1. State Key Joint Laboratory of Environmental Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China 2. Environmental Engineering Programs, The Pennsylvania State University, Middletown, PA 17057, USA
Disinfection by-products (DBPs) are regulated in drinking water in a number of countries. This critical review focuses on the issues associated with DBP regulatory compliance, including methods for DBP analysis, occurrence levels, the regulation comparison among various countries, DBP compliance strategies, and emerging DBPs. The regulation comparison between China and the United States (US) indicated that the DBP regulations in China are more stringent based on the number of regulated compounds and maximum levels. The comparison assessment using the Information Collection Rule (ICR) database indicated that the compliance rate of 500 large US water plants under the China regulations is much lower than that under the US regulations (e.g. 62.2% versus 89.6% for total trihalomethanes). Precursor removal and alternative disinfectants are common practices for DBP regulatory compliance. DBP removal after formation, including air stripping for trihalomethane removal and biodegradation for haloacetic acid removal, have gained more acceptance in DBP control. Formation of emerging DBPs, including iodinated DBPs and nitrogenous DBPs, is one of unintended consequences of precursor removal and alternative disinfection. At much lower levels than carbonaceous DBPs, however, emerging DBPs have posed higher health risks.
R Sadiq, M J Rodriguez. Disinfection by-products (DBPs) in drinking water and predictive models for their occurrence: a review. Science of the Total Environment, 2004, 321(1–3): 21–46 https://doi.org/10.1016/j.scitotenv.2003.05.001
pmid: 15050383
2
Y F Xie. Disinfection Byproducts in Drinking Water—Formation, Analysis, and Control. Washington, DC: Lewis Publishers, 2004
3
S D Richardson, M J Plewa, E D Wagner, R Schoeny, D M Demarini. Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutation Research, 2007, 636(1–3): 178–242 https://doi.org/10.1016/j.mrrev.2007.09.001
pmid: 17980649
4
T Karanfil, S W Krasner, P Westerhoff, Y F Xie. Recent advances in Disinfection by-product: Formation, occurrence, health effects, and regulations. In: T Karanfil, S W Krasner, P Westerhoff, Y F Xie, editors, Disinfection By-Products in Drinking Water – Occurrence, Formation, Health Effects, and Control. Washington, DC: American Chemical Society, 2008, 2–19
5
S W Krasner. The formation and control of emerging disinfection by-products of health concern. Philosophical Transactions of the Royal Society A—Mathematical Physical and Engineering Sciences, 2009, 367(1904): 4077–4095 https://doi.org/10.1098/rsta.2009.0108
pmid: 19736234
6
T Bond, M R Templeton, N Graham. Precursors of nitrogenous disinfection by-products in drinking water—a critical review and analysis. Journal of Hazardous Materials, 2012, 235-236: 1–16 https://doi.org/10.1016/j.jhazmat.2012.07.017
pmid: 22846217
7
A D Shah, W A Mitch. Halonitroalkanes, halonitriles, haloamides, and N-nitrosamines: a critical review of nitrogenous disinfection byproduct formation pathways. Environmental Science & Technology, 2012, 46(1): 119–131 https://doi.org/10.1021/es203312s
pmid: 22112205
8
GB5749–2006. P.R. China Standards for Drinking Water Quality. Beijing: Department of Health, P.R. China, 2006 (in Chinese)
9
Y F Xie. Disinfection by-product analysis in drinking water. American Laboratory, 2000, 32(22): 50–54
10
GB/T 5750.10–2006. P.R. China Standards Examination Methods for Drinking Water – Disinfection By-products Parameters. Beijing: Department of Health, P.R. China, 2006 (in Chinese)
11
X M Wang, X L Zhang, H W Yang, J S Zhang, L J Liu, B Liu, Y F Xie. Comparison of methods for chloral hydrate analysis in drinking water. Water & Wastewater Engineering, 2013, 39 (supplementary): 125–128 (in Chinese)
12
