Antiviral antibodies against SARS-CoV-2 did ?not decline within 4 months after diagnosis
Tan et al. [6] September, 2020
Retrospective study
N = 64 (15 cases at 2 weeks ?to 1 month, 20 cases at ?1–2 month, 17 cases at ?6–8 months, 12 healthy ?donors) Shanghai, China
Within 6-7 months
S-protein IgG (ELISA) N-protein IgG (ELISA) Neutralizing antibody ?(pseudovirus neutralization assay) T cell response (the interferon-g ?producing CD4+ T cells and CD8+ ?T cells)
IgG and neutralizing antibodies were ?detectable at 6-7 months after diagnosis No difference in blocking the cell-entry of ?the 614D and 614G variants of SARS-CoV-?2 by neutralizing activities Interferon g-producing CD4+ and CD8+ ?cells increased in response to SARS-CoV-2 ?antigen stimulation as compared with non-?stimulated samples at 6–7 months
Tab.1
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