Identification of important precursors and theoretical toxicity evaluation of byproducts driving cytotoxicity and genotoxicity in chlorination

doi:10.1007/s11783-019-1204-6

Frontiers of Environmental Science & Engineering

2020, Vol. 14

Issue (2): 25 https://doi.org/10.1007/s11783-019-1204-6

本期目录

Identification of important precursors and theoretical toxicity evaluation of byproducts driving cytotoxicity and genotoxicity in chlorination

Qian-Yuan Wu¹, Yi-Jun Yan¹, Yao Lu², Ye Du²(

), Zi-Fan Liang¹, Hong-Ying Hu^2,³

¹. Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China
². Shenzhen Environmental Science and New Energy Technology Engineering Laboratory, Tsinghua-Berkeley Shenzhen Institute, Shenzhen 518055, China
³. Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing 100084, China

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Abstract：

• NOM formed more C-DBPs while amino acids formed more N-DBPs during chlorination

• Aspartic acid and asparagine showed the highest toxicity index during chlorination

• Dichloroacetonitrile might be a driving DBP for cytotoxicity and genotoxicity

• Dichloroacetonitrile dominated the toxicity under different chlorination conditions

Chlorination, the most widely used disinfection process for water treatment, is unfortunately always accompanied with the formation of hazardous disinfection byproducts (DBPs). Various organic matter species, like natural organic matter (NOM) and amino acids, can serve as precursors of DBPs during chlorination but it is not clear what types of organic matter have higher potential risks. Although regulation of DBPs such as trihalomethanes has received much attention, further investigation of the DBPs driving toxicity is required. This study aimed to identify the important precursors of chlorination by measuring DBP formation from NOM and amino acids, and to determine the main DBPs driving toxicity using a theoretical toxicity evaluation of contributions to the cytotoxicity index (CTI) and genotoxicity index (GTI). The results showed that NOM mainly formed carbonaceous DBPs (C-DBPs), such as trichloromethane, while amino acids mainly formed nitrogenous DBPs (N-DBPs), such as dichloroacetonitrile (DCAN). Among the DBPs, DCAN had the largest contribution to the toxicity index and might be the main driver of toxicity. Among the precursors, aspartic acid and asparagine gave the highest DCAN concentration (200 g/L) and the highest CTI and GTI. Therefore, aspartic acid and asparagine are important precursors for toxicity and their concentrations should be reduced as much as possible before chlorination to minimize the formation of DBPs. During chlorination of NOM, tryptophan, and asparagine solutions with different chlorine doses and reaction times, changes in the CTI and GTI were consistent with changes in the DCAN concentration.

Key words： Chlorination Dichloroacetonitrile Aspartic acid Asparagine Toxicity index

收稿日期: 2019-06-26 出版日期: 2019-12-27

Corresponding Author(s): Ye Du

引用本文:

. [J]. Frontiers of Environmental Science & Engineering, 2020, 14(2): 25.
Qian-Yuan Wu, Yi-Jun Yan, Yao Lu, Ye Du, Zi-Fan Liang, Hong-Ying Hu. Identification of important precursors and theoretical toxicity evaluation of byproducts driving cytotoxicity and genotoxicity in chlorination. Front. Environ. Sci. Eng., 2020, 14(2): 25.

链接本文:

https://academic.hep.com.cn/fese/CN/10.1007/s11783-019-1204-6
https://academic.hep.com.cn/fese/CN/Y2020/V14/I2/25

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