Y F Xie, C J Hwang. Cyanogen chloride and cyanogen bromide analysis in drinking water. In: R A Meyers, ed. Encyclopedia of Analytical Chemistry. Hoboken: John Wiley & Sons, 2006
13
Y F Xie, D A Reckhow. A rapid and simple analytical method for cyanogen chloride and cyanogen-bromide in drinking water. Water Research, 1993, 27(3): 507–511 https://doi.org/10.1016/0043-1354(93)90051-I
14
S D Richardson. Disinfection by-products and other emerging contaminants in drinking water. Trace-Trends in Analytical Chemistry, 2003, 22(10): 666–684 https://doi.org/10.1016/S0165-9936(03)01003-3
15
H S Weinberg. Modern approaches to the analysis of disinfection by-products in drinking water. Philosophical Transactions of the Royal Society A-Mathematical Physical and Engineering Sciences, 2009, 367(1904): 4097–4118 https://doi.org/10.1098/rsta.2009.0130
pmid: 19736235
16
R Loos, D Barcel�. Determination of haloacetic acids in aqueous environments by solid-phase extraction followed by ion-pair liquid chromatography-electrospray ionization mass spectrometric detection. Journal of Chromatography. A, 2001, 938(1–2): 45–55 https://doi.org/10.1016/S0021-9673(01)01092-5
pmid: 11771846
17
L Meng, S Wu, F Ma, A Jia, J Hu. Trace determination of nine haloacetic acids in drinking water by liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography. A, 2010, 1217(29): 4873–4876 https://doi.org/10.1016/j.chroma.2010.04.074
pmid: 20538280
18
S D Richardson. The role of GC-MS and LC-MS in the discovery of drinking water disinfection by-products. Journal of Environmental Monitoring, 2002, 4(1): 1–9 https://doi.org/10.1039/b105578j
pmid: 11871687
19
S D Richardson. Environmental mass spectrometry: emerging contaminants and current issues. Analytical Chemistry, 2008, 80(12): 4373–4402 https://doi.org/10.1021/ac800660d
pmid: 18498180
20
X Zhang, R A Minear, Y Guo, C J Hwang, S E Barrett, K Ikeda, Y Shimizu, S Matsui. An electrospray ionization-tandem mass spectrometry method for identifying chlorinated drinking water disinfection byproducts. Water Research, 2004, 38(18): 3920–3930 https://doi.org/10.1016/j.watres.2004.06.022
pmid: 15380982
21
X Zhang, J W Talley, B Boggess, G Ding, D Birdsell. Fast selective detection of polar brominated disinfection byproducts in drinking water using precursor ion scans. Environmental Science & Technology, 2008, 42(17): 6598–6603 https://doi.org/10.1021/es800855b
pmid: 18800536
22
X Zhang, R A Minear, S E Barrett. Characterization of high molecular weight disinfection byproducts from chlorination of humic substances with/without coagulation pretreatment using UF-SEC-ESI-MS/MS. Environmental Science & Technology, 2005, 39(4): 963–972 https://doi.org/10.1021/es0490727
pmid: 15773467
23
Y Xie, H J Zhou. Biologically active carbon for HAA removal: part II, column study. Journal—American Water Works Association, 2002, 94(5): 126–134
24
E T Urbansky. Techniques and methods for the determination of haloacetic acids in potable water. Journal of Environmental Monitoring, 2000, 2(4): 285–291 https://doi.org/10.1039/b002977g
pmid: 11249781
25
P Kubáň, N Makarõtševa, I K Kiplagat, M Kaljurand. Determination of five priority haloacetic acids by capillary electrophoresis with contactless conductivity detection and solid phase extraction preconcentration. Journal of Separation Science, 2012, 35(5–6): 666–673 https://doi.org/10.1002/jssc.201100944
pmid: 22517640
26
C Zwierner, S D Richardson. Analysis of disinfection by-products in drinking water by LC–MS and related MS techniques. Trace-Trends in Analytical Chemistry, 2005, 24(7): 613–621 https://doi.org/10.1016/j.trac.2005.03.014
27
C Zwiener, F H Frimmel. LC-MS analysis in the aquatic environment and in water treatment technology—A critical review. Part II: Applications for emerging contaminants and related pollutants, microorganisms and humic acids. Analytical and Bioanalytical Chemistry, 2004, 378(4): 862–874 https://doi.org/10.1007/s00216-003-2412-1
pmid: 14673565
28
