Cronobacter spp., foodborne pathogens threatening neonates and infants
Qiming CHEN1,2, Yang ZHU3, Zhen QIN1,2, Yongjun QIU1,2, Liming ZHAO1,2()
1. School of Biotechnology, State Key Laboratory of Bioreactor Engineering, R&D Center of Separation and Extraction Technology in Fermentation Industry, East China University of Science and Technology, Shanghai 200237, China 2. Shanghai Collaborative Innovation Center for Biomanufacturing Technology (SCICBT), Shanghai 200237, China 3. Bioprocess Engineering Group, Agrotechnology and Food Sciences, Wageningen University and Research, 6700 AA Wageningen, the Netherlands
Cronobacter spp. (formerly Enterobacter sakazakii) are special foodborne pathogens. Cronobacter infection can cause necrotizing enterocolitis, sepsis and meningitis in all age groups, especially neonates and infants, with a high fatality of up to 80%, although the infection is rare. Outbreaks of Cronobacter infection are epidemiologically proven to be associated with contaminated powdered infant formula (PIF). Cronobacter spp. can resist dry environments and survive for a long period in food with low water activity. Therefore, Cronobacter spp. have become serious pathogens of neonates and infants, as well as in the dairy industry. In this review, we present the taxonomy, pathogenesis, resistance, detection and control of Cronobacter spp.
Food of plant origin and environmental samples from farms and supermarkets
Czech Republic
Vojkovska et al.[64]
2017
Retail foods
Brazil
Brandão et al.[65]
2017
Baby foods and baby food ingredients
Turkey
Heperkan et al.[66]
Tab.2
Fig.1
Target gene
Genus/Species
Reference
dnaG
Genus
Seo et al.[92]
gluB
Genus
Lehner et al.[93]
tRNAGlu
Genus
Hassan et al.[94]
23S rDNA
Genus
Derzelle et al.[95]
16S rDNA
Genus
Hassan et al.[94]
wehC, wehI
Species
Mullane et al.[96]
zpx
Genus
Jaradat et al.[97]
wzx
Genus
Jarvis et al.[98]
gyrB
Genus
Huang et al.[99]
grxB
Genus
Dong et al.[100]
ompA
Genus
Zimmermann et al.[101]
MMS
Genus
Tan et al.[102]
cgcA
Species
Hu et al.[103]
rpoB
Genus
Li et al.[104]
ITS
Genus
Liu et al.[105]
PapC
Species
Chen et al.[106]
gluB
Species
YE et al.[107]
Tab.3
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