In vitro degradation of MAO/PLA coating on Mg--1.21Li--1.12Ca--1.0Y alloy

doi:10.1007/s11706-014-0264-6

Frontiers of Materials Science

2014, Vol. 8

Issue (4): 343-353 https://doi.org/10.1007/s11706-014-0264-6

本期目录

In vitro degradation of MAO/PLA coating on Mg--1.21Li--1.12Ca--1.0Y alloy

Rong-Chang ZENG^1,^2,^*(

),Wei-Chen QI^1,²,Ying-Wei SONG³,Qin-Kun HE¹,Hong-Zhi CUI¹,En-Hou HAN³

1. College of Materials Science and Engineering, Shandong University of Science and Technology, Qingdao 266590, China
2. State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology, Shandong University of Science and Technology, Qingdao 266590, China
3. National Engineering Center for Corrosion Control, Institute of Metals Research, Chinese Academy of Sciences, Shenyang 110016, China

全文: PDF(2330 KB) HTML

Abstract：

Magnesium and its alloys are promising biomaterials due to their biocompatibility and osteoinduction. The plasticity and corrosion resistance of commercial magnesium alloys cannot meet the requirements for degradable biomaterials completely at present. Particularly, the alkalinity in the microenvironment surrounding the implants, resulting from the degradation, arouses a major concern. Micro-arc oxidation (MAO) and poly(lactic acid) (PLA) composite (MAO/PLA) coating on biomedical Mg--1.21Li--1.12Ca--1.0Y alloy was prepared to manipulate the pH variation in an appropriate range. Surface morphologies were discerned using SEM and EMPA. And corrosion resistance was evaluated via electrochemical polarization and impedance and hydrogen volumetric method. The results demonstrated that the MAO coating predominantly consisted of MgO, Mg₂SiO₄ and Y₂O₃. The composite coating markedly improved the corrosion resistance of the alloy. The rise in solution pH for the MAO/PLA coating was tailored to a favorable range of 7.5--7.8. The neutralization caused by the alkalinity of MAO and Mg substrate and acidification of PLA was probed. The result designates that MAO/PLA composite coating on Mg--1.21Li--1.12Ca--1.0Y alloys may be a promising biomedical coating.

Key words： magnesium alloy micro-arc oxidation (MAO) poly(lactic acid) (PLA) biomaterial degradation

收稿日期: 2014-07-20 出版日期: 2014-12-04

Corresponding Author(s): Rong-Chang ZENG

引用本文:

. [J]. Frontiers of Materials Science, 2014, 8(4): 343-353.
Rong-Chang ZENG,Wei-Chen QI,Ying-Wei SONG,Qin-Kun HE,Hong-Zhi CUI,En-Hou HAN. In vitro degradation of MAO/PLA coating on Mg--1.21Li--1.12Ca--1.0Y alloy. Front. Mater. Sci., 2014, 8(4): 343-353.

链接本文:

https://academic.hep.com.cn/foms/CN/10.1007/s11706-014-0264-6
https://academic.hep.com.cn/foms/CN/Y2014/V8/I4/343