Y Liu, S Mou. Determination of bromate and chlorinated haloacetic acids in bottled drinking water with chromatographic methods. Chemosphere, 2004, 55(9): 1253–1258 https://doi.org/10.1016/j.chemosphere.2003.12.023
pmid: 15081766
29
S W Krasner, M J McGuire, J G Jacangelo, N L Patania, K M Reagan, E M Aieta. The occurrence of disinfection by-products in United-States drinking-water. Journal—American Water Works Association, 1989, 81(8): 41–53
30
S W Krasner, H S Weinberg, S D Richardson, S J Pastor, R Chinn, M J Sclimenti, G D Onstad, A D Thruston Jr, A D Thruston. Occurrence of a new generation of disinfection byproducts. Environmental Science & Technology, 2006, 40(23): 7175–7185 https://doi.org/10.1021/es060353j
pmid: 17180964
31
J G Pressman, S D Richardson, T F Speth, R J Miltner, M G Narotsky, E S Hunter 3rd, G E Rice, L K Teuschler, A McDonald, S Parvez, S W Krasner, H S Weinberg, A B McKague, C J Parrett, N Bodin, R Chinn, C F Lee, J E Simmons. Concentration, chlorination, and chemical analysis of drinking water for disinfection byproduct mixtures health effects research: U.S.EPA’s Four Lab Study. Environmental Science & Technology, 2010, 44(19): 7184–7192 https://doi.org/10.1021/es9039314
pmid: 20496936
32
M J McGuire, J L McLain, A Obolensky. Information collection rule data analysis. Denver: American Water Works Association Research Foundation, 2002
33
A Obolensky, P C Singer. Halogen substitution patterns among disinfection byproducts in the information collection rule database. Environmental Science & Technology, 2005, 39(8): 2719–2730 https://doi.org/10.1021/es0489339
pmid: 15884369
34
A Obolensky, P C Singer, H M Shukairy. Information collection rule data evaluation and analysis to support impacts on disinfection by-product formation. Journal of Environmental Engineering, 2007, 39(8): 53–63 https://doi.org/10.1061/(ASCE)0733-9372(2007)133:1(53)
35
W A Mitch, S W Krasner, P Westerhoff, A Dotson. Occurrence and formation of nitrogenous disinfection by-products. Denver: Water Research Foundation, 2009
36
M J McGuire, R G Meadow. AWWARF trihalomethane survey. Journal—American Water Works Association, 1988, 80(1): 61–68
K J Lee, B H Kim, J E Hong, H S Pyo, S J Park, D W Lee. A study on the distribution of chlorination by-products (CBPs) in treated water in Korea. Water Research, 2001, 35(12): 2861–2872 https://doi.org/10.1016/S0043-1354(00)00583-2
pmid: 11471686
H Ding, L Meng, H Zhang, J Yu, W An, J Hu, M Yang. Occurrence, profiling and prioritization of halogenated disinfection by-products in drinking water of China. Environmental Science—Processes & Impacts, 2013, 15(7): 1424–1429 https://doi.org/10.1039/c3em00110e
pmid: 23743579
43
US Environmental Protection Agency. National primary drinking water regulations: disinfectants and disinfection byproducts. Federal Register, 1998, 63: 69390–69476
44
US Environmental Protection Agency. National primary drinking water regulations: stage 2 disinfectants and disinfection byproducts rule. Federal Register, 2006, 71: 388–493
45
CDW. Guidelines for Canadian Drinking Water Quality Summary Table. Committee on Drinking Water of the of the Federal-Provincial-Territorial Committee on Health and the Environment, Canada, 2012
46
EU. Council directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption, 1998
47
S K Golfinopoulos, A D Nikolaou. Survey of disinfection by-products in drinking water in Athens, Greece. Desalination, 2005, 176(1–3): 13–24 https://doi.org/10.1016/j.desal.2004.10.029
48
WHO. Guidelines for Drinking-water Quality. 4th edition. World Health Organization, 2011
49
MHLW. Ministry of Health, Labour and Welfare, Japan
50
NHMRC, NRMMC. Australian Drinking Water Guidelines 6. Commonwealth of Australia, 2011
51
T Bond, J Huang, M R Templeton, N Graham. Occurrence and control of nitrogenous disinfection by-products in drinking water—a review. Water Research, 2011, 45(15): 4341–4354 https://doi.org/10.1016/j.watres.2011.05.034
pmid: 21705040
K Gopal, S S Tripathy, J L Bersillon, S P Dubey. Chlorination byproducts, their toxicodynamics and removal from drinking water. Journal of Hazardous Materials, 2007, 140(1–2): 1–6 https://doi.org/10.1016/j.jhazmat.2006.10.063
