Observations on potential novel transcripts from RNA-Seq data
Observations on potential novel transcripts from RNA-Seq data
Chao YE, Linxi LIU, Xi WANG, Xuegong ZHANG()
Key Laboratory of Bioinformatics and Bioinformatics Division, Ministry of Education, Tsinghua National Laboratory for Information Science and Technology/Department of Automation, Tsinghua University, Beijing 100084, China
With the rapid development of next generation deep sequencing technologies, sequencing cDNA reverse-transcribed from RNA molecules (RNA-Seq) has become a key approach in studying gene expression and transcriptomes. Because RNA-Seq does not rely on annotation of known genes, it provides the opportunity of discovering transcripts that have not been annotated in current databases. Studying the distribution of RNA-Seq signals and a systematic view on the potential new transcripts revealed from the signals is an important step toward the understanding of transcriptomes.
. Observations on potential novel transcripts from RNA-Seq data[J]. Frontiers of Electrical and Electronic Engineering in China, 2011, 6(2): 275-282.
Chao YE, Linxi LIU, Xi WANG, Xuegong ZHANG. Observations on potential novel transcripts from RNA-Seq data. Front Elect Electr Eng Chin, 2011, 6(2): 275-282.
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