Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance
Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance
XIA Yanzhi1, WAN Xuedong2, DUAN Qiuhong2, HE Shansu2, WANG Ximing2
1.Department of Medical Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 2.Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;
Abstract:Elevated plasma levels of free fatty acids (FFAs) may contribute to insulin resistance (IR) that is characteristic of type 2 diabetes mellitus. In this study, we investigated the effects of two fatty acids, palmitate (PA) and arach
出版日期: 2007-06-05
引用本文:
. Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance[J]. Frontiers of Medicine in China, 2007, 1(2): 200-206.
XIA Yanzhi, WAN Xuedong, DUAN Qiuhong, HE Shansu, WANG Ximing. Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance. Front. Med., 2007, 1(2): 200-206.