pmid: 17129670
54
K Watson, M J Farr�, N Knight. Strategies for the removal of halides from drinking water sources, and their applicability in disinfection by-product minimisation: a critical review. Journal of Environmental Management, 2012, 110: 276–298 https://doi.org/10.1016/j.jenvman.2012.05.023
pmid: 22810000
55
W A Mitch, J O Sharp, R P Trussell, R L Valentine, L Alvarez-Cohen, D L Sedlak. N-nitrosodimethylamine (NDMA) as a drinking water contaminant: a review. Environmental Engineering Science, 2003, 20(5): 389–404 https://doi.org/10.1089/109287503768335896
56
I M Schreiber, W A Mitch. Influence of the order of reagent addition on NDMA formation during chloramination. Environmental Science & Technology, 2005, 39(10): 3811–3818 https://doi.org/10.1021/es0483286
pmid: 15952390
57
G H Hua, D A Reckhow. DBP formation during chlorination and chloramination: Effect of reaction time, pH, dosage, and temperature. Journal—American Water Works Association, 2008, 100(8): 82–95
58
H H Tung, R F Unz, Y F Xie. Haloacetic acid removal by granular activated carbon adsorption. Journal—American Water Works Association, 2006, 98(6): 107–112
59
Y F Xie, H J Zhou, J P Romano. Development of a capillary electrophoresis method for haloacetic acids. Abstracts of Papers of the American Chemical Society, 1999, 217: 742–742
60
H W Wu, Y F Xie. Effects of EBCT and water temperature on HAA removal using BAC. Journal—American Water Works Association, 2005, 97(11): 94–101
61
H H Tung, Y F Xie. Association between haloacetic acid degradation and heterotrophic bacteria in water distribution systems. Water Research, 2009, 43(4): 971–978 https://doi.org/10.1016/j.watres.2008.11.041
pmid: 19070347
62
M J Rodriguez, J B S�rodes, P Levallois. Behavior of trihalomethanes and haloacetic acids in a drinking water distribution system. Water Research, 2004, 38(20): 4367–4382 https://doi.org/10.1016/j.watres.2004.08.018
pmid: 15556212
63
B H Boyden, D T Banh, H K Huckabay, J B Fernandes. Using inclined cascade aeration to strip chlorinated VOCs from drinking-water. Journal—American Water Works Association, 1992, 84(5): 62–69
64
C Velazquez, L A Estevez. Stripping of trihalomethanes from drinking-water in a bubble-column aerator. American Institute of Chemical Engineers Journal, 1992, 38(2): 211–218 https://doi.org/10.1002/aic.690380206
65
S R Sherant. Trihalomethane Control by Aeration. Dissertation for the Master Degree. Pennsylvania: The Pennsylvania State University, 2008
66
S R Sherant, Y D Hardin, Y F Xie. A simple technology for THM control in consecutive systems. In: Proceedings of the American Water Works Association Water Quality Technology Conference, 2007
67
E Brooke, M R Collins. Post treatment aeration to reduce THMs. Journal—American Water Works Association, 2011, 103(10): 84–96
68
R M Hozalski, L Zhang, W A Arnold. Reduction of haloacetic acids by Fe0: implications for treatment and fate. Environmental Science & Technology, 2001, 35(11): 2258–2263 https://doi.org/10.1021/es001785b
pmid: 11414027
69
L Zhang, W A Arnold, R M Hozalski. Kinetics of haloacetic acid reactions with Fe(0). Environmental Science & Technology, 2004, 38(24): 6881–6889 https://doi.org/10.1021/es049267e
pmid: 15669353
70
C R Pearson, R M Hozalski, W A Arnold. Degradation of chloropicrin in the presence of zero-valent iron. Environmental Toxicology and Chemistry, 2005, 24(12): 3037–3042 https://doi.org/10.1897/04-614Ra.1
pmid: 16445082
71
C Chen, X Wang, Y Chang, H Liu. Dechlorination of disinfection by-product monochloroacetic acid in drinking water by nanoscale palladized iron bimetallic particle. Journal of Environmental Sciences (China), 2008, 20(8): 945–951 https://doi.org/10.1016/S1001-0742(08)62191-9
pmid: 18817073
72
T Li, Y Chen, P Wan, M Fan, X J Yang. Chemical degradation of drinking water disinfection byproducts by millimeter-sized particles of iron-silicon and magnesium-aluminum alloys. Journal of the American Chemical Society, 2010, 132(8): 2500–2501 https://doi.org/10.1021/ja908821d
