Design and evaluation of a novel biopsy needle with hemostatic function

doi:10.1007/s11465-022-0738-7

Frontiers of Mechanical Engineering

2023, Vol. 18

Issue (2): 22 https://doi.org/10.1007/s11465-022-0738-7

本期目录

Design and evaluation of a novel biopsy needle with hemostatic function

Xiaolong ZHU¹, Yichi MA², Xiao XIAO¹, Liang LU¹, Wei XIAO¹, Ziqi ZHAO¹, Hongliang REN³(

), Max Q.-H. MENG¹(

)

¹. Department of Electronic and Electrical Engineering, Southern University of Science and Technology, Shenzhen 518055, China
². Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA 48072, USA
³. Department of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong, China

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Abstract：

Biopsy is a method commonly used for early cancer diagnosis. However, bleeding complications of widely available biopsy are risky for patients. Safer biopsy will result in a more accurate cancer diagnosis and a decrease in the risk of complications. In this article, we propose a novel biopsy needle that can reduce bleeding during biopsy procedures and achieve stable hemostasis. The proposed biopsy needle features a compact structure and can be operated easily by left and right hands. A predictive model for puncture force and tip deflection based on coupled Eulerian–Lagrangian (CEL) method is developed. Experimental results show that the biopsy needle can smoothly deliver the gelatin sponge hemostatic plug into the tissue. Although the hemostatic plug bends, the overall delivery process is stable, and the hemostatic plug retains in the tissue without being affected by the withdrawal of the needle. Further experiments indicate that the specimens are well obtained and evenly distributed in the groove of the outer needle without scattering. Our proposed design of biopsy needle possesses strong ability of hemostasis, tissue cutting, and tissue retention. The CEL model accurately predicts the peak of puncture force and produces close estimation of the insertion force at the postpuncture stage and tip position.

Key words： cancer diagnosis biopsy needle hemostatic function predictive model coupled Eulerian−Lagrangian

收稿日期: 2022-02-16 出版日期: 2023-05-04

Corresponding Author(s): Hongliang REN,Max Q.-H. MENG

引用本文:

. [J]. Frontiers of Mechanical Engineering, 2023, 18(2): 22.
Xiaolong ZHU, Yichi MA, Xiao XIAO, Liang LU, Wei XIAO, Ziqi ZHAO, Hongliang REN, Max Q.-H. MENG. Design and evaluation of a novel biopsy needle with hemostatic function. Front. Mech. Eng., 2023, 18(2): 22.

链接本文:

https://academic.hep.com.cn/fme/CN/10.1007/s11465-022-0738-7
https://academic.hep.com.cn/fme/CN/Y2023/V18/I2/22

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Fig.5

Tab.1

Fig.6

Fig.7

Property	Value
Young’s modulus of the needle, $E n$	$2 × 105$ MPa
Poisson’s ratio of the needle, $ν n$	0.3
Density of the needle, $ρ n$	7850 kg/m³
Density of the tissue, $ρ t$	1130 kg/m³
Shear modulus of the tissue, $C 10$	$3.2 × 10 ? 3$ MPa
Relaxation modulus of part 1, $g 1$	0.78 MPa
Relaxation time of part 1, $τ 1$	0.42 s
Relaxation modulus of part 2, $g 2$	0.07 MPa
Relaxation time of part 2, $τ 2$	9.84 s

Tab.2

Fig.8

Fig.9

Fig.10

Fig.11

Fig.12

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