-744X(Online)

CN 11-5729/S

Front Agric Chin    2009, Vol. 3 Issue (2) : 226-230     DOI: 10.1007/s11703-009-0037-7
Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine
Bin WANG1(), Yulong YIN2()
1. Department of Food Engineering, Jiangsu Food Science College, Huai’an 223003, China; 2. Laboratory of Animal Nutrition and Health and Key Laboratory of Agro-Ecology, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China
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Phosphate (Pi) plays important roles in growth, development, bone mineralization, energy metabolism, nucleic acid synthesis, cell signaling, and acid–base regulation. The rate of intestinal absorption of Pi is a major determinant of Pi homeostasis. The type IIb sodium-dependent Pi cotransporter (NaPi-IIb) is responsible for intestinal Pi absorption. Many physiological factors regulate the rate of Pi absorption via modulating the expression of NaPi-IIb in the intestine. In this review, we summarize the role of these factors in the regulation of NaPi-IIb expression in the intestine.

Keywords NaPi-IIb      expression      intestine      regulation     
Corresponding Authors: WANG Bin,; YIN Yulong,   
Issue Date: 05 June 2009
URL:     OR
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