pmid: 20143771
73
X Y Wang, P Ning, H L Liu, J Ma. Dechlorination of chloroacetic acids by Pd/Fe nanoparticles: Effect of dying method on metallic activity and the parameter optimization. Applied Catalysis B: Environmental, 2010, 94(1–2): 55–63 https://doi.org/10.1016/j.apcatb.2009.10.020
74
S Tang, X M Wang, H W Yang, Y F Xie. Haloacetic acid removal by sequential zero-valent iron reduction and biologically active carbon degradation. Chemosphere, 2013, 90(4): 1563–1567 https://doi.org/10.1016/j.chemosphere.2012.09.046
pmid: 23079162
75
Y T Woo, D Lai, J L McLain, M K Manibusan, V Dellarco. Use of mechanism-based structure-activity relationships analysis in carcinogenic potential ranking for drinking water disinfection by-products. Environmental Health Perspectives, 2002, 110(Suppl 1): 75–87 https://doi.org/10.1289/ehp.02110s175
pmid: 11834465
76
B Cancho, F Ventura, M Galceran, A Diaz, S Ricart. Determination, synthesis and survey of iodinated trihalomethanes in water treatment processes. Water Research, 2000, 34(13): 3380–3390 https://doi.org/10.1016/S0043-1354(00)00079-8
77
P H Chen, S D Richardson, S W Krasner, G Majetich, G L Glish. Hydrogen abstraction and decomposition of bromopicrin and other trihalogenated disinfection byproducts by GC/MS. Environmental Science & Technology, 2002, 36(15): 3362–3371 https://doi.org/10.1021/es0205582
pmid: 12188366
78
C K Wang, X J Zhang, J Wang, C Chen. Detecting N-nitrosamines in water treatment plants and distribution systems in China using ultra-performance liquid chromatography-tadenm mass spectrometry. Frontiers of Environmental Science & Engineering, 2012, 6(6): 770–777
79
Y Y Zhao, J Boyd, S E Hrudey, X F Li. Characterization of new nitrosamines in drinking water using liquid chromatography tandem mass spectrometry. Environmental Science & Technology, 2006, 40(24): 7636–7641 https://doi.org/10.1021/es061332s
pmid: 17256506
80
A I Egorov, A A Tereschenko, L M Altshul, T Vartiainen, D Samsonov, B LaBrecque, J M�ki-Paakkanen, N L Drizhd, T E Ford. Exposures to drinking water chlorination by-products in a Russian city. International Journal of Hygiene and Environmental Health, 2003, 206(6): 539–551 https://doi.org/10.1078/1438-4639-00244
pmid: 14626901
81
J M Boyd, S E Hrudey, S D Richardson, X F Li. Solid-phase extraction and high-performance liquid chromatography mass spectrometry analysis of nitrosamines in treated drinking water and wastewater. Trace-Trends in Analytical Chemistry, 2011, 30(9): 1410–1421 https://doi.org/10.1016/j.trac.2011.06.009
82
S W Krasner, W A Mitch, D L McCurry, D Hanigan, P Westerhoff. Formation, precursors, control, and occurrence of nitrosamines in drinking water: a review. Water Research, 2013, 47(13): 4433–4450 https://doi.org/10.1016/j.watres.2013.04.050
pmid: 23764594
83
H Zhao, H Liu, C Hu, J Qu. Effect of aluminum speciation and structure characterization on preferential removal of disinfection byproduct precursors by aluminum hydroxide coagulation. Environmental Science & Technology, 2009, 43(13): 5067–5072 https://doi.org/10.1021/es8034347
pmid: 19673308
84
V Uyak, S Yavuz, I Toroz, A Ozaydin, E A Genceli. Disinfection by-products precursors removal by enhanced coagulation and PAC adsorption. Desalination, 2007, 216(1–3): 334–344 https://doi.org/10.1016/j.desal.2006.11.026
85
G Hua, D A Reckhow. Characterization of disinfection byproduct precursors based on hydrophobicity and molecular size. Environmental Science & Technology, 2007, 41(9): 3309–3315 https://doi.org/10.1021/es062178c
pmid: 17539542
86
L Liang, P C Singer. Factors influencing the formation and relative distribution of haloacetic acids and trihalomethanes in drinking water. Environmental Science & Technology, 2003, 37(13): 2920–2928 https://doi.org/10.1021/es026230q
pmid: 12875395
87