Fig.1

Tab.1

Fig.2

Fig.3

Fig.4

Fig.5

Fig.6

Tab.2

Fig.7

Fig.8

Fig.9

Fig.10

Fig.11

1	Staiger M P, Pietak A M, Huadmai J, . Magnesium and its alloys as orthopedic biomaterials: a review. Biomaterials, 2006, 27(9): 1728-1734
2	Zhao L, Cui C, Wang Q, . Growth characteristics and corrosion resistance of micro-arc oxidation coating on pure magnesium for biomedical applications. Corrosion Science, 2010, 52(7): 2228-2234
3	Witte F, Fischer J, Nellesen J, . In vitro and in vivo corrosion measurements of magnesium alloys. Biomaterials, 2006, 27(7): 1013-1018
4	Li Z, Gu X, Lou S, . The development of binary Mg–Ca alloys for use as biodegradable materials within bone. Biomaterials, 2008, 29(10): 1329-1344
5	Song G, Song S. A possible biodegradable magnesium implant material. Advanced Engineering Materials, 2007, 9(4): 298-302
6	Witte F. The history of biodegradable magnesium implants: a review. Acta Biomaterialia, 2010, 6(5): 1680-1692
7	Gray J, Luan B. Protective coatings on magnesium and its alloys — a critical review. Journal of Alloys and Compounds, 2002, 336(1-2): 88-113
8	Xin Y, Hu T, Chu P K. In vitro studies of biomedical magnesium alloys in a simulated physiological environment: a review. Acta Biomaterialia, 2011, 7(4): 1452-1459
9	Witte F, Kaese V, Haferkamp H, . In vivo corrosion of four magnesium alloys and the associated bone response. Biomaterials, 2005, 26(17): 3557-3563
10	Liu C L, Wang Y J, Zeng R C, . In vitro corrosion degradation behaviour of Mg–Ca alloy in the presence of albumin. Corrosion Science, 2010, 52(10): 3341-3347
11	Kim W C, Kim J G, Lee J Y, . Influence of Ca on the corrosion properties of magnesium for biomaterials. Materials Letters, 2008, 62(25): 4146-4148
12	Zhang S, Li J, Song Y, . In vitro degradation, hemolysis and MC3T3-E1 cell adhesion of biodegradable Mg–Zn alloy. Materials Science and Engineering C, 2009, 29(6): 1907-1912
13	Zhang C-Y, Zeng R-C, Liu C-L, . Comparison of calcium phosphate coatings on Mg–Al and Mg–Ca alloys and their corrosion behavior in Hank’s solution. Surface and Coatings Technology, 2010, 204(21-22): 3636-3640
14	Zhang C Y, Zeng R C, Chen R S, . Preparation of calcium phosphate coatings on Mg–1.0Ca alloy. Transactions of Nonferrous Metals Society of China, 2010, 20: s655-s659
15	Zeng R C, Dietzel W, Witte F, . Progress and challenge for magnesium alloys as biomaterials. Advanced Engineering Materials, 2008, 10(8): B3-B14
16	Zeng R C, Guo X L, Liu C L, . Study on corrosion of medical Mg–Ca and Mg–Li–Ca alloys. Acta Metallurgica Sinica, 2012, 47: 1477-1482
17	Zeng R C, Sun L, Zheng Y F, . Corrosion and characterisation of dual phase Mg–Li–Ca alloy in Hank’s solution: The influence of microstructural features. Corrosion Science, 2014, 79: 69-82
18	Witte F, Fischer J, Nellesen J, . In vivo corrosion and corrosion protection of magnesium alloy LAE442. Acta Biomaterialia, 2010, 6(5): 1792-1799
19	Zhao X, Shi L L, Xu J. A comparison of corrosion behavior in saline environment: rare earth metals (Y, Nd, Gd, Dy) for alloying of biodegradable magnesium alloys. Journal of Materials Science and Technology, 2013, 29(9): 781-787
20	Chen J, Zeng R C, Huang W J, . Characterization and wear resistance of macro-arc oxidation coating on magnesium alloy AZ91 in simulated body fluids. Transactions of Nonferrous Metals Society of China, 2008, 18: s361-s364
21	Sankara Narayanan T S N, Park I S, Lee M H. Strategies to improve the corrosion resistance of microarc oxidation (MAO) coated magnesium alloys for degradable implants: Prospects and challenges. Progress in Materials Science, 2014, 60: 1-71
22	Xu L, Pan F, Yu G, . In vitro and in vivo evaluation of the surface bioactivity of a calcium phosphate coated magnesium alloy. Biomaterials, 2009, 30(8): 1512-1523
23	Xu L, Yamamoto A. In vitro degradation of biodegradable polymer-coated magnesium under cell culture condition. Applied Surface Science, 2012, 258(17): 6353-6358
24	Hornberger H, Virtanen S, Boccaccini A R. Biomedical coatings on magnesium alloys - a review. Acta Biomaterialia, 2012, 8(7): 2442-2455
25	Gu X N, Li N, Zhou W R, . Corrosion resistance and surface biocompatibility of a microarc oxidation coating on an Mg-Ca alloy. Acta Biomaterialia, 2011, 7(4): 1880-1889
26	Xu L, Yamamoto A. Characteristics and cytocompatibility of biodegradable polymer film on magnesium by spin coating. Colloids and Surfaces B: Biointerfaces, 2012, 93: 67-74
27	Wu Y H, Li N, Cheng Y, . In vitro study on biodegradable AZ31 magnesium alloy fibers reinforced PLGA composite. Journal of Materials Science and Technology, 2013, 29(6): 545-550
28	Wong H M, Yeung K W, Lam K O, . A biodegradable polymer-based coating to control the performance of magnesium alloy orthopaedic implants. Biomaterials, 2010, 31(8): 2084-2096
29	Ostrowski N J, Lee B, Roy A, . Biodegradable poly(lactide-co-glycolide) coatings on magnesium alloys for orthopedic applications. Journal of Materials Science: Materials in Medicine, 2013, 24(1): 85-96
30	Guo M, Cao L, Lu P, . Anticorrosion and cytocompatibility behavior of MAO/PLLA modified magnesium alloy WE42. Journal of Materials Science: Materials in Medicine, 2011, 22(7): 1735-1740
31	Lu P, Cao L, Liu Y, . Evaluation of magnesium ions release, biocorrosion, and hemocompatibility of MAO/PLLA-modified magnesium alloy WE42. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2011, 96B(1): 101-109
32	Zhang R F, Zhang S F, Duo S W. Influence of phytic acid concentration on coating properties obtained by MAO treatment on magnesium alloys. Applied Surface Science, 2009, 255(18): 7893-7897
33	Gaurava S, Ankita M, Pradeep S. Characterization and in vitro degradation studies of synthesized polylactide (PLA). Research Journal of Chemistry and Environment, 2012, 16: 2
34	Bonilla F, Berkani A, Skeldon P, . Enrichment of alloying elements in anodized magnesium alloys. Corrosion Science, 2002, 44(9): 1941-1948
35	Sreekanth D, Rameshbabu N, Venkateswarlu K, . Effect of K2TiF6 and Na2B4O7 as electrolyte additives on pore morphology and corrosion properties of plasma electrolytic oxidation coatings on ZM21 magnesium alloy. Surface and Coatings Technology, 2013, 222: 31-37
36	Piemonte V, Gironi F. Kinetics of hydrolytic degradation of PLA. Journal of Polymers and the Environment, 2013, 21(2): 313-318
37	Ghasemi A, Raja V S, Blawert C, . The role of anions in the formation and corrosion resistance of the plasma electrolytic oxidation coatings. Surface and Coatings Technology, 2010, 204(9-10): 1469-1478
38	Wang L, Pan C. Characterisation of microdischarge evolution and coating morphology transition in plasma electrolytic oxidation of magnesium alloy. Surface Engineering, 2007, 23(5): 324-328

Viewed

Full text

Abstract

Cited

Shared

Discussed