N Ates, L Yilmaz, M Kitis, U Yetis. Removal of disinfection by-product precursors by UF and NF membranes in low-SUVA waters. Journal of Membrane Science, 2009, 328(1–2): 104–112 https://doi.org/10.1016/j.memsci.2008.11.044
88
S Chellam. Effects of nanofiltration on trihalomethane and haloacetic acid precursor removal and speciation in waters containing low concentrations of bromide ion. Environmental Science & Technology, 2000, 34(9): 1813–1820 https://doi.org/10.1021/es991153t
89
S Chellam, R R Sharma, G R Shetty, Y Wei. Nanofiltration of pretreated Lake Houston water- Disinfection by-product speciation, relationships, and control. Separation and Purification Technology, 2008, 64(2): 160–169 https://doi.org/10.1016/j.seppur.2008.09.007
90
C J Harrison, Y A Le Gouellec, R C Cheng, A E Childress. Bench-scale testing of nanofiltration for seawater desalination. Journal of Environmental Engineering, 2007, 133(11): 1004–1014 https://doi.org/10.1061/(ASCE)0733-9372(2007)133:11(1004)
91
C K Wang, X J Zhang, C Chen, J Wang. Factors controlling N-nitrosodimethylamine (NDMA) formation from dissolved organic matter. Frontiers of Environmental Science & Engineering, 2013, 7(2): 151–157 https://doi.org/10.1007/s11783-013-0482-7
92
S H Park, S Wei, B Mizaikoff, A E Taylor, C Favero, C H Huang, C H Huang. Degradation of amine-based water treatment polymers during chloramination as N-nitrosodimethylamine (NDMA) precursors. Environmental Science & Technology, 2009, 43(5): 1360–1366 https://doi.org/10.1021/es802732z
pmid: 19350904
93
W A Mitch, D L Sedlak. Formation of N-nitrosodimethylamine (NDMA) from dimethylamine during chlorination. Environmental Science & Technology, 2002, 36(4): 588–595 https://doi.org/10.1021/es010684q
pmid: 11878371
94
K D Kohut, S A Andrews. Polyelectrolyte age and N-nitrosodimethylamine formation in drinking water treatment. Water Quality Research Journal of Canada, 2003, 38(4): 719–735
95
Y Bichsel, U von Gunten. Formation of iodo-trihalomethanes during disinfection and oxidation of iodide containing waters. Environmental Science & Technology, 2000, 34(13): 2784–2791 https://doi.org/10.1021/es9914590
96
S D Richardson, F Fasano, J J Ellington, F G Crumley, K M Buettner, J J Evans, B C Blount, L K Silva, T J Waite, G W Luther, A B Mckague, R J Miltner, E D Wagner, M J Plewa. Occurrence and mammalian cell toxicity of iodinated disinfection byproducts in drinking water. Environmental Science & Technology, 2008, 42(22): 8330–8338 https://doi.org/10.1021/es801169k
pmid: 19068814
97
Z Chen, R L Valentine. The influence of the pre-oxidation of natural organic matter on the formation of N-nitrosodimethylamine (NDMA). Environmental Science & Technology, 2008, 42(14): 5062–5067 https://doi.org/10.1021/es8006673
pmid: 18754348
98
A D Shah, S W Krasner, C F T Lee, U von Gunten, W A Mitch. Trade-offs in disinfection byproduct formation associated with precursor preoxidation for control of N-nitrosodimethylamine formation. Environmental Science & Technology, 2012, 46(9): 4809–4818 https://doi.org/10.1021/es204717j
pmid: 22463122
99
L Padhye, Y Luzinova, M Cho, B Mizaikoff, J H Kim, C H Huang. PolyDADMAC and dimethylamine as precursors of N-nitrosodimethylamine during ozonation: reaction kinetics and mechanisms. Environmental Science & Technology, 2011, 45(10): 4353–4359 https://doi.org/10.1021/es104255e
pmid: 21504218
100
J Hoigne, H Bader. The formation of trichloronitromethane (chloropicrin) and chloroform in a combined ozonation chlorination treatment of drinking-water. Water Research, 1988, 22(3): 313–319 https://doi.org/10.1016/S0043-1354(88)90120-0
D A Reckhow, K G Linden, J Kim, H Shemer, G Makdissy. Effect of UV treatment on DBP formation. Journal—American Water Works Association, 2010, 102(6): 100–113
103
A D Shah, A D Dotson, K G Linden, W A Mitch. Impact of UV disinfection combined with chlorination/chloramination on the formation of halonitromethanes and haloacetonitriles in drinking water. Environmental Science & Technology, 2011, 45(8): 3657–3664 https://doi.org/10.1021/es104240v
pmid: 21417331
